Background: Psoriasis is a common skin disorder affecting 1% to 3% of the population all over the world. Many etiological factors have been implicated but trace elements, especially zinc, may play an important role. Aims: This study was done to evaluate the serum level of zinc in patients with psoriasis and it's relation to clinical types, duration and surface area of the disease. Patients and
... [Show full abstract] Methods: Fifty patients (25 males & 25 females) with different ages and different types of psoriasis were chosen for this study. Also 50 non-psoriatic volunteers, sex and age matched were served as controls, evaluated for serum zinc level. Results: The result of this study has shown that 49 (98%) of psoriatic patients have low serum zinc compared with 2 (4 %) among controls (P=0.0001). The type of psoriasis may have an effect on serum zinc, the lowest mean serum zinc is found in palmo-planter (plaque) psoriasis (14% of patients) (P=0.025). Conclusions: From this study we can conclude that zinc deficiency may play a role in psoriasis since most patients (98%) have low serum level.