This paper investigates how lesbian, gay, bisexual, and transgender (LGBT) rights movements in Ghana, both anti and pro, framed the debate that captured media attention in 2006 and 2011. Decolonisation and human rights frames were appropriated, challenged, and dominated by opponents of LGBT rights, making it difficult for LGBT activists to use them. The opponents' corruption frame overpowered the ... [Show full abstract] LGBT activists' preservation frame. When LGBT activists used a human rights frame (comparing sexual minorities to racial minorities and to persons with disabilities), the countermovement appropriated it in a way that excluded same-sex relations by comparing sexual minorities to "deviants", persons with mental illnesses, and animals. The interaction between the decolonisation and human rights frames was also problematic: the corruption frame not only rendered the LGBT activists' preservation frame nearly useless, but it also made their use of the human rights frame appear to be cultural imperialism and problematised the help they received from international LGBT organisations.