Conference Paper

Efficacy of Sodium Bicarbonate Toothpastes on Gingivitis and Plaque

To read the full-text of this research, you can request a copy directly from the authors.


Objective: To evaluate the efficacy of 67%w/w and 62%w/w sodium bicarbonate toothpastes on gingivitis and dental plaque control compared to a control toothpaste (0% sodium bicarbonate). Method: This was a single-centre, randomized, examiner blind, three treatment, parallel group, stratified design. Following informed consent and screening there was a 1-2 week washout period. Following baseline examinations and dental prophylaxes, subjects were randomized to one of three treatment groups (67%, 62% or 0% sodium bicarbonate). They then brushed twice daily for one timed minute for 12 weeks with their randomized toothpaste at home. Examinations using the Gingival Index (GI) and Turesky Plaque Index (TPI) were performed after 6 and 12 weeks. Gingivitis Severity Index (GSI) was calculated based on GI score. GI, TPI and GSI were compared between treatments using analysis of covariance (ANCOVA). Result: Three hundred and thirty-six subjects were included in the efficacy analysis. Relative to the 0% sodium bicarbonate control toothpaste group the 67% sodium bicarbonate toothpaste exhibited statistically significant reductions in GI of 4.76%, TPI of 7.73% and GSI of 23.64% after 12 weeks, respectively. Relative to the 0% sodium bicarbonate control toothpaste group the 62% sodium bicarbonate toothpaste exhibited a non signficant reduction in GI of 2.15% and GSI of 12.50%, respectively. However, the 62% sodium bicarbonate toothpaste compared to the 0% sodium bicarbonate toothpaste and exhibited statistically significant reductions in plaque of 6.47% after 12 weeks. Conclusion: The results of the present clinical study demonstrate that the use of 67% sodium bicarbonate toothpaste over a 12 week period provides statistically significant superior gingivitis and plaque control to a 0% sodium bicarbonate control toothpaste.

No full-text available

Request Full-text Paper PDF

To read the full-text of this research,
you can request a copy directly from the authors.

ResearchGate has not been able to resolve any citations for this publication.
Dentifrices traditionally have been formulated as pastes or gels. However, liquid varieties recently have become available The authors conducted a study to determine whether a fluoridated liquid product with added triclosan and a polyvinyl methyl ether/maleic acid, or PVM/MA, copolymer delivery system is efficacious for the control of supragingival plaque and gingivitis. The authors conducted a six-month, double-blind, parallel, stratified clinical study in accordance with American Dental Association guidelines for the clinical evaluation of antiplaque/antigingivitis products. Subjects who qualified with a suitable amount of existing plaque and gingivitis were given one of two dentifrices: an "experimental" liquid dentifrice containing 0.3 percent triclosan, 2.0 percent PVM/MA copolymer and 0.243 percent sodium fluoride, or NaF, in a silica base; or a "placebo" dentifrice containing 0.243 percent NaF in a silica base. The authors collected subjects' plaque and gingival index scores at baseline, three months and six months. The results of the study indicate that the use of the experimental liquid dentifrice provided a significant reduction in existing levels of plaque and gingivitis as compared with the placebo standard dentifrice. At six months, the experimental group demonstrated a 34.9 percent reduction in plaque formation and a 25.7 percent reduction in gingivitis as compared with the placebo group (P < .001). When compared with the placebo, the experimental dentifrice had a significantly better ability to reduce plaque and gingivitis. When compared with results reported in the literature, this new form of dentifrice achieved results comparable in efficacy to those of traditional dentifrice pastes with matching active ingredients. This study confirms that a liquid dentifrice containing a triclosan/copolymer/NaF delivery system is efficacious in its ability to reduce existing plaque and gingivitis.
The purpose of this paper is to discuss the changed trends of population, oral diseases and their effects on Chinese dentistry. The demographic and epidemiologic data published in recent books and journals were reviewed and analyzed. As the 21st century approached, dentistry in China would face many changing trends and challenges. 1. a growing population and an aging population: The two sub-populations with the greatest need for prevention and treatment were children and old patients who were outpacing the supply of dental manpower. 2. The changed dental disease patterns: The prevalence of caries was increasing and more than two thirds of Chinese suffered from periodontal disease. The traditional dental approaches have not been able to satisfy the needs of Chinese. The challenge created by these demographic, economic and advances in dental technology is changing Chinese dentistry.
Report of the third national oral health survey in China
  • X Qi
Qi, X. Q. "Report of the third national oral health survey in China". People's Medical Publishing House (2008): 11-12.