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This paper investigates the combination of multiresolution methods for feature extraction for lung cancer. The focus is on the impact of combining wavelet and curvelet on the accuracy of the disease diagnosis. The paper investigates feature extraction with two different levels of wavelet, two different wavelet functions and the combination of wavelet and curvelet to obtain a high classification rate. The findings suggest the potential of combining different multiresolution methods in achieving high accuracy rates.

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... Cluster-K-Nearest Neighbor (C-K-NN) [13], [14] is a classifier that combines two algorithms; the K-means modified algorithm [15] and the K-Nearest neighbor. Data is clustered into classes and sub-classes with a centre point to represent each class using K-means. ...
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A neural network ensemble (NNE) scheme was designed for distinguishing probably benign, uncertain and probably malignant lung nodules on thin-section CT images. To construct the NNE scheme, a multilayer neural network with the back-propagation algorithm (BPNN), a radial basis probabilistic neural network (RBPNN) and a learning vector quantization neural network (LVQNN) were employed, and the Bayesian criterion was used as combination rule to integrate the outputs of individual neural networks. Experimental results illustrated that the proposed classification scheme had higher classification accuracy (78.7%) as compared to the best individual classifier (LVQNN: 68.1%), as well as to another NNE scheme with the same individual neural networks but with majority voting combination rule.
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An automated lung nodule detection system can help spot lung abnormalities in CT lung images. Lung nodule detection can be achieved using template-based, segmentation-based, and classification-based methods. The existing systems that include a classification component in their structures have demonstrated better performances than their counterparts. Ensemble learners combine decisions of multiple classifiers to form an integrated output. To improve the performance of automated lung nodule detection, an ensemble classification aided by clustering (CAC) method is proposed. The method takes advantage of the random forest algorithm and offers a structure for a hybrid random forest based lung nodule classification aided by clustering. Several experiments are carried out involving the proposed method as well as two other existing methods. The parameters of the classifiers are varied to identify the best performing classifiers. The experiments are conducted using lung scans of 32 patients including 5721 images within which nodule locations are marked by expert radiologists. Overall, the best sensitivity of 98.33% and specificity of 97.11% have been recorded for proposed system. Also, a high receiver operating characteristic (ROC) A(z) of 0.9786 has been achieved.
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Lung cancer is a disease with significant prevalence in several countries around the world. Its difficult treatment and rapid progression make the mortality rates among people affected by this illness to be very high. Aiming to offer a computational alternative for helping in detection of nodules, serving as a second opinion to the specialists, this work proposes a totally automatic methodology based on successive detection refining stages. The automated lung nodules detection scheme consists of six stages: thorax extraction, lung extraction, lung reconstruction, structures extraction, tubular structures elimination, and false positive reduction. In the thorax extraction stage all the artifacts external to the patient's body are discarded. Lung extraction stage is responsible for the identification of the lung parenchyma. The objective of the lung reconstruction stage is to prevent incorrect elimination of portions belonging to the parenchyma. Structures extraction stage comprises the selection of dense structures from inside the lung parenchyma. The next stage, tubular structures elimination eliminates a great part of the pulmonary trees. Finally, the false positive stage selects only structures with great probability to be nodule. Each of the several stages has very specific objectives in detection of particular cases of lung nodules, ensuring good matching rates even in difficult detection situations. We use 33 exams with diversified diagnosis and slices numbers for validating the methodology. We obtained a false positive per exam rate of 0.42 and false negative rate of 0.15. The total classification sensitivity obtained, measured out of the nodule candidates, was 84.84%. The specificity achieved was 96.15% and the total accuracy of the method was 95.21%.
Methodology for automatic detection of lung nodules in computerized tomography images
  • J R F Da Silva
  • Sousa
J. R. F. da Silva Sousa, et al., "Methodology for automatic detection of lung nodules in computerized tomography images," Computer Methods and Programs in Biomedicine, vol. 98, pp. 1-14, 2010.
Robust and Automated Lung Nodule Diagnosis from CT Images Based on Fuzzy Systems
  • S A Kumar
S. A. Kumar, et al., "Robust and Automated Lung Nodule Diagnosis from CT Images Based on Fuzzy Systems," in Process Automation, Control and Computing (PACC), 2011 International Conference on, 2011, pp. 1-6.
Modified k-means cluster
  • B B Samir
B. B. Samir, "Modified k-means cluster," Universiti Teknologi PETRONAS2008.