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Young people with features of gender dysphoria: Demographics and associated difficulties

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This article presents the findings from a cross-sectional study on demographic variables and associated difficulties in 218 children and adolescents (Mean age = 14 years, SD = 3.08, range = 5-17 years), with features of gender dysphoria, referred to the Gender Identity Development Service (GIDS) in London during a 1-year period (1 January 2012-31 December 2012). Data were extracted from patient files (i.e. referral letters, clinical notes and clinician reports). The most commonly reported associated difficulties were bullying, low mood/depression and self-harming. There was a gender difference on some of the associated difficulties with reports of self-harm being significantly more common in the natal females and autism spectrum conditions being significantly more common in the natal males. The findings also showed that many of the difficulties increased with age. Findings regarding demographic variables, gender dysphoria, sexual orientation and family features are reported, and limitations and implications of the cross-sectional study are discussed. In conclusion, young people with gender dysphoria often present with a wide range of associated difficulties which clinicians need to take into account, and our article highlights the often complex presentations of these young people. © The Author(s) 2014.
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Psychiatry
Clinical Child Psychology and
http://ccp.sagepub.com/content/early/2014/11/26/1359104514558431
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DOI: 10.1177/1359104514558431
published online 26 November 2014Clin Child Psychol Psychiatry
Vicky Holt, Elin Skagerberg and Michael Dunsford
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Young people with features of gender dysphoria: Demographics and associated
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DOI: 10.1177/1359104514558431
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Young people with features of
gender dysphoria: Demographics
and associated difficulties
Vicky Holt, Elin Skagerberg and Michael
Dunsford
The Tavistock and Portman NHS Foundation Trust, UK
Abstract
This article presents the findings from a cross-sectional study on demographic variables and
associated difficulties in 218 children and adolescents (Mean age = 14 years, SD = 3.08, range = 5–
17 years), with features of gender dysphoria, referred to the Gender Identity Development
Service (GIDS) in London during a 1-year period (1 January 2012–31 December 2012). Data
were extracted from patient files (i.e. referral letters, clinical notes and clinician reports). The
most commonly reported associated difficulties were bullying, low mood/depression and self-
harming. There was a gender difference on some of the associated difficulties with reports of
self-harm being significantly more common in the natal females and autism spectrum conditions
being significantly more common in the natal males. The findings also showed that many of the
difficulties increased with age. Findings regarding demographic variables, gender dysphoria, sexual
orientation and family features are reported, and limitations and implications of the cross-sectional
study are discussed. In conclusion, young people with gender dysphoria often present with a wide
range of associated difficulties which clinicians need to take into account, and our article highlights
the often complex presentations of these young people.
Keywords
Gender dysphoria, associated difficulties, demographics, bullying, self-harm
Introduction
Gender dysphoria
Children and adolescents with gender dysphoria (GD) experience ‘a marked incongruence between
their experienced/expressed gender and assigned gender’ (American Psychiatric Association,
2013). GD, in itself, often results in profound distress to the individual, namely an intense, often
unbearable feeling of being ‘in the wrong body’. This often causes the young people to struggle in
a number of different areas in their lives. The distress and feeling of being in the wrong body often
Corresponding author:
Vicky Holt, The Tavistock and Portman NHS Foundation Trust, 120 Belsize Lane, London NW3 5BA, UK.
Email: vholt@tavi-port.nhs.uk
558431CCP0010.1177/1359104514558431Clinical Child Psychology and PsychiatryHolt et al.
research-article2014
Article
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2 Clinical Child Psychology and Psychiatry
increases at the onset of puberty due to an intensification of feelings of incongruence between self-
perception and the body (e.g. Steensma, Biemond, De Boer, & Cohen-Kettenis, 2011). The con-
stant conflicting relationship with their natal gender and the often unbearable pubertal changes
often result in young people with GD withdrawing socially and feeling depressed and low in self-
esteem. At times this results in self-harm and/or suicidal feelings (e.g. Skagerberg, Parkinson, &
Carmichael, 2013).
Associated difficulties
An audit by Di Ceglie, Freedman, McPherson, and Richardson (2002), looking at 124 young gen-
der dysphoric people in the United Kingdom, showed that more than half of the young people
experienced relationship difficulties with peers and/or parents/carers and that 42% experienced
depression. Several other papers confirm that children and adolescents with GD often present with
a number of associated difficulties. De Vries, Doreleijers, Steensma, and Cohen-Kettenis (2011)
looked at psychiatric comorbidity in 105 gender dysphoric adolescents in Holland and found that
10% of the young people suffered with social phobia, 21% with anxiety disorders, 12.4% with
mood disorders and 11.4% with disruptive disorders. Skagerberg, Davidson, and Carmichael
(2013) examined externalising (e.g. ‘acting out’) and internalising (e.g. withdrawn, depressed)
behaviours in a sample of 141 gender dysphoric adolescents who had attended an assessment of
4–6 sessions at the Gender Identity Development Service (GIDS). They found that overall the
adolescents showed significantly higher levels of internalising than externalising behaviours.
Moreover, the natal males presented with significantly more internalising behaviours than the natal
females, thus, scoring more in line with their perceived rather than natal gender.
Several other studies have looked at internalising and externalising behaviours in children and
adolescents with GD. Zucker and Bradley (1995) examined parent reports (Child Behaviour
Checklist (CBCL)) of 161 boys with GD between the age of 4 and 11 years and 90 male siblings.
They found that the boys with GD had significantly more behavioural problems compared to their
male siblings and that they also had significantly more internalising than externalising behaviours.
