Conference Paper

Efficacy of Sodium Bicarbonate Toothpastes on Gingivitis and Plaque

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Abstract

Objective: To evaluate the efficacy of 67%w/w and 62%w/w sodium bicarbonate toothpastes on gingivitis and dental plaque control compared to a control toothpaste (0% sodium bicarbonate). Method: This was a single-centre, randomized, examiner blind, three treatment, parallel group, stratified design. Following informed consent and screening there was a 1-2 week washout period. Following baseline examinations and dental prophylaxes, subjects were randomized to one of three treatment groups (67%, 62% or 0% sodium bicarbonate). They then brushed twice daily for one timed minute for 12 weeks with their randomized toothpaste at home. Examinations using the Gingival Index (GI) and Turesky Plaque Index (TPI) were performed after 6 and 12 weeks. Gingivitis Severity Index (GSI) was calculated based on GI score. GI, TPI and GSI were compared between treatments using analysis of covariance (ANCOVA). Result: Three hundred and thirty-six subjects were included in the efficacy analysis. Relative to the 0% sodium bicarbonate control toothpaste group the 67% sodium bicarbonate toothpaste exhibited statistically significant reductions in GI of 4.76%, TPI of 7.73% and GSI of 23.64% after 12 weeks, respectively. Relative to the 0% sodium bicarbonate control toothpaste group the 62% sodium bicarbonate toothpaste exhibited a non signficant reduction in GI of 2.15% and GSI of 12.50%, respectively. However, the 62% sodium bicarbonate toothpaste compared to the 0% sodium bicarbonate toothpaste and exhibited statistically significant reductions in plaque of 6.47% after 12 weeks. Conclusion: The results of the present clinical study demonstrate that the use of 67% sodium bicarbonate toothpaste over a 12 week period provides statistically significant superior gingivitis and plaque control to a 0% sodium bicarbonate control toothpaste.

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