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Histological Evaluation of Peri-Implant Soft Tissues in Immediately Loaded Implants Featuring Different Implant-Abutment Connections: A Preliminary Study

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Abstract

The aim of the present study is to evaluate the pen-implant soft tissues and the amount of inflammatory cells around two different implant-abutment connections (self-locking conical connection with platform switching and screwed connection with standard abutment and internal anti-rotational system). Histological analysis was made of 14 implants, 7 with self-locking Morse tapered connection (experimental group A) and 7 with screw-retained anti-rotational connection (control group B). Sixty days after non-functional immediate loading, pen-implant tissue biopsies were performed. In the samples taken from the experimental group the pen-implant connective tissue consisted of a greater density of collagen and fibroblasts compared to the connective tissue of the control group. The experimental group specimens showed less inflammatory infiltrate close to the self-locking tapered connection compared to the tissues around the screw-retained connection. The SEM observations showed less microgap in the self-locking conical connection than in the screw connections with standard abutment and internal anti-rotational system. The presence of connective tissue with few inflammatory cells and the absence of inflammatory infiltrate, in self-locking conical connection implants is due to the minimal size of the implant-abutment microgap that does not allow the passage of fluids and bacteria from the oral cavity to the implant thus preventing tissue inflammation.
Wednesday, November 7, 2012
Wednesday, November 7, 2012
Wednesday, November 7, 2012
Wednesday, November 7, 2012
Wednesday, November 7, 2012
Wednesday, November 7, 2012
Wednesday, November 7, 2012
Wednesday, November 7, 2012
... Thus, to conclude the section, when compared between other internal abutment connections, Morse tapered connections distributed stress better (Merz et al., 2000;Pessoa et al., 2010;Schmitt et al., 2014) at the alveolar bone level and better resistance to bacterial leakage and its by-products (do Nascimento et al., 2012;Koutouzis et al., 2011). Morse taper connections with platform switching showed reduced inflammation (Guerra et al., 2012;Oskarsson et al., 2018;Macedo et al., 2016) and bone loss (Caricasulo et al., 2018;Romanos and Javed, 2014;Vairo and Sannino, 2013). Hence, Morse taper connection preserves the biological width better than other internal connections. ...
Chapter
The role of the biologic width of healthy tissues around dental implants is well evidenced. The interface between the implant biomaterials and hard and soft peri-implant tissues is vital in the overall clinical success of dental implants. Loss of peri-implant hard tissue has a direct effect on the gingival architecture, which can lead to suboptimal clinical outcome. In this chapter, the factors influencing peri-implant hard and soft tissue interfaces are thoroughly discussed. Currently available literature on implant materials, design, and surgical factors such as timing, loading protocols, and abutment connection has also been critically appraised.
... Thus, to conclude the section, when compared between other internal abutment connections, Morse tapered connections distributed stress better (Merz et al., 2000;Pessoa et al., 2010;Schmitt et al., 2014) at the alveolar bone level and better resistance to bacterial leakage and its by-products (do Nascimento et al., 2012;Koutouzis et al., 2011). Morse taper connections with platform switching showed reduced inflammation (Guerra et al., 2012;Oskarsson et al., 2018;Macedo et al., 2016) and bone loss (Caricasulo et al., 2018;Romanos and Javed, 2014;Vairo and Sannino, 2013). Hence, Morse taper connection preserves the biological width better than other internal connections. ...
Chapter
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... DISCUSSSION Non surgical periodontal therapy may be performed with various devices as hand instruments, mechanical (sonic and ultrasonic) instruments and laser therapy. In addition, antiseptics (15) may be useful in the treatment of periodontal and peri implant diseases in which many microbiota (16) determine an host response with the increasing expression of different inflammation mediators (17,18). Hand instrumentation allow good tactile sensation while minimizing the risk of contaminated aerosol production. ...
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... Severalstudies have indicatedpotential roles for dietary antioxidants in the reduction of degenerative diseases such as vascular dementia, cardiovascular disease, and cancer. Scientific investigation of the biochemistry of the structure and the mode of action of antioxidant vitamins have cleared up many ofthe puzzles regarding their medical relevancy to cancer.Antioxidants may in theory neutralize the reactive species that are produced by neutrophilic leukocytes during phagocytosis and as part of normal cellular respiration (48)(49)(50)(51)(52)(53). Antioxidants may modulate signal transduction and gene expression in immune cells. ...
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Cancer cells invade surrounding tissues and metastasize to distant sites. Diet high in fat is a strong link to, and perhaps causes, a high incidence of tumours. Trans-fatty acid might impair the function and it could be involved in the development of cancer. Cholesterol is also strongly suspected to be involved in the development of tumours, therefore it is important for everyone to eat well, especially for people with cancer to prevent the body tissues from breaking down and helping to rebuild the normal tissue that may have been affected by the treatments. Factors secreted by adipocytes and macrophages such as TNF-alpha and other inflammatory proteins are involved in inflammation in cancer. In addition, MCSF which up-regulates adipocyte tissue is also important for the stimulation of fat cell proliferation and is expressed by human adipocytes. Many cytokines, such as IL-1, IL-6, IL-8, IL-32, IL-33 and MCP-1, are biomarkers for cancer and chronic diseases along with transcription factors NFkB and AP-1; these last two factors are important bioactive substances on the molecular mechanism of the control of genes which in turn affect cellular metabolism. In this paper we revisit the interrelationship between cancer and metabolism.
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