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Vascular dementia:
cortical dysfunctions as functional disturbance of living system hierarchy.
In the past years interest in the topic of dementia has gained significance in the
psychoneurological practise. The tendency may be connected with the fact that patients
contingent with the disease are becoming younger in many European countries. We
were surprised when we received official information about negligible amount (nearly
5%) of vascular dementia among all kinds of dementias. Our experience for the past
years in the diagnostics and treatment of 3 patients with vascular dementia and 37
patients with elements of dementia in the content of postcomatous apallic syndrome
shows that there is another point of view concerning this problem.
USD of arterial and venous vessels (the author’s method by U.B. Lushchyk) in these
patients shows a similar pattern of hemodynamic disturbance on the macrolevel: severe
cerebral arterial deficits, venous cerebral hypertension, and intracranial hypertension.
Besides that, microcirculation level of blood supply considerably decreased according
to the method of smart optical Capillaroscopy.
Thus, total blood supply deficiency on the macrolevel was nearly 50-70% and on the
microlevel residual circulation was nearly 10% of physiological value.
From the point of view of the living system’s functional structure decrease in
intravascular moving pressure with the phenomenon of cerebro-vascular insufficiency
in cortical areas leads to cortical dysfunction.
Multidisciplinary approach to neurorehabilitation of patients with dementia.
The problem of diagnostics, treatment and searching links of pathogenesis of dementia
have become urgent, because the number of patients with this disease tends to be on
the increase. These patients are becoming younger and younger if we see the statistics
of the last decade, which makes us worried.
During 2005-2006 we examined and performed the neurorehabilitation of 3 patients
with dementia: 2 women at the age of 54 and 58 and 1 man at the age of 44.
During the examination the patients showed practically no signs of contact: they didn’t
understand the speech addressed to them, didn’t fulfill instructions, didn’t remember
their names and were slow to recall their relatives. The disease in women begins
slowly; in elder ones it starts after a long-term family stress. Anamnesis of the disease
in the man was unknown, because he had worked in Portugal as a builder and once he
was found on the road by Red Cross members with features of amnesia, disorientation
in place and time.
Our integrated examinations resulted in severe decrease in the hemodynamics both on
macro and micro levels and there was practically no neurodynamic activity and a
sudden decrease in brain tissue reactivity. Psychological and logopedic statuses also
showed various deviations from normal criteria.
All these patients were treated by combinations of various individually selected
medicines simultaneously with the combinations of neurorehabilitation training with
logopedist, psychologist, kinesitherapist, neurorehabilitologist for a one-month period.
All our efforts were directed towards the main aim – to study these patients’ ability to
communicate and look after themselves.
We obtained good results with regressing of the disease features by half. In the first 2
weeks we returned relatives of our patients to their home as these patients became able
to look after themselves and we tried to teach them to communicate with household
appliances inside our clinic.
Besides that, we must draw attention to the problem with the patients’ relatives who
unconsciously help them to become more and more ill, because they restrict all the
patients’ efforts to do any activity as it may be dangerous for the surroundings.
We believe that this disease is a rich prospective field of investigation, further study
and a pathogenetically evident approach to treatment.
We are ready to cooperate with European clinics for the next research project in this
... A new trend in the disease classification and assigning cardiovascular diseases to a group of non-infectious diseases only diverts attention of scientists and doctors from deep study and understanding of changes in the cardiovascular system in the pathogenesis of other diseases on the background of vascular dyshemias -infectious, degenerative diseases, fetal malformations and oncopathology [18,[34][35][36][37][38][39][40][41][42][43]. However, there is a certain progress in statistics-a share of vascular disorders in genesis of vascular dementia has increased from 5% in 2005 to 65-80% in 2013. ...
... It is generally considered that a positive result in treatment testifies to the correct approaches, about innovative technologies, and the unusual results forces to change conservative positions in medicine and at the same time to refute out-of-date axioms about atrophy and brain death [8,37,66]. ...
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Review: Problems of effective correction and radical solving of cardiovascular disorders are not new. However, the statistic indexes of cardiovascular pathology are growing and they are considerably younger [1-6]; this testifies to lack of effective management strategy and tactics in fight against these diseases [7-13]. Today we can make a real estimation of achieved results: for the last 20-30 years many technologies are created for research of vascular system - USD of vessels, МRТ in angiomode; devices for correction of cardiac disorders are widely used - from numerous technologies for estimation of the heart structure to coronarography and coronarshunting; new fields of radical medicine are successfully implemented, such as cardiac surgery, angiosurgery, phlebology [14-16]. And at the same time, regardless of the most up-to-date technologies for vascular diagnostics and angiosurgery cardiovascular diseases gets top ranking regarding morbidity and death rate [6,9,17,18]. It can be explained by the fact that development and introduction in medical practice of modern vascular technologies are behind a steady tendency to progress and cardiovascular diseases strike younger people. This dissonance testifies to insufficient knowledge and analysis at the application of new technological potential of visualization of the cardiovascular system at structural (in vitro and in vivo) and functional level - in vivo [7,9,10,12,17]. Our 20-year-old experience of research of vascular disorders and successful attempts of their correction [19] has shown that 1) There is a huge layer of unexplored hemodynamic parameters, which are important in the personalized treatment processes. However, long neglecting biomechanics in medicine [20] resulted into excessive emphasis on endothelial dysfunction and cellular metamorphosis beneficial for promoting pharmacological business. As a result, doctors are not ready to think logically with categories of circulation mechanics and applied hydro- and hemodynamics [21]. 2) Physicians and medical staff don't have enough knowledge in angiology, hemodynamics, hydrodynamics, analytical angiocorrection, angiotherapy, treatment management on evidential basis. Without understanding the depth of hemodynamic laws and logics of pathological and sanogenic transformations in blood supply for organs and regional reservoirs as closed system of vascular tubes - vascular blood flow, it is impossible to perform personalized adequate treatment and predict positive outcomes [8,10]. 3) There is an urgent need in development of vascular monitoring technologies based on principles of evidential medicine [2,7,8,10]. Monitoring dynamic changes in any medical process management, doctors may correct on time the decline from sanogenic blood restoration in a particular regional reservoir and logic of blood redistribution in different vascular reservoirs in a patient's body. Keywords: Personalized treatment, Hemodynamics, Cardiovascular diseases, Angiocorrection, Hydrodynamic conflicts, Brain edema, Biomarkers, Angiomarkers, Intracranial hypertension, Vascular screening, Angiotherapy
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