The Ketogenic Diet for the Treatment of Pediatric Status Epilepticus

Department of Pediatrics, Section of Epilepsy, Lurie Children's Hospital, Chicago, Illinois. Electronic address: .
Pediatric Neurology (Impact Factor: 1.7). 11/2013; 50(1). DOI: 10.1016/j.pediatrneurol.2013.07.020
Source: PubMed


Refractory status epilepticus carries a high risk of morbidity and mortality for children. Traditional treatment of status epilepticus consists of multiple anticonvulsant drugs and, if needed, induction of a medical coma. The ketogenic diet has been used for intractable epilepsy for many years. The purpose of this article is to report a case series of five patients with refractory status epilepticus successfully managed with the ketogenic diet.
A summary of pediatric patients with refractory status epilepticus treated with diet was performed.
Ketogenic diet therapy should be considered as a treatment option in pediatric patients with refractory status epilepticus.

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Available from: Beth Zupec-Kania, Apr 02, 2014
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Questions & Answers about this publication

  • David Camacho-Valadez added an answer in Internet Search:
    What is the Root Cause of Epilepsy?

    From Internet search Epilepsy is “a neurological disorder marked by sudden recurrent episodes of sensory disturbance, loss of consciousness, or convulsions, associated with abnormal electrical activity in the brain”.

    What is the root cause that trigger Epilepsy?

    Are the root cause the same for children and adult?

    Which is the best treatment for Epilepsy?

    Can we prevent Epilepsy from relapse for a person who is suffering from Epilepsy? or medical treatment is the only way?

    Can Epilepsy disappears or goes away by itself after a while or will it lasts for the whole life?  If yes how long?

    Is there any negative impact on a child e.g. confidence level, introvertedness,  slow in learning, reduction in IQ & EQ etc when s/he realized s/he has contracted with Epilepsy i.e. happen for many times / episodes of fits?

    Feel free to share your professional comments / advice.  Thanks.

    David Camacho-Valadez

    Hello, take a look at this current articles (perhaps you've already read).

    The first one for adults, the another two are in children population. 

    I hope can be useful to you.

    Kaski, D., & Cockerell, C. (2015). Advances in the diagnosis and management of epilepsy in adults. Prescriber, 26(3), 12-19.

    O'Connor, S. E., Richardson, C., Trescher, W. H., Byler, D. L., Sather, J. D., Michael, E. H., ... & Zupec-Kania, B. (2014). The ketogenic diet for the treatment of pediatric status epilepticus. Pediatric neurology, 50(1), 101-103.

    Meeraus, W. H., Petersen, I., & Gilbert, R. (2015). Association between antibiotic prescribing in pregnancy and cerebral palsy or epilepsy in children born at term: a cohort study using the health improvement network. PloS one, 10(3), e0122034.

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