The triad of iron deficiency anemia, dysphagia, and esophageal membranes, known as Plummer Vinson or Paterson-Kelly Syndrome, occurs infrequently in middle-aged women. Although there are several hypotheses, its pathogenesis is not yet fully defined, with the iron deficiency being the main responsible for the anatomical and functional alterations that occur at the esophageal level. Its main ... [Show full abstract] clinical manifestation is dysphagia, initially intermittent and then progressive, associated with symptoms attributable to iron deficiency, such as coiloniquea, cheilitis, among others. The diagnosis is clinical and imaging; with endoscopy being an essential tool that also allows a therapeutic approach. Its treatment consists of both iron replacement and endoscopic techniques that vary according to the experience and availability of each center. We report two clinical cases with anemia, dysphagia, weight loss, atrophic glossitis and angular cheilitis, which showed the presence of a superior esophageal membrane in the barium esophagogastroduodenal transit and endoscopy. In one of them, the spontaneous rupture was performed when the endoscopy was made; while in the other endoscopic dilation was used by means of a balloon. Both presented immediate resolution of the symptoms and excellent clinical evolution. © 2018, Sociedad Argentina de Gastroenterologia. All rights reserved.