Excised larynx evaluation of wedge-shaped adjustable balloon implant for minimally invasive type I thyroplasty

ArticleinThe Laryngoscope 124(4) · April 2014with8 Reads
Impact Factor: 2.14 · DOI: 10.1002/lary.24409 · Source: PubMed
Abstract

To describe the method of inserting a wedge-shaped adjustable balloon implant (wABI) via a minithyrotomy for medialization thyroplasty and evaluate its effect on a range of phonatory parameters using the excised larynx bench apparatus. Repeated measures with each larynx serving as its own control. A prototype wABI was deployed in six excised canine larynges of various sizes through a minithyrotomy and then filled with saline. Mucosal wave, aerodynamic, and acoustic parameters were measured for three conditions: normal, vocal fold paralysis, and paralysis with the wABI. Phonation threshold pressure (P < .001), flow (P < .001), and power (P = .002) were significantly lower for wABI compared to paralysis trials; values did not differ significantly from normal trials. Percent jitter (P = .002) and percent shimmer (P = .007) were also significantly decreased compared to the paralysis condition, and values were not significantly different compared to normal. The mucosal wave was preserved after insertion of the wABI. Effective vocal fold medialization with preservation of the mucosal wave was observed with the wABI in this preliminary excised larynx experiment. The wABI offers the potential for a minimally invasive insertion in addition to postoperative adjustability. Further studies in living animals and humans are warranted to evaluate clinical utility. LEVEL OF EVIDENCE: NA.

    • "This is commonly done with perichondrium , suture, or strap muscle. Finally, recent studies from Hoffman et al. [81, 82] have reported on a synthetic freeform wedge-shaped adjustable balloon that can be placed in the paraglottic space and sized appropriately by inflating with saline solution. Other preformed implants that are variably customizable are shown inTable 1. "
    [Show abstract] [Hide abstract] ABSTRACT: Laryngeal framework surgery is the current gold standard treatment for unilateral vocal fold paralysis. It provides a permanent solution to glottic insufficiency caused by injury to the recurrent laryngeal nerve. Various modifications to the original Isshiki type I laryngoplasty procedure have been described to improve voice and swallowing outcomes. The success of this procedure is highly dependent on the experience of the surgeon as it epitomizes the intersection of art and science in the field. The following article reviews the evidence, controversies, and complications related to laryngoplasty for unilateral vocal fold paralysis. It also provides a detailed analysis of how and when arytenoid-positioning procedures should be considered, and summarizes the literature on postoperative outcomes.
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