Comparing the efficacy of dates and oxytocin in the management of postpartum hemorrhage

Article (PDF Available)inShiraz E Medical Journal 8(2):64-71 · April 2007with 2,651 Reads
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Abstract
Introduction: The aim of study was a comparison between dates and oxytocin in prevention of postpartum haemorrhage. In modern obstetrics, general trend to utilize non-aggressive treatment methods that is quite safe, cheap and few symptoms. Date fruit has Calcium, serotonin, tannin, glucose that they are important for bleeding control. Materials and Methods: This study was performed in Imam Reza and Hazrat Zainab Hospitals, Mashhad University of Medical Science. It was clinical trial that was performed on 62 women delivered in hospital. Immediately after placental delivery, 50 gram oral Deglet Noor dates (group 1) and 10 unit of intramuscular oxytocin (group 2) were given. At the same time a Plastic and a cotton sheet were widen under the patients and a pad was placed on the perineum to absorb blood or fluid. All pads were collected until 3 hour after placental delivery and were weighed every one hour. The difference, before and after weight was calculated.( 100 gram increase in weight was considered to be equivalent to 100 ml blood). Result: Blood loss mean in the end of first hour after delivery were significantly different in dates and oxytocin groups (104 ml vs. 141.6 ml, p=0.043), But in second and third hour were not significant, although the bleeding in dates group was less. In whole three hours after delivery the blood loss mean in dates group was significantly less than oxytocin group (162.5 ml vs. 220.7, p=0.02). Conclusions: Use of oral dates after delivery decreases bleeding more than intramuscular oxytocin and it´s a good alternative in normal delivery. Key Words: postpartum haemorrhage, oxytocin, dates

In the name of God
Department of Internal Medicine
Shiraz E-Medical Journal
Vol. 8, No. 2, April 2007

Comparing the Efficacy of Dates and Oxytocin in the Management of
Postpartum Hemorrhage.
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<!"    !   3F 235
B<!
+!
 2=5) < (
"   " <  !
  !26(45.
) G! ! #" 
< "  ! ! 
4>>       =7 <
<23485 $ < (
"  <  < 
 <    <
48 +< +" & 
+ +<    :+ :
 235&<  A(
  < ! !  !&
!!   306>    
<!!&+!<
!A!
  "  !& < ! (
& <   ! ! 
!&2@15
!  <
!!!&3>F
8F   +   <  
7>F 205 < < A  
!  !  "
+ & "   
+&  !!  
&  <! + A
 + !  !
 &    ! 
B<!!&  !+(< "
275.#<<!!:"
 A    +  (
3><!!<(
<"!!
!& + +!  20333=5. (
 <  A  (
 < ! ! "
H  &< !<  3>
<  A : !!  !
! < +   "<
!!   + &!
!  "  + 
  285 H  
< " + + (
&  !   (
: "   !! (
 205 9! <!  
!A!<&(
    &" &A 
<  !<  <
<"36    "!
 <!(""&
   B<   
+  "   (
<  $  ! 
$ 9<  "&"  
!!&
 !&   $ 2 
<5&==(=8 $<
    
I +
!& 2375
&   + < 
<!  <  < <
  &!!  +< (
&  !  !  +
:    <   
"  < "
<-
3( . <  ,!< 
 !!    (
!"
! =(. <  < "!<
      < 
65

<  "    ! 
     <!  <<
6( . <  ! < 
"+   !!   
< + & ! !" 
!&!!A&+
<  ! !& 2375.
7()!
"+&<
 +  <  <"
   "  
!&+A(
 +   "!! 
!!&+!

)<+  &(
 !! !  +   +
$ <& !  
  C  8   8=
+!&!
G&4>"."!
 !! 2"< 5 + 3> < (
<<! A 2"< '5  "(
  < "   
("!!&
 (A< ""  ! 
!"     + ."! 
  !" !  ! 
 & +!!
)   <
<+-"+=>(64 
"! 4"!"+
61(7= +: +  !&" < + (
!  !+" (
+=4>>(7>>>""
    &"  (

 << "  &< (
!& (A  !
!" ! <<  (
 ( A  !" 
 !! !  <  
 "  !& 2( A (
!"!&
<   <  ""   A(
!<   5  < (
"  !"  !
+!! !  < <(
   + ! ! 
+ "< 9& < + !!
63 !   < "<  
<  63 !   +
"<   "    " 
! !  ! !&
4> "  ."!   !! +
"&   < "<  3> <
A    + "< 
   ! & + ! 
< !"  ++""
   <" ! !
 3>> "  3>>> "  
&< <!  < !&
9 "  &+"  
+  !& +  B<!
 3 ! ! '! <  <!
+!<"346>748>3=>
31><!&
      ""
+&+  &
&+  !<" ! (
   !   
&< !& + !!  ) (
&"!
     "
 ! + ! ( 
 + ! <"  ( B<
   + ! +
 <    <<! &
!<"2&335
66