Also, Steensma et al. (2014) looked at behavioural and emotional difficulties and peer relations
using the Teacher’s Report Form in a sample of 728 young people referred to gender identity clin-
ics in the Netherlands and Canada. They found that internalising behaviours were more common
than externalising behaviours and that the children were better functioning than the adolescents,
thus highlighting the increased distress around the onset of puberty. In line with the findings by
Skagerberg, Davidson, and Carmichael (2013), the natal males showed more internalising behav-
iours than the natal females. Furthermore, more emotional and behavioural difficulties were found
in Canada than in the Netherlands, and this was found to be partly attributable to poorer peer
relations.
The incongruence between self-perception and the body is not likely to be the sole contributing
factor to the distress often experienced in this group of young people. Young people with GD fre-
quently suffer with discrimination and prejudice which can itself result in fear, distress and other
associated difficulties (Grant et al., 2011). Zucker et al. (2012), for example, found that the major-
ity of the gender dysphoric youth in their study had difficulties with peer relations, and Cohen-
Kettenis, Owen, Kaijser, Bradley, and Zucker (2003) examined demographic characteristics, social
competence and behavioural difficulties in 488 children referred to gender identity clinics in
Toronto and Utrecht and found that poor peer relations were the strongest predictor of behavioural
difficulties.
Whereas some of the aforementioned associated difficulties are likely to be linked to the GD
itself, other associated difficulties are likely to be related to the effects of the discrimination and
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Holt et al. 3
prejudice often experienced in young people with GD. Therefore, gaining a better understanding
of what the associated difficulties are, and being able to work with young people and their families
by trying to help ameliorate some of these difficulties alongside the GD, will be of benefit. A good
understanding of the associated difficulties is also important in the assessment, formulation and
clinical management, taking into account the complexities and specific needs of these young
people.
The present study
This cross-sectional study intended to provide an overview of demographic characteristics and
associated difficulties in young gender dysphoric people. It follows on from a 2002 audit by Di
Ceglie et al. conducted at the same gender identity service in London and includes a larger sample
and a different focus. We wanted to get a snapshot of the lives of gender dysphoric young people
and the challenges they face, and so we examined a number of different variables from the age of
first gender dysphoric feelings and sexual orientation to associated difficulties such as self-harm,
suicidality, low mood/depression, psychosis and eating difficulties. We also recorded family
makeup, looking specifically at divorce rates, siblings, living arrangements and other familial dif-
ficulties. We thought it might be helpful to have a greater understanding of the sexual orientation
of the young people referred as well as school attendance and bullying. By being more aware of the
range of difficulties young people with GD experience, clinicians can provide them with better and
more appropriate support and care.
Method
Participants
The participants were 218 children and adolescents (Mean age at referral = 14 years, standard devi-
ation (SD) = 3.08, range = 5–17 years) with features of GD attending the GIDS in London. A total
of 37.2% of the young people referred were natal males (Mean age at referral = 13.15 years,
SD = 3.76) and 62.8% were natal females (Mean age at referral = 14.51 years, SD = 2.47).
Information regarding ethnicity was not available for 18.8% (N = 41) of the young people. The
ethnicity of the remaining 177 young people was 88.7% White British, 2.2% Black Caribbean,
2.2% any other mixed background, 2.2% any other White background, 1.1% mixed Black
Caribbean and White, 0.6% mixed Black, 0.6% Asian-Pakistani, 0.6% Asian-Indian, 0.6% Asian-
Chinese, 0.6% mixed White and Asian and 0.6% White Irish.
The GIDS is a national highly specialist gender service covering the United Kingdom, as part
of the National Health Service (NHS). Many of the young people attending the service frequently
present with a number of associated difficulties. The GIDS is a multidisciplinary service consisting
of child and adolescent psychotherapists, child and adolescent psychiatrists, clinical psychologists,
social workers, researchers and trainees.
Data collected
Data were collected for all new referrals to the GIDS in London during a 1-year period (1 January
2012–31 December 2012). The age inclusion criterion was 0–18 years. During this period, 303
children and adolescents were referred to the GIDS. A total of 85 cases were excluded from the
study due to being children who received counselling in relation to having a transsexual parent (as
the children themselves were not gender dysphoric), cases that were referred to the GIDS Leeds
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4 Clinical Child Psychology and Psychiatry
base (i.e. our second centre in Leeds) which the researchers therefore did not have easy access to
or cases that did not result in a first appointment. So data were collected from a total of 218 cases.
The data collected comprised 25 variables: the natal gender, the age of the young person at the
time of the referral, ethnicity, whether they were in education, whether they were living in their
chosen gender, whether they preferred to be referred to by a name different from the name given to
them at birth, sexual orientation, age of first gender dysphoric feelings, family variables (e.g. who
the young people lived with, number of biological siblings, parental depression and alcohol use,
domestic violence, migration) and associated difficulties. The associated difficulties included non-
suicidal self-harm, suicidal ideation, suicide attempts, autism spectrum conditions (ASCs), atten-
tion deficit hyperactivity disorder (ADHD), symptoms of anxiety, psychosis, eating difficulties,
bullying and abuse (i.e. physical, psychological/emotional, sexual abuse and neglect). We were
interested in the challenges that young people face before coming to the service, and so the data
were ascertained from referral letters but also from clinical notes and clinician reports mentioning
any information about the young people before they attended the GIDS. All data were anonymised
in order to ensure the confidentiality of the individuals.
Procedure
The research was carried out by the GIDS consultant child and adolescent psychiatrist, GIDS
research psychologist and GIDS assistant psychologist. Once a list of patients who were referred
to the GIDS between January 2012 and January 2013 had been made and the 85 cases had been
removed (see the above section on data collected), the referral letters and GIDS clinician notes/
reports from each of the 218 remaining case files were systematically read by one of the three
GIDS members. Any reference to associated difficulties prior to attendance at the service, or other
information collected, was recorded on an excel spreadsheet. Data were only recorded when it was
clearly stated in the file. After completion, the data were transferred to SPSS and analysed by the
research psychologist. The research was then written up jointly by the consultant child and adoles-
cent psychiatrist, the research psychologist and the assistant psychologist.
