Polyneuropathy and Cerebral Infarction Complicating Scrub Typhus

Department of Neurology, Kyung Hee University College of Medicine, Seoul, Korea.
Journal of Clinical Neurology (Impact Factor: 1.7). 04/2008; 4(1):36-9. DOI: 10.3988/jcn.2008.4.1.36
Source: PubMed


We describe a 64-year-old man with scrub typhus who presented with both polyneuropathy and cerebral infarction. A eurological examination revealed a confused mental state, stiff neck, hearing impairment, symmetric weakness, sensory loss, and ataxia. Electrophysiologic studies showed demyelinating sensorimotor polyneuropathy and sensorineural hearing loss. Brain magnetic resonance imaging showed multiple infarctions. Brain involvement or polyneuropathy associated with scrub typhus has been rarely reported, and the pathogenic mechanism underlying the multiple neurological complications remains to be elucidated.

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Available from: Sung-Sang Yoon, Jun 03, 2014
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    • "The involved cranial nerves are the optic [17], abducens, facial and cochlear [35] nerves. Peripheral nervous system involvement reported are mononeuritis multiplex [36], brachial plexus neuropathy [37], polyneuropathy [28], myelitis [30], [38] and Guillain-Barre syndrome (GBS) [25]. "
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