From sleep duration to mortality: Implications of meta-analysis and future directions: Editorial

Journal of Sleep Research (Impact Factor: 3.35). 07/2009; 18(2):145-7. DOI: 10.1111/j.1365-2869.2009.00753.x
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Available from: Michael Grandner
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    • "Recently, Gallicchio and Kalesan [24] in a systematic review/meta-analysis identified that people with both short and longer periods of sleep are at an increased risk of all-cause mortality. However, the actual pathway by which sleep is linked to cardiovascular complications [25] is not clear, although it is plausible to believe that a pathway exists. Adolescents are prone to perform more activities at night (TV viewing and computer usage) than children and thus they are more exposed to shorter periods of sleep. "
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    ABSTRACT: Background: In pediatric populations, the use of resting heart rate as a health index remains unclear, mainly in epidemiological settings. The aims of this study were to analyze the impact of resting heart rate on screening dyslipidemia and high blood glucose and also to identify its significance in pediatric populations. Methods: The sample was composed of 971 randomly selected adolescents aged 11 to 17 years (410 boys and 561 girls). Resting heart rate was measured with oscillometric devices using two types of cuffs according to the arm circumference. Biochemical parameters triglycerides, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and glucose were measured. Body fatness, sleep, smoking, alcohol consumption and cardiorespiratory fitness were analyzed. Results: Resting heart rate was positively related to higher sleep quality (β = 0.005, p = 0.039) and negatively related to cardiorespiratory fitness (β = −0.207, p = 0.001). The receiver operating characteristic curve indicated significant potential for resting heart rate in the screening of adolescents at increased values of fasting glucose (area under curve = 0.611 ± 0.039 [0.534 – 0.688]) and triglycerides (area under curve = 0.618 ± 0.044 [0.531 – 0.705]). Conclusion: High resting heart rate constitutes a significant and independent risk related to dyslipidemia and high blood glucose in pediatric populations. Sleep and cardiorespiratory fitness are two important determinants of the resting heart rate,
    Full-text · Article · Apr 2013 · BMC Pediatrics
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    • "Sleep complaint and daytime tiredness are associated with obesity Numerous studies have found that short sleep duration is a significant predictor of BMI (Grandner et al. 2010b; Chaput et al. 2009b; Must and Parisi 2009; Grandner and Patel 2009), and the findings from laboratory studies have also supported this (Nedeltcheva et al. 2009). Studies in the sleep apnea literature have found significant relationships between sleep fragmentation (due to respiratory events) and daytime sleepiness and fatigue (Yue et al. 2009). "
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    ABSTRACT: Aim Previous studies have demonstrated relationships between sleep and both obesity and diabetes. Additionally, exercise may improve sleep and daytime function, in addition to weight and metabolic function. The present study extends these findings by examining how general sleep-related complaints are associated with body mass index (BMI), diabetes diagnosis, and exercise in a large, nationally representative sample. Subject and methods Participants were respondents to the Behavioral Risk Factor Surveillance System (BRFSS). Sleep complaint (SC) was measured with “Over the last 2 weeks, how many days have you had trouble falling asleep or staying asleep or sleeping too much?” Daytime complaint (DC) was measured with “Over the last 2 weeks, how many days have you felt tired or had little energy?” Responses were dichotomized, with ≥6 days indicating complaint. Covariates included age, race/ethnicity, income, and education. Results Being overweight was associated with DC in women only. Obesity was significantly associated with SC and DC in women, and DC in men. Diabetes was associated with SC and DC in both genders. Any exercise in the past 30 days did not attenuate any BMI or diabetes relationships, but was independently associated with a decrease in SC and DC in both men and women. Conclusion These results suggest that for both men and women diabetes is a significant predictor of sleep and daytime complaints, and there is a relationship between obesity and sleep and complaints for women to a greater extent than men. Finally, exercise was associated with much fewer sleep and daytime complaints in both genders.
    Full-text · Article · Oct 2011 · Community Medicine
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    • "The annual number of papers bearing the words Ôsleep durationÕ as part of the title increased from approximately three per year in the 1990s to more than 50 in 2008. These investigated the relationship between self-reported sleep duration and a large number of health-related conditions such as diabetes, cardiovascular morbidity, hypertension, metabolic syndrome and obesity, cancer, psychiatric disorders, neurological disorders and mortality (see a recent meta-analysis on the relationship between mortality and self-reported sleep duration and an accompanying editorial in Gallicchio and Kalesan, 2009; Grandner and Patel, 2009). Generally, both short sleep (<6 h) or long sleep (>8 h) were associated with detrimental health-related effects. "

    Full-text · Article · Dec 2009 · Journal of Sleep Research
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