Results
GD and sexual orientation
Information regarding the age of the first gender dysphoric feelings was not available for 4.6% of
the cases (N = 10). For the remaining 208 people, 42.7% reported having their first gender dys-
phoric feelings between 0 and 6 years of age, 34.9% between 7 and 12 years of age and 17.9%
between 13 and 18 years of age. Statistically, no significant difference was found regarding the age
of first gender dysphoric feelings between the genders (χ2(2) = 4.97, p > .05, see Table 1 for more
information).
Overall, 47.8% of the young people preferred to be referred to by a different name from their
birth name, and this percentage differed significantly between the genders (χ2(1) = 41.76, p < .001)
with 67.2% of the natal females and 20.8% of the natal males preferring to be referred to by a name
different to that given to them at birth. Data regarding whether the young people were living in
their chosen gender was not available for 6.4% of the cases (N = 14). For the remaining 205 people,
54.6% were living in their chosen gender full-time, 9.8% part-time and 35.6% were not living in
their chosen gender. A chi-square test revealed that there was a significant difference in the fre-
quency of natal males and natal females living in their chosen gender (full-time or part-time) with
the natal females more often living in their chosen gender than the natal males (χ2(1) = 18.73,
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Holt et al. 5
p < .001). If we separate the percentages by those who live in their chosen gender full-time and
part-time, we find that 69.2% of the natal females were living in their chosen gender full-time
and 6.2% part-time whereas 29.3% of the natal males were living in their chosen gender full-time
and 16% part-time. It is, however, important to remember that the natal males in this study were,
on average, slightly younger (Mean age at referral = 13.15 years, SD = 3.76) than the natal females
(Mean age at referral = 14.51 years, SD = 2.47) and this may have influenced the results.
Information regarding sexual orientation was available for 56.7% (N = 97) of the young people
12 years of age and above (see Table 2 for more details).
Family: features and composition
The mean number of biological siblings was 1.39 (SD = 1.31, range = 0–8). A total of 58.3% of the
young people had parents who had separated, and domestic violence was indicated in 9.2% of the
cases. Maternal depression was indicated in 19.3% of the cases (4.1% post natal) and paternal
depression in 5% of the cases. Parental alcohol/drug abuse was indicated in 7.3% of the cases.
Table 3 shows the living arrangements at the time of referral for all 218 participants.
Associated difficulties
Overall, the three most common associated difficulties were bullying (47%), low mood/depression
(42%) and self-harming (39%). Table 4 shows the percentage of associated difficulties for the natal
males and females separately. For the natal females, self-harm and bullying were the two most
common difficulties whereas for the natal males it was bullying and low mood/depression. Chi-
square tests showed that reports of actual self-harm (χ2(1) = 8.65, p < .01) were significantly more
common in the natal females than the natal males. This finding supports those by Skagerberg,
Parkinson, and Carmichael (2013) looking at self-harming thoughts and behaviours in young peo-
ple with GD. ASC diagnoses and queries were found to be significantly more common in the natal
males (χ2(1) = 7.33, p < .01). No significant difference was found between the genders in terms of
Table 1. The percentage of natal females (N = 129) and males (N = 79) having their first gender dysphoric
feelings between ages 0–6, 7–12 and 13–18 years.
Age of first gender
dysphoric feelings
Natal males Natal females
0–6 years 54.4% (N = 43) 38.3% (N = 50)
7–12 years 29.1% (N = 23) 41.1% (N = 53)
13–18 years 16.5% (N = 13) 20.2% (N = 26)
Table 2. The sexual orientation of the natal males and females over the age of 12 years for whom data
were available (N = 97, 71 natal females and 26 natal males).
Sexual orientation Natal males Natal females
Attracted to females 19.2% (N = 5) 67.6% (N = 48)
Attracted to males 42.3% (N = 11) 8.5% (N = 6)
Bisexual 38.5% (N = 10) 21.1% (N = 15)
Asexual 0% (N = 0) 2.8% (N = 2)
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6 Clinical Child Psychology and Psychiatry
Table 3. The living arrangements at the time of referral for all participants (N = 218).
Living with Percentage N
Both biological parents 36.7% 80
Mother 31.2% 68
Mother and step father 11.9% 26
Foster care 4.1% 9
Father 3.2% 7
Father and step mother 3.2% 7
Alternated between separated parents 1.8% 4
Independently 1.8% 3
Grandparents 1.4% 3
Adoptive parents 0.9% 2
Partner’s family 0.9% 2
Boarding school 0.5% 1
Aunt 0.5% 1
Supported accommodation 0.5% 1
Children’s home 0.5% 1
Mother and grandparents 0.5% 1
Unknown 0.9% 2
reports on suicidal ideation, suicide attempts, low mood/depression, abuse, ADHD, anxiety, psy-
chosis, eating difficulties and bullying.
Table 5 shows that, overall, many of the associated difficulties increased with age. Chi-squared
tests showed that there was a significant relationship between age and self-harm (χ2(1) = 12.18,
p < .001), suicidal ideation (χ2(1) = 9.1, p < .01), suicidal attempts (χ2(1) = 5.17, p < .05), low mood/
depression (χ2(1) = 24.61, p < .001) and eating difficulties (χ2(1) = 7.75, p < .01). There was no sig-
nificant relationship between age and bullying, ASC, ADHD, symptoms of anxiety, psychosis and
abuse (all ps > .05). If we look at, for example, self-harm we can see that there were reports of self-
harm in 14.6% of the 5- to 11-year-olds and 44.1% of the 12- to 18-year-olds. Similarly, 7.3% of
Table 4. The percentage of associated difficulties in natal males and females (N = 218, 137 natal females
and 81 natal males).
