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Analysis on the Natural Remedies to Cure Dandruff/Skin Disease-causing Fungus - Malassezia furfur.

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A comparative study was conducted on the levels of effectiveness, of natural remedies such as cow's urine, lemon, boiled rice water, Neem extract etc. in curing dandruff and inhibiting the growth of the causative fungus Malassezia. Various plating techniques were applied using modified Oil - Potato Dextrose Agar as the nutrient medium for the fungal growth. Cow's urine was found to be more stable and effective in inhibiting the fungus, along with boiled rice-water. Lemon juice was highly effective though over a shorter period.
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... This disease is of global prevalence and needs effective therapeutic remedy. There are natural effective remedies to control dandruff in Ayurveda [5] but presently people are depending on commercial shampoos containing some antifungal compounds like miconazole, ketoconazole, selenium sulphide etc. Plant products contain various compounds like alkaloids, flavanoids, tannins, terpenoids etc which have efficient antifungal activity [6] [7] . These compounds can be used in combination as polyherbal mixtures for controlling dandruff. ...
... These were used for antifungal assays. (Table 2) along with their generic names, appropriate plant part used and dosage [7] . The plant part was collected from the plant source washed thoroughly, cut into smaller pieces and ground into fine paste. ...
... The fine paste was made into a solution with sterile distilled water, centrifuged at 5000 rpm and the supernatant was used as sample for anti fungal assays. Table 2: Different plant extracts used and their common names [7] Scientific name Plant part used for extraction of active compound Antifungal Assays: The antifungal activity of antifungal shampoos and plant extracts was tested by disc diffusion method and agar well assay [13] . ...
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Context: Dandruff a very common scalp disorder with high prevalence in population is caused by numerous host factors in conjunction with Malassezia furfur. Most of the commercially available anti-dandruff hair shampoos contain some form of antifungal agent(s) that appear to reduce the incidence of the disease. There are no good scientific studies done to prove the antifungal activity of commercially available hair shampoos. Aim: In this study commercially available shampoos were assessed for antifungal activity against a human dandruff isolate of M. furfur. The shampoos were Head & Shoulders, Clinic All Clear, and Pantene etc. The results demonstrated that all six of the assayed hair shampoos have some antifungal effect on growth of M. furfur. These products have poor efficacies, more side effects and give scope for recurrence of symptoms. Methods and Materials: Therefore different plant extracts that possess various active compounds which have antifungal activity could help to overcome the incidence of the disease and also avoid the emergence of resistance in the pathogen. The plant extracts were tested in different concentrations like 1:5, 1:10, 1:20 and they were hibiscus, neem, soap nut, etc. The inhibitory action was studied using agar well assay and disc diffusion method and the results indicated in percentage of inhibition. Conclusion: The study was significant as not only efficient known plant products with anti-dandruff activity could be compared with commercially available shampoos but also their better efficacies at minimum concentrations could be identified. This can help make a polyherbal mixture that could be incorporated in hair oil or shampoos for better anti-dandruff activity.
... Cow urine use in Kaphodar(~one of type of Ascites) 21 Rohitakadi yoga in Udara(~Ascites)roga 22 ...
... Also CU shows significant effect in various microorganisms which is responsible different diseases in crops. Study found that Lemon Juice extract and Neem leaves extract less effective than CU 21 . CUC (cow urine concoction) 5% showed maximum antifungal activity against A. niger (93%), A. oryzae (92.67%) and A. flavus(83%). ...
... Antimicrobial activities of cow productsUrine of indigenous Geer cow showed superior antifungal activity as compared to standard antibiotic Amphoterecin B (50µg), thus suggesting cow urine as a natural antifungal agent(Rana and De, 2013). Beneficial effects of cow urine were also suggested against Malassezia fungus, a fungus which is responsible for dandruff(Sathasivam et al., 2010, Kumar, 2013& Hoh et al., 2017. Additionally, studies demonstrating cow urine benefits against plant pathogenic fungi are also available.Jandaik et al (2015) investigated the effects of different concentrations of urine against three different fungi (Rhizoctonia solani, Fusarium oxysporum, and Sclerotium rolfsii) of okra and fenugreek vegetables and found out that incidence of fungal attack has been reduced with increasing concentration of cow urine. ...
... Cow urine was found to be more effective than neem leaves extract and lemon juice extract. It is highly stable and capable of inhibiting the growth of Malassezia fungi (90-95%) than rice water (due to B. cereus growth in rice water) which was stably capable of inhibiting 85-90% of the growth for 3-4 days [43] . An in-vitro study revealed that urine of outdoor grazing cow possesses more antifungal effect than indoor feeding cow. ...
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Cow is worshiped as "mother of mankind". It is very respective animal in Hinduism. Cow urine and cow dung are described as important excretions of animal origin. Cow urine contains many active compounds like phenols, amino acids, volatile and non-volatile substances which show marvelous antimicrobial activities. Ayurveda also described the traditional use of cow urine in cure of many harmful diseases.
