The majority of drugs used to treat cancer today were originally isolated from natural products. Currently, anticancer properties were reported in much more than 3000 plants across the world. The prevalence of using products made from plants to treat cancer ranges from 10% to 40% globally, reaching 50% in patients from Asia. The most important source has been the kingdom of plants. Podophyllum lignans, Taxus diterpenes, camptotheca alkaloids, and vinca alkaloids are a few of these. Ayurvedic medications now contain pharmacologically active ingredients, and researchers are evaluating their potential for use in drug therapy. Nearly 3000 of the 17,000 species that have been discovered are thought to be used in medicine. For these different types of plants are searched and discussed where cardamom and walnut are found as antiproliferative agents. Cardamom is traditionally known as the “Queen of Spices.” There are generally two types of cardamom, big cardamom and small cardamom, and they have been used in India as a spice since ancient times and also used in medicine such as cancer and, in addition, antioxidant, stomachic, or windiness. Cardamom is frequently used tinctures; used as a carminative, diuretic, stomachic, and stimulant with a strong, pleasant aroma. Cardamom use prevents vomiting and nausea, which contains server types of phytoconstituents such as Methyl eugenol, geraniol, sabinene, β-pinene, α-pinene, myrcene, 1,8, cineole, terpinolene, trans-nerolidol, nerol, citronellol, α-terpinyl acetate, and α-terpineol. Black walnut (Juglans nigra) and English walnut (Juglans regia) are types of walnuts. Walnut is a plant which is important for human health; it contains many nutrients such as alkaloids, carbohydrates, iron, protein, phosphorus, vitamin C, and vitamin E present in Juglans nigra walnut. Walnuts contain different types of chemical components in different parts, which are shown in the table given below. Walnuts have an antiproliferative effect.