Associated difficulties Natal males Natal females
Self-harm 25.9% (n = 21) (+ thoughts in 4.9%) 46% (N = 63) (+ thoughts in 3.6%)
Suicidal ideation 38.3% (N = 31) 32.8% (N = 45)
Suicidal attempts 12.3% (N = 10) 13.9% (N = 19)
Low mood/depression 45.7% (N = 37) 39.4% (N = 54)
ASC 18.5% (N = 15) (+ query in 7.4%) 10.2% (N = 14) (+ query in 1.5%)
ADHD 12.3% (N = 10) 5.8% (N = 8)
Symptoms of anxiety 21.0% (N = 17) 23.4% (N = 32)
Psychosis 3.7% (N = 3) 5.8% (N = 8)
Eating difficulties 12.3% (N = 10) 13.9% (N = 19)
Bullying 49.4% (N = 40) 45.3% (N = 62)
Abuse 11.1% (N = 9) 21.2% (N = 29)
ASC: autism spectrum conditions; ADHD: attention deficit hyperactivity disorder.
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Holt et al. 7
the 5- to 11-year-olds reported feeling low in mood whereas 49.7% of the 12- to 18-year-olds
reported feeling low in mood. These findings highlight that puberty is often a time of increased
distress for young people with GD.
Discussion
Most common associated difficulties and comparisons with previous studies
The findings from this cross-sectional study showed that, overall, the three most common associ-
ated difficulties were: bullying (47%), low mood/depression (42%) and self-harming (39%). If we
compare these findings to those of Di Ceglie et al. (2002), we find that the percentage of young
people who were depressed/low in mood was the same (42%) whereas the percentage of young
people who were harassed/bullied was lower in their study (33%) as was the number of young
people who were involved in self-injurious behaviours (18%). The percentage of people who were
involved in self-harming in the current study was higher than in a study by Skagerberg, Parkinson,
and Carmichael (2013) where, overall, 24% of the children and adolescents with GD were reported
to self-harm. It is possible that the higher percentage of young people self-harming in the current
study compared to those in earlier studies simply reflect trends in the general population (see
Muehlenkamp, Claes, Havertape, & Plener, 2012).
Comparisons between natal females and natal males
Our findings showed that there was a significant difference in the occurrence of self-harming and
ASC in the natal males and natal females with self-harming being indicated more often in the natal
females and ASC being indicated more often in the natal males. The higher occurrence of self-
harm in the natal females in this study concurs with, for example, Skagerberg, Parkinson, and
Carmichael (2013) who looked at self-harming thoughts and behaviours in 125 gender dysphoric
children and adolescents, and with Fox and Hawton (2004) and recent figures from the Health &
Social Care Information Centre (2013) in the United Kingdom looking at self-harming in adoles-
cents in the general population. The higher occurrence of ASC in the natal males accords with a
study by De Vries et al. (2011) looking at ASC in children and adolescents referred to the Gender
Identity Clinic in Amsterdam. However, whereas they found an incidence of ASC in 7.8% of their
Table 5. The percentage of young people with associated difficulties in the different age categories.
Associated difficulties 5–11 years (N = 41) 12–18 years (N = 177)
Self-harm 14.6% (+ thoughts in 4.9%) 44.1% (+ thoughts in 4%)
Suicidal ideation 14.6% 39.5%
Suicidal attempts 2.4% 15.8%
Low mood/depression 7.3% 49.7%
ASC 12.2% (+ query in 4.9%) 13.6% (+ query in 3.4%)
ADHD 14.6% 6.8%
Symptoms of anxiety 17.1% 23.7%
Psychosis 2.4% 5.7%
Eating difficulties 0% 16.4%
Bullying 36.6% 49.2%
Abuse 9.8% 19.2%
ASC: autism spectrum conditions; ADHD: attention deficit hyperactivity disorder.
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8 Clinical Child Psychology and Psychiatry
sample of 204 children and adolescents, in the current study we found that ASC was indicated in
13.3% of the young people. It is important to note, though, that the Dutch team used the Diagnostic
Interview for Social and Communication Disorders (DISCO) to assess ASC, while the young peo-
ple in our sample may not all have been formerly diagnosed.
Interestingly, natal females presented to our services more frequently than natal males; this shift
opposes historical trends where more natal males were referred. Also, significantly more natal
females than natal males were living in their chosen gender and/or were referred to by a name
different from that given to them at birth. It is important for clinicians to be aware of the gender
difference on some of the associated difficulties as well as the difference between natal males and
females in terms of living in their chosen gender and changing their name. Natal males and females
may, thus, need to be thought about separately and may require different interventions. As already
mentioned in the results, however, it is important to remember that the natal males in this study
were, on average, 1 year younger than the natal females and this may have influenced the results.
Distress around puberty
Our findings showed that puberty seemed to be a time of increased distress for many of the gender
dysphoric young people. A total of 14.6% of the 5- to 11-year-olds and 39.5% of the 12- to 18-year-
olds reported feeling suicidal. Similar patterns emerged for low mood/depression and self-harm.
This finding accords with the literature on gender dysphoric young people (e.g. Di Ceglie et al.,
2002; Skagerberg, Parkinson, & Carmichael, 2013) and on the general population (e.g. ‘Truth
Hurts’, 2006), which suggests an average age of onset of 12 years for distress associated with
pubertal changes.
Sexuality
Many of the natal females and natal males described being attracted to the opposite sex (to the
gender they identified as). This information is useful as it further informs our understanding of
young people’s sexual identity. Negotiating ones sexual orientation is an important developmental
task for all adolescents and may be more complex for young people with GD and professionals
must, thus, be sensitive to the sexual identity of their patients.
