No full-text available
To read the full-text of this research,
you can request a copy directly from the authors.
Asymmetric Synthesis of 2Aryl2,3-dihydro-4-quinolones by Rhodium-Catalyzed 1,4Addition of Arylzinc Reagents in the Presence of Chlorotrimethylsilane
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
ResearchGate has not been able to resolve any citations for this publication.
[reaction: see text] The first catalytic asymmetric synthesis of 2-aryl-2,3-dihydro-4-quinolones has been developed by way of a rhodium-catalyzed 1,4-addition of arylzinc reagents to 4-quinolones. These 1,4-adducts can be obtained with high enantioselectivity by the use of (R)-binap as a ligand, and high yields are realized by conducting the reactions in the presence of chlorotrimethylsilane.