... CU inhibits 90-95% growth of the Malassezia fungi, which is responsible for causing dandruff. [4,34,35] The urine collected from outdoor feeding cow (OCU) has more effective to inhibit the growth of fungi in an in vitro experiment compared to indoor feeding CU (ICU). It was observed that 10% OCU has completely inhibited the growth of Penicillium notatum, Trichoderma viride, and Alternaria solani as compared to 20% ICU. ...
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In spite of the progresses in science and technology, India is well-known for its traditional system of medicine. Traditional use of medicine is practiced since the era of vedic. The Indian traditional system of medicine such as Ayurveda, Siddha, and Unani has a very rich history of their effectiveness. As India is a rich repository of herbal and medicinal plants, these traditional systems of medicine use herbal plants and minerals as the vital source for drugs. Along with the use of herbal plants, the Indian traditional system of medicine, especially Ayurvedic system, uses animal urine as a source of drug. In Ayurveda, the properties of the urine of eight different animals along with the human urine and also its uses are described. Basically, cow's urine (CU) is used mainly for the treatment of various diseases in Ayurveda. Apart from CU, urine of the other animals such as goat, sheep, buffalo, elephant, horse, camel, and donkey were also used as remedies for the treatment of different diseases. An attempt has been made in this article to bring forth the traditional and therapeutic use of cow and goat urine (GU) and also highlights its efficacy. This article will provide brief information on cow and GU and their application in traditional practice of medicine which may help people working in this area.
... Neem, or Azadirachta indica, is well known for its numerous pharmacological properties including antibacterial, antifungal, antiulcer, repellent and pesticide among others. 22 These activities arise due to the presence of nimbin (C30H36O9), nimbinene desacetylnimbinase, nimbandial, nimbolide (C27H30O7) and quercentin (C15H10O7) in neem leaves. 23,24,25 Hence, not surprisingly, neem leaf extracts have been used to control leprosy, intestinal helminthiasis and respiratory disorders in children 26 26 Thus it would be interesting to study the antimicrobial effect of neem against the selected pathogens too, adding to the repertoire of microbial species that are susceptible to inhibition by neem. ...
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There is a growing demand today for naturally derived drugs and medicine in place of synthetic drugs that are more commercially available. Such drugs derived from indigenous plants are effective as they contain potent therapeutically active compounds of the plants that show antimicrobial activity against a variety of pathogens that cause common diseases. Such diseases as periodontitis and oral candidiasis are a growing concern these days. This study was undertaken to investigate the antimicrobial activity of two indigenous Indian plants, Azadirachta indica and Murraya koenigii and their synergistic effect, if any, against three pathogenic microorganisms associated with oral diseases and one pathogenic bacteria known to be a nosocomial causative agent. Three bacterial species (Streptococcus mutans, Streptococcus gordonii, Pseudomonas aeruginosa) and one fungal species (Candida albicans) were selected for antimicrobial assays. Both ethanolic and methanolic extracts were prepared from the leaves of the two plant species in addition to an aqueous extract of A. indica and an n-hexane extract of M. koenigii. Antibacterial and antifungal assay was done using agar well diffusion method under standard culture conditions. Inhibitory activity was observed for all extracts against P. aeruginosa while A. indica and M. koenigii showed ineffectiveness in inhibiting growth of C. albicans and S. mutans respectively. C. albicans and S. mutans were selected for study of synergistic effect based on the results of the initial assay, however there was no synergistic activity observed for any combination of extract mixtures.
... CU was highly stable and capable in inhibiting the growth of Malassezia fungi (90-95%) responsible for causing dandruff for a longer time (4-5 days), than rice water (due to B. cereus growth in rice water) which was stably capable of inhibiting 85-90% of the growth for 3-4 days. Neem leaves extract and Lemon Juice extract were comparatively less effective in this study [40]. ...
... CU was highly stable and capable in inhibiting the growth of Malassezia fungi (90-95%) responsible for causing dandruff for a longer time (4-5 days), than rice water (due to B. cereus growth in rice water) which was stably capable of inhibiting 85-90% of the growth for 3-4 days. Neem leaves extract and Lemon Juice extract were comparatively less effective in this study [40]. ...
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In the grim scenario where presently about 70% of pathogenic bacteria are resistant to at least one of the drugs for the treatment, cue is to be taken from traditional/indigenous medicine to tackle it urgently. The Indian traditional knowledge emanates from ayurveda, where Bos indicus is placed at a high pedestal for numerous uses of its various products. Urine is one of the products of a cow with many benefits and without toxicity. Various studies have found good antimicrobial activity of cow’s urine (CU) comparable with standard drugs such as ofloxacin, cefpodoxime, and gentamycin, against a vast number of pathogenic bacteria, more so against Gram-positive than negative bacteria. Interestingly antimicrobial activity has also been found against some resistant strains such as multidrug-resistant (MDR) Escherichia coli and Klebsiella pneumoniae. Antimicrobial action is enhanced still further by it being an immune-enhancer and bioenhancer of some antibiotic drugs. Antifungal activity was comparable to amphotericin B. CU also has anthelmintic and antineoplastic action. CU has, in addition, antioxidant properties, and it can prevent the damage to DNA caused by the environmental stress. In the management of infectious diseases, CU can be used alone or as an adjunctive to prevent the development of resistance and enhance the effect of standard antibiotics.
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