Article

Basic Science and Clinical Aspects of Achilles Tendinopathy

Department of Trauma and Orthopaedic Surgery, University Hospital Wales, Heath Park Cardiff, UK.
Sports medicine and arthroscopy review (Impact Factor: 1.68). 10/2009; 17(3):190-7. DOI: 10.1097/JSA.0b013e3181b37eb7
Source: PubMed

ABSTRACT

Achilles tendinopathy is one of the common disorders seen in athletes. It is a degenerative rather than an inflammatory, condition. There is a lifetime risk of 52% in former elite male distance runners. This condition is difficult to manage and up to 29% of Achilles tendinopathy patients may require surgery. It often results in chronic pain and discomfort along with failure to regain full function. It can be complicated by partial tears or complete rupture causing long-term burden on healthcare system and making treatment quite difficult.

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Available from: Nicola Maffulli, Apr 03, 2014
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    • "It is expressed that tendon ruptures occur more in males due to the fact that calcaneal tendon is of a rigid character in them (Doral et al., 2010). Besides, it is stated in studies that achilles tendinopathy occurs commonly in athletes (Zafar et al., 2009). It is pointed out that there is a 52% of risk for tendinopathy, particularly in the long-distance male runners throughout their lives (Zafar et al.). "
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    • "In the knee area a typical formation of patellofemoral syndrome known as " runner's knee " or patellar tendinitis known as " jumper's knee " and some forms of bursitis could occur. In the shank and foot area we could find a presence of medial tibial stress syndrome and frequent injuries of Achilles tendon (Alfredson, 2003; Järvinen, Kannus, Maffulli, & Khan, 2005; Maffulli, Sharma, & Luscombe, 2004; Zafar, Mahmood, & Maffulli, 2009). For example de Vos et al. (2010) found out that up to 52% of endurance runners hurt their Achilles tendon sometime during their career. "
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    • "Despite some advancements in the management of acute and chronic tendinopathies, several aspects related to the pathophysiology of human tendons remain largely unclear [1]–[3]. Tendon cells, residing between fibril components mainly represented by collagens and proteoglycans, synthetize extracellular matrix (ECM) [4]–[6]. "
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