Dengue is a terrible viral fever caused by dengue virus belongs to Flaviviridae family. DV-1, DV-2, DV-3 and DV-4 are the four different serotypes in dengue virus. Mostly, it is spread by Aedes mosquitoes. Symptom includes asymptomatic fever, joint pain, muscle pain, hemorrhagic fever, and circulatory shock syndrome. In extremes, it causes death. Nowadays, it becomes a major health issue in the
... [Show full abstract] tropical and subtropical areas. From ancient times, in India, many herbal plants are used for herbal formulation. Carica papaya is a well-studied plant for its medicinal properties. Papain, chymopapain, lycopene, carotenoids, alkaloids, monoterpenoids, flavonoids (quercetin), mineral and vitamins are some of the biological active compounds present in its leaves, seeds, latex, ripe and unripe fruits. Clinical trials showed increase in platelet count when leaf extract of Carica papaya was orally administrated to dengue virus infected patients. Other plant parts also showed increased production of cytokines and larvicidal activity. This article provides a detailed view on usage of the Carica papaya plant parts to treat and control dengue virus infection.