A product of science, religion, and national culture, cosmism is reflected in academic and popular views about our place in the universe, space exploration, and human destiny. Although linked historically to the Russians, cosmism captures many aspects of American thinking about space. The present comparison shows that prophets, prophecies, striving for perfection, utopian visions, and hopes for salvation are evident in both Russian and American thought, but that there are also differences. Geert Hofstede's cross-cultural research on national values-power distance, individualism, masculinity, and uncertainty avoidance-is useful for understanding Russian-American differences. Russian acceptance of power inequalities, collectivism, concern for group welfare, and aversion to uncertainty lead to constellations of beliefs and emotions about spaceflight that differ from those bred by American egalitarianism, individualism, obsession with personal achievement, and acceptance of uncertainty. Both Russian and American thinking include occult and paranormal phenomena, but Americans have been more reluctant to assimilate such influences within mainstream science. As a concept, American cosmism captures the occasional blurring of the lines between religion and science in discussions of humanity's place in the universe and future in space.