X-ray phase-contrast microscopy and microtomography

Optics Express (Impact Factor: 3.49). 10/2003; 11(19):2289-302. DOI: 10.1364/OE.11.002289
Source: PubMed


In-line phase contrast enables weakly absorbing specimens to be imaged successfully with x-rays, and greatly enhances the visibility of fine scale structure in more strongly absorbing specimens. This type of phase contrast requires a spatially coherent beam, a condition that can be met by a microfocus x-ray source. We have developed an x-ray microscope, based on such a source, which is capable of high resolution phase-contrast imaging and tomography. Phase retrieval enables quantitative information to be recovered from phase-contrast microscope images of homogeneous samples of known composition and density, and improves the quality of tomographic reconstructions.

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Available from: Sheridan Clare Mayo, Aug 18, 2014
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