Article

Cost-Effectiveness of Tdap Vaccination of Adults Aged >= 65 Years in the Prevention of Pertussis in the US: A Dynamic Model of Disease Transmission

Old Dominion University, United States of America
PLoS ONE (Impact Factor: 3.23). 01/2014; 9(1):e72723. DOI: 10.1371/journal.pone.0072723
Source: PubMed

ABSTRACT

In February 2012, the Advisory Committee on Immunization Practices (ACIP) advised that all adults aged ≥65 years receive a single dose of reduced-antigen-content tetanus, diphtheria, and acellular pertussis (Tdap), expanding on a 2010 recommendation for adults >65 that was limited to those with close contact with infants. We evaluated clinical and economic outcomes of adding Tdap booster of adults aged ≥65 to “baseline” practice [full-strength DTaP administered from 2 months to 4–6 years, and one dose of Tdap at 11–64 years replacing decennial Td booster], using a dynamic model.

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Available from: L.J. Mcgarry, Feb 03, 2015
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