5-Fluorouracil-induced coronary vasospasm

Department of Cardiology, University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA.
Journal of Cardiovascular Medicine (Impact Factor: 1.51). 07/2009; 11(4):281-4. DOI: 10.2459/JCM.0b013e32832e934b
Source: PubMed


Cardiotoxicity due to 5-fluorouracil involves rare and life-threatening cardiotoxic events occurring in less than 1% of the patients. We describe a case of coronary vasospasm due to parenteral 5-fluorouracil, which did not recur with oral capecitabine. We also give a brief review of the cardiotoxicity of 5-fluorouracil, its treatment and prevention.

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