Article

Starvation favors glioma stem cells

Department of Pediatrics, University of California, San Francisco, San Francisco, California, United States
Nature Neuroscience (Impact Factor: 16.1). 10/2013; 16(10):1359-61. DOI: 10.1038/nn.3524
Source: PubMed

ABSTRACT

High-grade glioblastomas survive glucose-poor environments by becoming more stem cell–like. Increased glucose uptake by the transporter Glut3, a new biomarker of poor clinical outcome, drives this enhanced malignant progression.

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