Parvovirus B19 is a ubiquitous virus typically limited to the pediatric population as erythema infectiosum or "fifth disease." In the adult populations, symptomatic Parvovirus infections can be seen in the setting of immunosuppression associated with transplant. These patients generally respond well to reduction in immunosuppression and IVIg, and do not require extended therapy. We present an interesting case of a renal transplant patient, who developed a chronic Parvovirus B19 infection after receiving a cadaveric kidney transplant. His case was additionally complicated by the diagnosis of hemochromatosis that required treatment with deferasirox due to the anemia from chronic parvovirus infection.