Primary anorectal melanoma is rare, accounting for 0.5% of all colorectal and anal malignancies and only 0.4-1.6% of all melanomas. Metastatic disease is present in 15-38% of patients at the time of presentation. Reported sites of metastases from anorectal malignant melanoma are pelvis, rectum, liver, vagina, lung, bone, skin, brain, colon, perineum, groin and the breast.
We present a unique ... [Show full abstract] case and review the current literature. A fifty-eight year old lady underwent an abdomino-perineal resection for primary melanoma of the anal canal. Two months post-operatively she complained of visual disturbances. Fundoscopy demonstrated multiple metastases in the posterior poles of both eyes. Complete resolution was achieved with ocular radiotherapy.
After an extensive literature search, to our knowledge, we believe this is the first report of metastases to the eye from a primary anal melanoma.