Cognitive impairment, in past decades, has been consistently reported in patients with schizophrenia [1]. Neurocognitive disability appears early in the course of the disease, even in prodromal phases, and these deficits are widely present in different stages of the illness whether in patients or in their first-degree family members [2]. In 2004, the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) project has identified seven distinct cognitive domains that are impaired in patients with schizophrenia: speed of processing, attention/vigilance, working memory, verbal and visual learning, reasoning and problem solving, and social cognition [3–5]. Moreover, in the third meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) project, it was cleared that six areas of cognitive domains are damaged in patients with schizophrenia: perception, working memory, attention, executive functions, long-term memory, and social cognition [6]. Regarding social cognitive deficits, they include impairments in facial affect recognition, in perceiving and interpreting social cues, in theory of mind (ToM), and in the ability to make appropriate causal attributions for events [7]. Several studies have shown that both neurocognitive and social cognitive deficits are among the major causes of severe functional disabilities in patients with schizophrenia and they are also related to a worse outcome of the disorder [8–10]. In a comprehensive literature review, Green et al. [10] underlined that different cognitive deficits might have an impact on specific areas of psychosocial functioning. As a matter of fact, cognitive deficits seem to explain 20–60% of the variance of everyday functioning [3, 4, 11]. The influence of cognition on functional outcomes may happen through its influence on functional capacity, the ability to perform critical everyday living skills [12]. Thus, functional capacity may actually be considered as a proxy measure between neurocognition and everyday functioning and it has been found to be quite strongly associated with cognitive performance [13]. Recent studies have shown how cognitive impairment predicts functional outcomes even more than positive and negative symptoms and how it is associated with disability in phases of clinical remission too [2, 14]. From the greater and detailed knowledge of the role and meaning of cognitive impairment in schizophrenia, its improvement became an essential target in the treatment and in the clinical management of the illness [15]. In order to restore cognitive deficits in schizophrenic patients, there are different pharmacological and non-pharmacological approaches developed. Whereas pharmacological interventions include approved treatments (e.g., antipsychotics and antidepressants) and under-study treatments, non-pharmacological interventions include cognitive remediation, noninvasive brain stimulation techniques, and physical activity techniques [16–20].