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The laxative effect of fresh pulp aqueous extracts of Thai Tamarind cultivars
Abstract
Tamarindus indica Linn (Caesalpiniaceae), is widespread cultivated in Thailand. People consume it both raw and ripe as fresh fruit and favor its sour and sweet taste. The pulp, leaves, seeds and bark are used in traditional medicine for several applications e.g. anti-helminthic (seeds), treatment of constipation (ripened fruit) [1]. Fresh pulp aqueous extracts of five Thai tamarind cultivars (one sour tamarind: Preaw-yak, four sweet tamarinds: Sri chom poo, Kanti, Sri tong boa, Sri tong nak) are examined for the laxative effect on small intestinal transit in rats [2]. The results showed that oral administration of fresh pulp aqueous extracts of a sour tamarind and one sweet tamarind (Kanti) at the dose ranged from 1.6 to 1.8g/kg significantly increased the small intestinal transit in rats when compared with that of the control group (p<0.05). In addition, fresh pulp aqueous extracts from all cultivars elevated peristalsis in isolated rat ileum [3]. However, both effects did not relate to the dose used. Major acids in fresh pulp aqueous extracts are tartaric acid, malic acid and citric acid. The combinations of three acids at the concentration present in fresh pulp aqueous extracts of Preaw-yak and Kanti significantly increased the small intestinal transit in rats when compared with that of the control group (p<0.05). Each acid at the dose of 100mg/kg also caused the increase of small intestinal transit in rats. Our results support the use of fresh pulp of tamarind as laxative in the primary health care suggested by Thai ministry of public health. Acknowledgements: National Research Council of Thailand, Faculty of Pharmacy Chulalongkorn University, Faculty of Medicine, Chiang Mai University. References: 1. Attasit, R. et al. (1990) Herbal medicine in the primary health care. Handbook for public health personnel. Bangkok. War Veterans Organization of Thailand. 2. Parimata-Devi, R. et al. (2002) Phytomed 9:739–742. 3. Madeira, S.V.F.et al. (2002)J Ethnopharmacol 81:1–4.
... The patient was enjoying his day-to-day life very well. [8,9,10,11,12]. According to these modern's perspectives, tamarind acts as an irritant laxative that may be helpful to detach the hard stool from the intestinal mucosa due to its irritant properties, irritates the colon's lining resulting in an increased urgency to pass bowel materials. It also improves liver function & digestion due to anti-oxidant & hepatoprotective properties of the high content of ascorbic acid & B-carotene. ...
... It acts as a good laxative due to high amounts of malic, tartaric, and potassium acid. It increases the Intestinal small transit due to tartaric acid, malic acid, and citric acid extracts [8]. It also eliminates worms due to chronic Constipation by anthelmintic property of tannins present in it [9]. ...
Background: Malavastambha (Constipation) is defined as the infrequent and difficult passage of stool. The main features of Constipation are infrequent or hard stool, abdominal pain, bloating, and feeling of unsatisfactory bowel evacuation. Contemporary laxatives, which are generally used in Constipation, become habitual after some duration and only symptomatic relief. Moreover, these medicines never alter the pathogenesis of the disease. So, it is a need of hour to search effective, safe & alternative formulations in Ayurveda, which can completely break the pathogenesis of Constipation. As per Ayurveda, Vata Dosha is the main factor involved in this condition. Therefore, the prime treatment principle recommended by Ancient Acharyas is to pacify Vata by using Vatahara herbs medicated with Snigdha Dravya, Amla, and Lavana Varga. The Chincha Lavana Taila is one such combination that possesses the above principle & so; it can be effective in Malavastambha. Aim: This case study is primarily carried out to study the role of oral administration of Chincha Lavana Taila in Malavashtambha Objectives: To evaluate the efficacy of oral consumption of Chincha Lavana Taila in Malavastambha. Methods: A single case study. A 50 years old male patient approached Panchakarma O.P.D. with Malavsthambha for one year; he was advised to intake 15ml Chincha Lavana Taila orally at bedtime lukewarm water for consecutive 15 days. Observation and Results: The patient got 100% relief in his all chief & associated complaints and had regular and satisfactory bowel habits after 15 days. Conclusion: Chincha Lavana Taila is one of the best effective oral medicine for Constipation.