) <!     
  "<  A "< +
  !<" " '$ <
!!<
)!!+"+!
 + "<- "  !&
 <   &! +
&<   !&  <<
 < ! + A(
< A(
&! + " A < 
!&!A+""!
     < "" 
<:" !   !"  <:"
)!3+!!&
<<+"<
"<! <<!&
!&"!"   
&(   "(
  A  <! !(
! !&   + 
+  !"  !&  
A "< 2D>>305 2H"
35
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!!!&+"<
)!3-."!&<+"<
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$<!<25
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)"3=<25
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67
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   <  !& 
!"    " (
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< D>6=05  <    
 "< + !+    
<)&"  ! !"
<" 6 <  !&   +
"< + "  2D>>=5
+!+   "<
A"<238=4!I==>@
!5 H" =  6   !"
      < 
!!6<!&
H"=-,!"&"6<
!&+"<
H"6-HB<<<
!"6<!&+
<"<
&
)     "
 !&  + (
  A  < !"
  " A+
H"=  &"   !"  
 <  ! &"  ! !(
"<"6<!&
!+"<
A"<A
    "  !  (
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  • Background Long-term delivery is an important significant issue which is associated with mortality and fetal and maternal disorders. Based on the previous studies, consumption of dates affects uterine contractions and duration of delivery processes. This study aimed to study the effect of date consumption in late pregnancy on the duration of delivery processes in nulliparous women in 2013. Materials and Methods This randomized clinical trial was conducted among 182 nulliparous women 18–35 years who presented to OmAlBanin Hospital in Mashhad in 2013. The comparison has been made between 91 pregnant women who consumed 70–76 g dates daily from the 37th week of pregnancy and 91 pregnant women who did not consume dates. Data collection tool was a questionnaire and a checklist of daily dates’ intake. Data were analyzed using the Statistical Package for the Social Sciences software and statistical tests – chi-square and Mann–Whitney test, and P value <0.05 was considered significant. Results The average length of active phase (P = 0.0001), length of second phase (P = 0.0001), and third phase (P = 0.004) in two groups had statistically significant difference. The average length of the second phase (P = 0.03) and the third phase (P = 0.02) in case of spontaneous start of delivery in the intervention group was significantly lower than the control group. Use of oxytocin to accelerate delivery had a significant difference between the two groups (P < 0.001). Conclusion According to the results of this study, consuming dates in late pregnancy was effective in decreasing length of labor processes and reduced the need of oxytocin for labor acceleration. Thus, it is recommended to consume dates in women without contraindications.
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    Objectives: The date fruit has been shown to possess several health benefits. This study aims to determine the effects of date fruit consumption on the onset and progression of labour. Methods: A randomised controlled clinical study was conducted on 89 participants to assess the effects of date fruit consumption on the onset and progression of labour. Twenty-six participants consumed date fruits alone, and 32 consumed date fruits followed by drinking of water. Thirty-one served as controls. Results: There was a significant positive impact of consuming (rutab) date fruits on maternal outcomes in both the first and third stages of labour (p < 0.05 and p < 0.001, respectively). In addition, there was a significant relationship with the foetal well-being factors, such as healthy liquor, foetal heart rate, presence of caput, and Appearance, Pulse, Grimace, Activity, and Respiration (APGAR) score at 5 min (p < 0.05). The other maternal and foetal well-being factors showed no significant relationship with consumption of date fruits during labour. Conclusion: The present study showed a promising effect of (rutab) date fruit consumption on the duration of the stages of labour. No significant differences were observed between the date fruit consumers and their counterparts regarding cervical dilatation; rupture of membranes; strength, frequency, and regularity of uterine contractions; tocometric reports; and maternal progression factors. Additionally, the APGAR score at 5 min was better among the infants whose mothers consumed date fruits.
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    Objectives: Postpartum hemorrhage (PPH) is one of three main causes of maternal mortality and a life-threatening condition throughout the world. PPH can have irreversible complications for the mother even if it does not lead to death. This study was conducted to determine the effect of hydroalcoholic extract of Capsella bursa pastoris on early PPH. Design: The present study was a single-blinded, randomized, clinical trial. Setting: The study was conducted in Afzalipour Hospital of Kerman in 2015. Subjects: The subjects included 100 women who had given vaginal birth and met the study inclusion criteria. Intervention: The participants were selected and randomly assigned into an intervention group (n = 50) and a placebo group (n = 50). Immediately after placental expulsion, the intervention group was given 10 sublingual drops of the hydroalcoholic extract of Capsella bursa pastoris plus an infusion of 20 U of oxytocin in 1 L of Ringer's solution, and the control group was given 10 sublingual drops of the placebo plus an infusion of 20 U of oxytocin in 1 L of Ringer's solution. Outcome measures: The amount of bleeding was assessed in both groups. Hemoglobin and hematocrit levels were measured in all the participants 6 h after childbirth. The statistical analysis of the data was performed in SPSS-17 using the following tests: independent t, paired t, repeated measures ANOVA, Friedman's, Wilcoxon, Mann-Whitney, Fisher's exact, and chi square. P-value <0.05 was considered statistically significant. Results: There were no significant differences between groups in baseline characteristics (p > 0.05). After the intervention, there was significant decrease in the amount of postpartum bleeding in both groups. However, the mean decrease in the amount of bleeding was significantly more in the Capsella bursa pastoris group (p < 0.001). Conclusion: Compared with the mere administration of oxytocin, sublingual Capsella bursa drops appear to be effective in reducing PPH in this study. Further research regarding the efficacy and safety of various doses of Capsella bursa pastoris is required.
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