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97: Impact of Pre-Transplant Recipient Obesity on Outcomes after Lung Transplantation
... In descriptive terms, overweight and/or obese candidates as a group have tended to have restrictive lung disease and hence receive single-lung grafts, be older, be of male sex, and have a higher lung allocation score. [55][56][57][58] Importantly, Culver et al 59 compared the traditional use of percentage body weight vs BMI to determine the incidence of obesity in this population, as well as determining if one measurement would be a more reliable predictor of outcomes than another. This group found that percentage body weight and BMI did not correlate and that percentage body weight was not useful in predicting outcomes posttransplantation. ...
... Lung Transplantation Weight Studies and Results.[54][55][56][57][58][59][60][61][62][63][64][65][66] ...
The increasing rate of societal obesity is also affecting the transplant world through obesity in candidates and donors as well as its posttransplant repercussions. Being overweight and obese has been shown to have significant effects on both short- and long-term complications as well as patient and graft survival. However, much of the comorbidity can be controlled or prevented with careful patient selection and aggressive management. A team approach to managing obesity and its comorbidities both pre- and posttransplant is essential for successful transplant outcomes. Complicating understanding the results of obesity research is the inclusion different weight categories, use of listing vs transplant weights, patient populations large enough for statistical power, and changes in transplant management, especially immunosuppression protocols, anti-infection protocols, and operative techniques. Much more research is needed regarding many elements, including safe weight loss before transplantation, prevention of weight gain after transplant, genomic influences, and the role of bariatric surgery in the transplant process.
... More recently, we reviewed outcomes of obese patients transplanted in our center in the last 4 years; data has only been presented at an international meeting to date [12]. Obese patients had similar outcomes despite an increased percentage of patients with IPF and increased rates of coronary disease, which would tend to increase the mortality of these patients. ...
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