Clinical implications
The findings highlight the importance for clinicians to be mindful of the associated difficulties
linked to GD and to consider what factors are important in increasing these young people’s strength
and resilience (see Grossman, D’Augelli, & Frank, 2011). Clinically young people may present
with GD but also with a number of other psychological difficulties, and one difficulty may precipi-
tate another. High levels of bullying, harassment and abuse were reported and so all services must
ensure that any child protection concerns are responded to urgently. GD in a heteronormative soci-
ety undoubtedly predisposes a young person to a number of other difficulties ranging from social
isolation, stigma and shame to psychological issues such as depression, anxiety, self-harm and
eating disorders.
Our findings stress the need for services to work collaboratively in order to support a young
person with GD. General Practitioners, Child and Adolescent Mental Health Services (CAMHS),
education and specialist services each have important roles in ensuring that young people with GD
are provided with support in a number of areas of their lives. It is, for example, evident that there
are high levels of deliberate self-harm and suicidal ideation which require frequent and ongoing
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Holt et al. 9
support from CAMHS alongside the input from specialist gender services in order to alleviate the
distress. Clinicians therefore need to be particularly aware of signs of low mood and depression
and regularly screen for suicidal ideation and self-harming. This is especially important around
puberty which is often an extremely distressing time for young people with GD.
It is also important for the families to receive support, and a young person may require a number
of different interventions ranging from psychological support and/or medication for mental health
difficulties such as depression, school intervention to help reduce bullying and support regarding
which toilet or changing area to use. This may be alongside a young person being referred for the
hypothalamic blocker in order for the pubertal process to be halted in a reversible manner, allowing
the young person more time and space to explore their gender identity without the often devastat-
ing effects of puberty.
Links with ASC
Our findings show that a significant proportion of cases also have some social and communication
difficulties and are on the autistic spectrum. These young people may require support from more
specialist services, and an understanding of how this may relate to their gender identity is impor-
tant. For example, some young people with a comorbid diagnosis of GD and an ASC may hold
more rigid views of what it is to be male or female. Helping them to explore gender in a less stereo-
typical way may alleviate some of their distress and may deconstruct the gender binary. Conversely,
their perhaps more rigid views and more black and white style of thinking may make their gender
identity less fluid and more fixed (Di Ceglie, 2009; Di Ceglie, Skagerberg, Baron-Cohen, &
Auyeung, 2014).
Future research
More research is undoubtedly needed into links with associated difficulties. In some cases, for
example when a young person with GD is significantly depressed, it is important that the depres-
sion is understood and treated alongside the management of the GD. Undoubtedly, GD can lead to
low mood, but conversely depression can lead to doubts about ones identity in general, and clini-
cians need to take all of this information into account when working with children and adolescents
with GD and ensure that individualised multidisciplinary support is provided. Moreover, as this
cross-sectional study was done at the initial point of referral, it would be useful to follow it up once
the young people have received psychological and/or physical intervention (such as hormone
blockers and cross-sex hormones) to help us understand what factors might lead to amelioration of
the difficulties. Further research is also required to better understand which difficulties are a result
of the GD itself and which are a result of social shaming and stigmatisation of these young people
by society.
Limitations
This study has several limitations. First, the figures presented are likely to be an underestimate as
they were based on referral letters and clinician notes/reports. The referrers and clinicians may not
have asked about demographic variables and associated difficulties and/or may not have included
the information in their letters, notes or reports. Thus, if there was no mention of, for example, self-
harm, then it was assumed that the young person did not engage in this behaviour. It is perhaps
especially likely that more ‘internalising’ behaviours, such as low mood and anxiety, were under-
reported. Second, letters from referrers were sometimes very brief, and even though the GIDS has
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10 Clinical Child Psychology and Psychiatry
a standard referral form enquiring about many of the variables in this study, not all referrers had
completed this form. Finally, numbers were sometimes low, such as in the 5–11 age group, and
further research with a larger sample is needed in order for generalisations to be made from these
findings.
Conclusion
Young people with GD frequently present with associated difficulties. This cross-sectional study
has shown that some of the most common difficulties are bullying, self-harm and low mood/
depression. The findings presented are important as they will inform the management and under-
standing of young people with GD and they highlight the importance for clinicians to regularly
screen for associated difficulties in this group of young people and for them to keep in mind their
often complex presentations.
Funding
This research received no specific grant from any funding agency in the public, commercial or not-for-profit
sectors.
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Author biographies
Vicky Holt is a Consultant Child and Adolescent Psychiatrist working at the Gender identity Development
Service, a specialist national commissioning service. She has worked in this area for a number of years and is
a member of the WPATH child and adolescent committee.
Elin Skagerberg is a Research Psychologist in the Gender Identity Development Service at the Tavistock and
Portman NHS Foundation Trust. She has worked in this service since 2009 and has previsouly completed a
Ph.D. in Psychology at the University of Sussex. She has published a number of articles on gender dysphoria
as well as eyewitness testimony.
Michael Dunsford is an Assistant Psychologist/ Research Assistant in the Gender Identity Development
Service at the Tavistock and Portman NHS Foundation Trust. He joined this role shortly after graduating from
the University of Birmingham in 2012, where he studied Psychology, and is currently also taking a Master’s
degree in Political Research.
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... Las investigaciones informan que los adolescentes TGNC tienen un alto riesgo de padecer otras comorbilidades psicopatológicas en relación con sus pares cisgénero, entre las que se encuentran síntomas de ansiedad, síntomas depresivos, ideación suicida, intentos de suicidio, trastornos de la alimentación, trastornos de la personalidad, Trastorno del Espectro Autista (TEA), Trastorno de Estrés Postraumático (TEPT), Trastornos de la Atención con Hiperactividad (TDAH) y abuso en consumo de sustancias (Bauer et al., 2021;Becerra et al., 2018;Bonifacio et al., 2019;Chen et al., 2021;Guss et al., 2015;Holt et al., 2016;Kaltiala et al., (2020); Kyriakou et al., 2020;Mahfouda et al., 2017;Modrego et al., 2021;Rider et al., 2018;Sevilla et al., 2019;Toomey et al., 2018). ...
