Musical hallucinations after pontine ischemia: The auditory Charles Bonnet syndrome?

Department of Psychiatry and Psychotherapy, Charitéplatz 1, 10117, Berlin, Germany.
Journal of Neurology (Impact Factor: 3.38). 09/2013; 260(10). DOI: 10.1007/s00415-013-7114-9
Source: PubMed
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    • "n , 2010 ; Padala et al . , 2010 ; Shoyama et al . , 2010 ; Wong and Bhalerao , 2010 ; Bleich - Cohen et al . , 2011 ; Huntley et al . , 2011 ; Bhatt and de Carpentier , 2012 ; Calabrò et al . , 2012 ; Johns and Zuromskis , 2012 ; Ozsarac et al . , 2012 ; Serrador - García et al . , 2012 ; Simões et al . , 2012 ; Teunisse and Olde Rikkert , 2012 ; Dinges et al . , 2013 ; Giermanski et al . , 2013 ; Vitorovic and Biller , 2013 ; Abdel - Aziz and Pomeroy , 2014 ; Aizawa et al . , 2014 ; Bergman et al . , 2014 ; Colon - Rivera and Oldham , 2014 ; Futamura et al . , 2014 ; Husain et al . , 2014 ; Islam et al . , 2014 ; Kataoka and Ueno , 2014 ; Kumar et al . , 2014 ; Mansoor and Ganzini , 2014 ; Woo et al"
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    ABSTRACT: Background: Despite an increased scientific interest in musical hallucinations over the past 25 years, treatment protocols are still lacking. This may well be due to the fact that musical hallucinations have multiple causes, and that published cases are relatively rare. Objective: To review the effects of published treatment methods for musical hallucinations. Methods: A literature search yielded 175 articles discussing a total number of 516 cases, of which 147 articles discussed treatment in 276 individuals. We analyzed the treatment results in relation to the etiological factor considered responsible for the mediation of the musical hallucinations, i.e., idiopathic/hypoacusis, psychiatric disorder, brain lesion, and other pathology, epilepsy or intoxication/pharmacology. Results: Musical hallucinations can disappear without intervention. When hallucinations are bearable, patients can be reassured without any other treatment. However, in other patients musical hallucinations are so disturbing that treatment is indicated. Distinct etiological groups appear to respond differently to treatment. In the hypoacusis group, treating the hearing impairment can yield significant improvement and coping strategies (e.g., more acoustic stimulation) are frequently helpful. Pharmacological treatment methods can also be successful, with antidepressants being possibly more helpful than antiepileptics (which are still better than antipsychotics). The limited use of acetylcholinesterase inhibitors has looked promising. Musical hallucinations occurring as part of a psychiatric disorder tend to respond well to psychopharmacological treatments targeting the underlying disorder. Musical hallucinations experienced in the context of brain injuries and epilepsy tend to respond well to antiepileptics, but their natural course is often benign, irrespective of any pharmacological treatment. When intoxication/pharmacology is the main etiological factor, it is important to stop or switch the causative substance or medication. Conclusion: Treatments for musical hallucinations tend to yield favorable results when they target the main etiological factor of these phenomena. There is a need to establish the natural course of musical hallucinations, their response to non-pharmacological treatments, and their effects on the patient's quality of life. There is also a need to standardize the assessment of treatment responses, and document long-term follow up.
    Full-text · Article · Jun 2015 · Frontiers in Psychology
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    ABSTRACT: Musical hallucinations are complex auditory perceptions in the absence of an external acoustic stimulus and are often consistent with previous listening experience. Their causation can be classified as associated with either psychiatric disorders, such as schizophrenia, or organic disorders, such as epilepsy or sensorineural deafness. Non-epileptic musical hallucinosis due to lesions of the central auditory pathway, especially of the thalamocortical auditory radiation, is rare. We describe the case of an 85-year old ethnic Chinese woman with a history of transient ischemic attacks and chronic bilateral hearing impairment, who experienced an acute onset of left unilateral musical hallucinations. Our patient did not experience any psychiatric symptoms and there was no other neurological deficit. Pure tone audiometry revealed bilateral hypacusis and magnetic resonance imaging revealed a right non-dominant hemisphere sublenticular lacunar infarct of the thalamocortical auditory radiation. Our patient was managed expectantly and after three months her symptoms subsided spontaneously. We propose that all patients with monoaural musical hallucinations have brain imaging to rule out a central organic cause, especially within the non-dominant hemisphere, regardless of the presence of a hearing impairment.
    Full-text · Article · Dec 2014 · Journal of Medical Case Reports