Article

Production of (R)-1-phenylethanols Through Bioreduction of Acetophenones by a New Fungus Isolate Trichothecium roseum

Faculty of Sciences, Department of Chemistry, Ataturk University, Erzurum 25240, Turkey.
Chirality (Impact Factor: 1.89). 06/2010; 22(6):543-7. DOI: 10.1002/chir.20775
Source: PubMed

ABSTRACT

A total of 120 fungal strains were isolated from soil samples and evaluated in the bioreduction of substituted acetophenones to the corresponding (R)-alcohols. Among these strains, isolate Trichothecium roseum EBK-18 was highly effective in the production of (R)-alcohols with excellent enantioselectivity (ee > 99%). Gram scale preparation of (R)-1-phenylethanol is reported.

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