... Thousands of research articles that have been published in international medical journals are available on the internet regarding studies on the medicinal properties the seeds of black cumin (BC, Nigella sativa L.), their oil and their bioactive compounds (Randhawa, 2008). Over the last two decades, several reviews have provided comprehensive information on the nutritional, health, pharmaceutical, therapeutic and biomedical applications and prospects of BC (Randhawa and Al-Ghamdi, 2002;Ali and Blunden, 2003;Gilani et al., 2004;Salem, 2005;El-Tahir et al., 2006;Akhondian et al., 2007;Ramadan, 2007;Ismail and Yaheya, 2009;Sharma et al., 2009;Paarakh, 2010;Randhawa and Alghamdi, 2011;Naz, 2011;Shrivastava et al., 2011;Mirzaei, 2012;Datta et al., 2012;Ahmad et al., 2013;Alenzi et al., 2013;Azeem et al., 2014;Forouzanfar et al., 2014;Mollazadeh and Hosseinzadeh, 2014;Razavi and Hosseinzadeh, 2014;Tembhurne et al., 2014;Aljabre et al., 2015;Bamosa, 2015;Gali-Muhtasib et al., 2006;Gholamnezhad et al., 2015;Heshmati and Namazi, 2015;Longato et al., 2015;Mahdavi et al., 2015;Majdalawieh and Fayyad, 2015;Amin and Hosseinzadeh, 2016;Beheshti et al., 2016;Gholamnezhad et al., 2016;Hayatdavoudi et al., 2016;Hussain and Hussain, 2016;Khan et al., 2016;Kooti et al., 2016;Mohtashami and Entezari, 2016;Sahebkar et al., 2016aSahebkar et al., , 2016bShokri, 2016;Ijaz et al., 2017;Tavakkoli et al., 2017;Mazaheri et al., 2019). ...