Quality of life is defined as “an individual perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns.” Quality of life is a measure of a person’s physical and psychological contentment. The study was conducted in order to study the impact of clinical pharmacist’s counseling on Qol ... [Show full abstract] in patients with heart failure using Kansas City Cardiomyopathy Questionnaire (K.C.C.Q). The study was conducted on 70 patients and the influence of various intra and inter patient elements like age, gender, ejection fraction, duration of the disease on the questionnaire were studied. Compliance was assessed by pill count method. Subsequently the patients were counseled and followed for a period of time. A significant difference in QoL score and compliance was achieved compared to that of the baseline. By the end of the study more patients were found to be compliant. In conclusion, Patient counseling aided the patients in better understanding of the disease and its control which ultimately improved their health related Quality of life.