... Its use for the relief of constipation has been documented throughout the world including Thailand, Southwest Africa, and Madagascar. [44,45] [24,46] The fruit pulp contains 44.4% of furan derivatives and 38.3% of carboxylic acid derivatives such as tartaric acid, acetic acid, citric acid, formic acid, malic acid, and succinic acid. [47][48][49] It also shows the presence of high amounts of ascorbic acid, β-carotene, lactic acid, Vitamin B1, B3, amino acids, invert sugar (25%-30%), pectin, pyrazines, and some fragrant thiazoles. ...
The view that food can have an expanded role that goes well beyond providing a source of nutrients truly applies to traditional functional foods. The systematic consumption of such traditional functional food provides an excellent preventive measure to ward off many diseases. Rasam, a soup of spices, is a traditional South Indian food. It is traditionally prepared using tamarind juice as a base, with the addition of Indian sesame oil, turmeric, tomato, chili pepper, pepper, garlic, cumin, curry leaves, mustard, coriander, asafoetida, sea salt, and water. Rasam is a classic example of traditional functional food
with all its ingredients medicinally claimed for various ailments. The preclinical and clinical studies on rasam and its ingredients support their traditional claim. This review is an attempt to compile the literatures on rasam, its ingredients, and to highlight its medicinal potential that has been underestimated.
... Its use for the relief of constipation has been documented throughout the world including Thailand, Southwest Africa, and Madagascar. [44,45] [24,46] The fruit pulp contains 44.4% of furan derivatives and 38.3% of carboxylic acid derivatives such as tartaric acid, acetic acid, citric acid, formic acid, malic acid, and succinic acid. [47][48][49] It also shows the presence of high amounts of ascorbic acid, β-carotene, lactic acid, Vitamin B1, B3, amino acids, invert sugar (25%-30%), pectin, pyrazines, and some fragrant thiazoles. ...
The view that food can have an expanded role that goes well beyond providing a source of nutrients truly applies to traditional functional foods. The systematic consumption of such traditional functional food provides an excellent preventive measure to ward off many diseases. Rasam, a soup of spices, is a traditional South Indian food. It is traditionally prepared using tamarind juice as a base, with the addition of Indian sesame oil, turmeric, tomato, chili pepper, pepper, garlic, cumin, curry leaves, mustard, coriander, asafoetida, sea salt, and water. Rasam is a classic example of traditional functional food with all its ingredients medicinally claimed for various ailments. The preclinical and clinical studies on rasam and its ingredients support their traditional claim. This review is an attempt to compile the literatures on rasam, its ingredients, and to highlight its medicinal potential that has been underestimated. © 2017 Pharmacognosy Reviews | Published by Wolters Kluwer - Medknow.
... Oh et al [8] illustrated the efficacy of fig paste for increasing bowel movement in constipated beagles. Panthong et al [9] demonstrated the laxative effect of Tamarindus indica L. in rats. Muri (a kind of drink), Rooster meat pottage and stew with tamarind are considered to be foods beneficial for children susceptible to constipation [10] . ...
PurposePelvic radiotherapy causes permanent changes in the bowel which significantly affects the quality of life of cancer survivors. With advances in oncological treatment modalities, survival of the patients has increased. In such, a scenario the impact of treatment modalities on the quality of life of cancer survivors is all the more important. In this study, we analyze the dietary factors that triggered late gastrointestinal toxicity.Methods
Patients diagnosed as carcinoma uterine cervix and carcinoma endometrium and treated with both pelvic radiation and brachytherapy were included in this study. We telephonically interviewed the patients who had presented with gastrointestinal symptoms using a simple questionnaire which includes symptoms, severity of symptoms, diet prior to onset of symptoms and how the symptoms subsided.ResultsAmong fifty patients evaluated majority presented with abdominal pain and bleeding per rectum. Other symptoms were diarrhea, vomiting and bloating of the abdomen. Also, four patients presented with features of subacute intestinal obstruction. The time of presentation varied from few months to more than five years after pelvic radiation. The major dietary factors that triggered gastrointestinal symptoms include red-chilly, tamarind, red meat (goat, beef) and dried fish. The other dietary factors were maida foods [paratta], nuts [badam], fruits with seeds [pomegranate, guava] and dates.Conclusions
The late gastrointestinal toxicities after pelvic irradiation are grossly underreported. Dietary modifications will be helpful for reducing gastrointestinal symptoms after pelvic radiotherapy.
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