... Los resultados indicaron que la disforia de género, así como, otros problemas de salud mental asociados a la manifestación de la identidad de género, en la mayoría de los casos se debe a la discriminación, victimización, estigmatización, acoso y rechazo que experimentan tanto en el entorno familiar como en la escuela. (Bauer et al., 2022;Becerra et al., 2018;Chodzen et al., 2018;Holt et al., 2016;Modrego et al., 2021;Peng et al., 2019, Rider et al., 2018. Lo que pone de manifiesto la urgencia de cambios sociales que promuevan la aceptación, visibilidad, integración y seguridad de las personas con identidades y expresiones de género no normativas en todos sus contextos vitales. ...
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... Of the four studies conducted with clinical samples, it was often unclear how certain constructs were measured, as the data were often based on case files, referral letters, and clinical notes. Holt et al. 37 mention that participants had features of gender dysphoria but do not specify whether this was based on any diagnostic criteria, clinician assessment/case notes, or reported by the patient. Kozlowska et al. 38 report using clinical assessment to examine gender dysphoria, but it was not clear what criteria are used in this assessment. ...
... Kozlowska et al. 38 report using clinical assessment to examine gender dysphoria, but it was not clear what criteria are used in this assessment. In Holt et al. 37 and Petruzzelli et al., 39 it was not clear how self-injury or self-harm was operationalized in clinical notes; however, as each of the studies differentiated between self-injury/harm and suicidality, we chose to include these studies. Among the qualitative studies, there were other methodological limitations. ...
... Four studies looked at the role of gender dysphoria in NSSI. [37][38][39]43 Three of these looked at the rates of self-injury in young people attending gender clinics with a diagnosis or features of gender dysphoria and found that 39-52.6% had a history of self-injury or self-harm. [37][38][39] The behavior was also more common among clients who were assigned female at birth, as well as among 12-18 year olds compared with 5-11 year olds. ...
... An alternative view sees GD as a dimensional construct, with individuals demonstrating varying degrees of GD feelings that can be measured using continuous selfreported measures [12,14,44]. There has been increased research into the relationship between autism and gender dysphoria (GD) following international reports of an overrepresentation of autistic individuals within gender clinics [8,13,27,33,38]. Studies have reported that up to 26% of people attending gender clinics for a suspected diagnosis of GD also have a diagnosis of autism [33,41]. ...
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Background Research has demonstrated a strong relationship between autism and gender dysphoria (GD) and that this relationship could be explained by obsessional interests which are characteristic of autism. However, these studies often measured obsessions using either single items which questions the reliability of the findings, or within autistic trait measures meaning the findings may simply index a more general relationship between autistic traits and GD. Therefore, the present study aimed to investigate the relationships between obsessional thoughts and traits of GD using a measure of obsessional thoughts alongside a measure of autistic traits, which was investigated in both non-clinical and clinical samples. Methods A total of 145 non-clinical participants took part in Study 1 and all completed the Autism-Spectrum Quotient (AQ) as a measure of autistic traits, the Obsessive-Compulsive Inventory-Revised (OCI-R) obsessional thoughts subscale as a measure of obsessional thoughts, and the Gender-Identity/Gender-Dysphoria Questionnaire (GIDYQ) to measure traits of GD. For Study 2, a total of 226 participants took part in Study 2 and all completed the same measures as in Study 1. They included participants diagnosed with GD (N = 49), autism (N = 65), OCD (N = 46) and controls with no diagnosis (N = 66). Results The hierarchical linear regression for Study 1 showed that both total AQ and OCI-R obsessional thoughts scores were uniquely associated with GIDYQ scores, with no interaction effect between the scores. The results for Study 2, from a hierarchical linear regression, once again found that obsessional thoughts and autistic traits were each uniquely associated with GIDYQ scores, but not their interaction. The GD and autistic groups both reported significantly greater traits of GD than the OCD and control groups, with the GD group reporting higher scores than the autistic group. Limitations Participants self-reported their diagnoses for Study 2, but diagnostic tests to verify these were not administered. Traits of GD were also measured at a single point in time, despite such traits being transient and continuous. Conclusions The results show both obsessional thoughts and autistic traits are uniquely associated with GD, and that autistic people experience greater traits of GD than other clinical groups.
... Effective communication in this study enabled one adolescent participant to express their anxiety and gender incongruence which in turn enhanced their relationships, providing emotional relief and an increase in school performance. Similarly to allistic TGD people, supporting autistic TGD individuals to explore gender more flexibly was suggested as one way to alleviate distress and deconstruct the gender binary (Holt et al., 2016). However, it was noted that social transitioning can either be a source of anxiety, complicated by social differences, or an easy step in the transition journey (Bouzy et al., 2023). ...
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... 1 Further, those referred were increasingly presenting with co-occurring autistic spectrum condtions 6 and mental health conditions. [7][8][9] Second, concerns about the quality of care offered had been raised. In 2020 an inspection by the Care Quality Commission (CQC), despite rating GIDS 'good' for care-with families reporting that clinicians treated them with compassion and kindness, respected their privacy and dignity, and understood their needs-gave an overall rating of 'inadequate', with significant improvements required in risk management, record keeping (including recording consent) and leadership. ...
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... Gender-dysphoric adolescents often have psychiatric comorbidities such as depression and/or anxiety disorder [39][40][41]. Some cases of school refusal seem to be related to GD, especially in junior high school and high school. ...
