Fine needle aspiration cytology of oncocytic lipoadenoma of the parotid gland: Report of a rare case

ArticleinActa cytologica 53(4):437-9 · July 2009with12 Reads
Source: PubMed
Abstract
Oncocytic lipoadenoma is an uncommon benign salivary gland tumor. There are only rare case reports of this distinct entity in which only the histopathologic aspects are discussed. Fine needle aspiration cytologic (FNAC) findings of oncocytic lipoadenoma have not yet been documented. A 50-year-old woman presented with a slow-growing swelling in the left parotid region that was clinically interpreted as a soft tissue tumor, with a differential of neurofibroma/lipoma. FNAC showed moderate cellularity, with oncocytic cells arranged predominantly as microacini in a prominent lipoid background. The adipose tissue background of the cytologic smears was ignored as material derived from the normal fat tissue; based on the oncocytic population of cells, a diagnosis of oncocytoma was considered. A remote possibility of acinic cell carcinoma with oncocytic features was also suggested. However, histopathologic examination showed it to be an oncocytic lipoadenoma, a tumor we were unaware of at the time of cytodiagnosis. Both cytopathologists and histopathologists need to be aware of oncocytic lipoadenoma of the salivary gland in order to diagnose it precisely. The clinicocytopathologic correlation highlighted in our case will be useful for cytopathologists in preoperative interpretation and diagnosis.
  • Article · Jul 2009
  • [Show abstract] [Hide abstract] ABSTRACT: Background Pleomorphic adenoma with extensive lipometaplasia is a rare, benign tumor of salivary gland origin. To the best of our knowledge, the fine needle aspiration cytologic features of this distinct morphologic entity have not been documented before. Case A 49-year old male presented with right-sided parotid swelling that was clinically diagnosed as a pleomorphic adenoma. Fine needle aspiration yielded sticky, fatty material; the smears showed features of pleomorphic adenoma with intimately associated, abundant adipose tissue elements. A cytodiagnosis of pleomorphic adenoma with extensive lipometaplasia was rendered and confirmed by histopathologic examination. Conclusion Pleomorphic adenoma with extensive lipometaplasia is an unusual benign salivary gland tumor with distinct histomorphology Cytologically, it is characterized by the presence of an excessive amount of intimately associated adipose tissue in an otherwise-classic pleomorphic adenoma. (Acta Cytol 2009;53:457-459)
    Full-text · Article · Jul 2009
  • [Show abstract] [Hide abstract] ABSTRACT: Pleomorphic adenoma with extensive lipometaplasia is a rare, benign tumor of salivary gland origin. To the best of our knowledge, the fine needle aspiration cytologic features of this distinct morphologic entity have not been docnmented before. A 48-year-old male presented with right-sided parotid swelling that was clinically diagnosed as a pleomorphic adenoma. Fine needle aspiration yielded sticky, fatty material; the smears showed features of pleomorphic adenoma with intimately associated, abundant adipose tissue elements. A cytodiagnosis of pleomorphic adenoma with extensive lipometaplasia was rendered and confirmed by histopathologic examination. Pleomorphic adenoma with extensive lipometaplasia is an unusual benign salivary gland tumor with distinct histomorphology. Cytologically, it is characterized by the presence of an excessive amount of intimately associated adipose tissue in an otherwise-classic pleomorphic adenoma.
    Article · Jul 2009
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