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A prospective experimental comparative study on the clinical and antimicrobial effects of chlorine dioxide based toothpaste and mouthrinse in periodontitis patients- A One Year Follow-up Study

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Abstract

Aim: The present study was aimed to assess and compare the clinical and antimicrobial effects of sodium chlorite based toothpaste and mouthrinse in periodontitis patients. Materials and methods: A total 50 generalized chronic periodontitis patient between the ages of 18 and 55 years were enrolled in the study and divided under two categories (A and B). Clinical and microbiological parameters were recorded prior to phase 1 therapy; and subjects were put on conventional oral hygiene regime and sodium chlorite based toothpaste and mouthrinse. Results: The results of this study showed that there was significant decrease in clinical, and microbiological parameters from baseline to 12 months in both the groups (p < 0.01). The subjects under test group (sodium chlorite based toothpaste and mouthrinse) showed a highly significant reduction to all the parameters as compared to subjects under group B. Conclusion: sodium chlorite based toothpaste and mouthrinse will be a true alternative for maintaining oral hygiene.

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... This mouthwash is a topical bactericide, its action is to reduce bacteria in the oral cavity by inhibiting ammonia production and preventing the ulcers from secondary contamination, this is the goal of healing the lesions. 10,[18][19][20] Complete healing of these lesions will only occur if the serum urea values return to normal. It was difficult to achieve in this patient although he had already undergone haemodialysis but the kidney function was difficult to improve, this was because he was suffering from AKI on CKD which lead the kidney function became difficult to work normally. ...
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