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... Pudimos observar que las personas AMN presentaron una mayor vulnerabilidad psicológica determinada por autolesiones, ideación suicida e intentos de suicidio. Estas diferencias fueron reportadas previamente en múltiples investigaciones en las que se observó que las personas AMN presentan mayor riesgo de autolesiones, ideas suicidas e intentos de suicidio que las AVN (Arcelus et al., 2015;de Graaf et al., 2022;Fisher et al., 2017;Hartig et al., 2022;Holt, Skagerberg, & Dunsford, 2016;Miranda-Mendizabal et al., 2019;Newcomb et al., 2020;Ream, 2019;Rood, Puckett, Pantalone, & Bradford, 2015;Thoma et al., 2019;Toomey, Syvertsen, & Shramko, 2018). Esta mayor tendencia a riesgo de autolesiones y suicida podría ser explicada en parte por las diferencias biológicas y hormonales y porque a pesar de que las personas AVN suelen tener mayor estigmatización, que se observa por el mayor antecedente de haber sufrido bullying, las personas AMN tendrían mayores dificultades para lidiar con la angustia provocada por su imagen corporal, como fue demostrado previamente (Fisher et al., 2017). ...
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Introducción: Las personas transgénero sufren de discriminación y estrés de las minorías y con frecuencia reportan altos índices de vulnerabilidad psicológica. El objetivo de esta investigación fue evaluar la situación psicosocial de las personas trans que consultaron al Servicio de Diversidad y los factores involucrados en el riesgo de suicidalidad. Material y métodos: Se recabaron en forma retrospectiva datos demográficos y de vulnerabilidad psicológica de las historias clínicas de 934 personas trans de las cuales 359 fueron asignados varón al nacer y 575 asignados mujer al nacer. Resultados y conclusiones: Las personas asignadas mujer al nacer consultaron a una edad menor y reportaron una mayor frecuencia de bi/pansexualidad. Resultados: Se reportó un 33,1 % de abuso sexual, 63,3 % de bullying, 40,9 % de autolesiones, 52,7 % de ideación suicida y 25,2 % de intentos de suicidio, siendo las personas asignadas mujer al nacer, las que presentaron la mayor frecuencia de vulnerabilidad psicológica. En el análisis de regresión logística, las variables asociadas a mayor riesgo de autolesiones y suicidalidad fueron: la menor edad, la orientación bi/pansexual, ser asignado mujer al nacer, el antecedente de abusos y bullying. Conclusión: Por todo esto se hace necesario elaborar programas de acompañamiento y prevención del riesgo suicida en esta población.
... However, Chew et al. [27], based on one study [36], reported significantly higher levels of anxiety and depression in non-binary adolescents compared to binary transgender youth, whereas our metaanalysis found no significant differences between these groups. This does not imply that non-binary individuals are unaffected, as both non-binary and transgender youth generally exhibit higher levels of anxiety and depression compared to cisgender individuals [67][68][69][70]. Thus, the similar rates between non-binary and transgender youth in our analysis suggest a greater impact on non-binary youth relative to cisgender peers. ...
Article
Full-text available
Background Non-binary identities are increasingly recognized within the spectrum of gender diversity, yet there is a dearth of research exploring the mental health challenges specific to this population. Therefore, this systematic review and meta-analysis aimed to comprehensively assess the mental health outcomes of non-binary youth in comparison to their transgender and cisgender peers. Methods A systematic search was conducted to identify relevant studies across three electronic databases (PubMed, Scopus, Web of Science) covering the period from inception to October 2023. The meta-analysis was performed employing a random-effects model. Inclusion criteria encompassed studies comparing non-binary youth with transgender or cisgender youth, providing data on mental health outcomes such as general mental health, depressive and anxiety symptoms, self-harm and suicidality. Results Twenty-one studies, meeting the inclusion criteria and originating from six different countries, were included in the analysis. The sample encompassed 16,114 non-binary, 11,925 transgender, and 283,278 cisgender youth, with ages ranging from 11 to 25 years. Our meta-analysis revealed that non-binary youth exhibit significantly poorer general mental health compared to both transgender (d = 0.24, 95% CI, 0.05–0.43, p =.013) and cisgender youth (d = 0.48, 95% CI, 0.35–0.61, p <.001), indicating a more impaired general mental health in non-binary youth. Regarding depressive symptoms, when comparing non-binary and cisgender individuals, a moderate and significant effect was observed (d = 0.52, 95% CI, 0.41–0.63, p <.001). For anxiety symptoms, a small but significant effect was observed in the comparison with cisgender individuals (d = 0.44, 95% CI, 0.19–0.68, p =.001). Furthermore, non-binary individuals exhibited lower rates of past-year suicidal ideation than transgender peers (OR = 0.79, 95% CI, 0.65–0.97, p =.023) and higher rates of lifetime suicidal ideation than cisgender youth (OR = 2.14, 95% CI, 1.46–3.13, p <.001). Conclusion Non-binary youth face distinct mental health challenges, with poorer general mental health, elevated depressive and anxiety symptoms compared to cisgender, and similar rates of self-harm and suicidal behavior compared to transgender individuals. These findings underscore the urgent need for targeted interventions, including gender-affirming mental health support, to address the specific needs of non-binary youth.
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This scoping review was focused on the associations between autism and gender diversity from an intersectional perspective. The scoping review aimed to answer the following five research questions: (1) What percentage of studies that examine the co-occurrence between autism and gender diversity are based on quantitative, qualitative, or mixed methods research? (2) What theoretical models are used to improve understanding of this relationship? (3) How often do these studies employ an intersectional perspective in the examination of autism and gender identity? (4) How many studies use participants with lived experiences and/or consider perspectives of children, young people, and adults in their methodology? (5) How often do these studies acknowledge the importance of online spaces? The current scoping review found 29 studies that (1) were predominantly quantitative, (2) focused mainly on children and adolescents, and (3) explained the co-occurrence between autism and gender diversity using a broad range of bio-psycho-social variables. The main gaps identified in this scoping review were (1) the need to conduct future mixed-method research that is co-produced by autistic and gender diverse individuals; (2) the importance of working with autistic and gender diverse individuals from intersectional, neurodiverse, and gender diverse affirmative approaches in clinical, educational, and research settings; and (3) how online environments could potentially be used by autistic and gender diverse people to express their own identity throughout their lives.
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This paper presents findings of a detailed service audit of cases seen at a specialist service for children and adolescents with gender identity disorders. The audit looked at clinical features, associated features, demographic characteristics and complexity of the cases. Data were extracted from patient files of the first 124 cases seen by the service. Clinical features were assessed based on DSM-IV criteria (American Psychiatric Association, 1994) and associated features were based on the clinical features list of the Association of Child Psychology and Psychiatry (ACPP) data set (Berger et al., 1993). A range of results is presented documenting the occurrence and frequency of different clinical features at different ages. These include the finding that stereotypically gendered clothing (i.e. boys cross-dressing and girls refusing to wear skirts) is more significant in pre-pubertal children, whereas dislike of bodily sexual characteristics becomes more predominant in post-pubertal children. The most common associated features were relationship difficulty with parents/carers (57%), relationship difficulty with peers (52%) and depression/misery (42%). Gender identity problems have wide-reaching implications for children and their families and problems may become more entrenched with the onset of puberty. Although specialist support and co-ordination of services becomes essential particularly at this time, interventions in childhood may have the function of preventing difficulties becoming more severe during adolescence. http://web.archive.org/web/20070525044205/http://www.symposion.com/ijt/ijtvo06no01_01.htm
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Background: Recent studies have highlighted the co-occurrence of gender dysphoria (GD) in adolescence and Autistic Spectrum Conditions (ASC). Systemising and empathising are two psychological dimensions linked to ASC. People with ASC score below average on the Empathy Quotient (EQ) and average or above average on the Systemising Quotient (SQ). Based on the results of previous studies we predicted that if the young people with GD shared aspects of the ‘broader autism phenotype’, their EQ would be lower, and their SQ would be the same or higher, compared to controls of their natal gender. Methods: This preliminary study examined systemising and empathising in adolescents with GD using parent report questionnaires. 35 parents of adolescents with GD aged 12-18 attending the Gender Identity Development Service (London) took part. Parents of 156 typically developing adolescents aged 12-18 were used as a control group. The parents were asked to complete the Adolescent EQ and SQ. Results: The mean EQ score of both the female-to-male, and male-to-female GD group was found to be significantly lower than typically developing females, but similar to that of control males. There was no significant difference on the SQ between the gender dysphoric groups and either female or male controls. Conclusion: This study shows that on average adolescents with GD, specifically those who are female-to-male, have lower empathy than controls. For this group of adolescents it may be helpful to offer psychological interventions that improve their communication skills and their ability to take on board other people’s views, to support their development. This may enable them to make better informed decisions regarding treatment and physical intervention options during adolescence and beyond.
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This article presents the findings from an audit on self-harm in 125 children and adolescents referred to the Gender Identity Development Service in London. Data concerning selfharming thoughts and behaviors before attending the service were extracted from documents in the patient files and from clinician reports. The findings indicated that suicide attempts and self-harming were more common over the age of 12. Overall, thoughts of self-harm were more common in the natal males whereas actual self-harm was more common in the natal females. The number of suicide attempts did not differ significantly between the two genders. The implications of these findings are discussed. Limitations of the study are also discussed which include that the data was only collected over an 8-month period and that it was extracted from patient files and from clinician reports.
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The aim of the current paper was to examine externalizing and internalizing behaviors in adolescents with gender dysphoria. One hundred forty-one young people (84 natal females and 57 natal males, M age = 15.13, SD = 1.70) attending the Gender Identity Development Service in London completed the Youth Self Report form at the end of the assessment period (4 to 6 sessions). The main findings indicated that, overall, the adolescents showed significantly more internalizing than externalizing behaviors. Using cutoff points provided by Achenbach and Rescorla (2001), the mean internalizing score fell within the clinical range and the mean externalizing score within the normal range. There was also a significant positive relationship between these two behaviors both in the natal females and the natal males. The natal males presented with significantly more internalizing behaviors than the natal females; however, no significant difference was observed between the genders in terms of the number of externalizing behaviors and total problems. We discuss the implications of these findings with regard to clinical work.
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For gender dysphoric children and adolescents, the school environment may be challenging due to peer social ostracism and rejection. To date, information on the psychological functioning and the quality of peer relations in gender dysphoric children and adolescents has been studied via parental report, peer sociometric methods, and social interactions in laboratory play groups. The present study was the first cross-national investigation that assessed behavior and emotional problems and the quality of peer relations, both measured by the Teacher's Report Form (TRF), in a sample of 728 gender dysphoric patients (554 children, 174 adolescents), who were referred to specialized gender identity clinics in the Netherlands and Canada. The gender dysphoric adolescents had significantly more teacher-reported emotional and behavioral problems than the gender dysphoric children. In both countries, gender dysphoric natal boys had poorer peer relations and more internalizing than externalizing problems compared to the gender dysphoric natal girls. Furthermore, there were significant between-clinic differences: both the children and the adolescents from Canada had more emotional and behavioral problems and a poorer quality of peer relations than the children and adolescents from the Netherlands. In conclusion, gender dysphoric children and adolescents showed the same pattern of emotional and behavioral problems in both countries. The extent of behavior and emotional problems was, however, higher in Canada than in the Netherlands, which appeared, in part, an effect of a poorer quality of peer relations. Per Bronfenbrenner's (American Psychologist, 32, 513-531, 1977) ecological model of human development and well-being, we consider various interpretations of the cross-national, cross-clinic differences on TRF behavior problems at the level of the family, the peer group, and the culture at large.
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