Better science with sex and gender: Facilitating the use of a sex and gender-based analysis in health research

NEXUS, School of Nursing, University of British Columbia, Vancouver, Canada. .
International Journal for Equity in Health (Impact Factor: 1.71). 06/2009; 8(1):14. DOI: 10.1186/1475-9276-8-14
Source: PubMed


Much work has been done to promote sex and gender-based analyses in health research and to think critically about the influence of sex and gender on health behaviours and outcomes. However, despite this increased attention on sex and gender, there remain obstacles to effectively applying and measuring these concepts in health research. Some health researchers continue to ignore the concepts of sex and gender or incorrectly conflate their meanings. We report on a primer that was developed by the authors to help researchers understand and use the concepts of sex and gender in their work. We provide detailed definitions of sex and gender, discuss a sex and gender-based analysis (SGBA), and suggest three approaches for incorporating sex and gender in health research at various stages of the research process. We discuss our knowledge translation process and share some of the challenges we faced in disseminating our primer with key stakeholders. In conclusion, we stress the need for continued attention to sex and gender in health research.

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    • "Experimental studies have demonstrated sex-dependent physiological, morphological, and hormonal differences, and therefore the capability of biological response can be different in both sexes [14]. A number of studies have confirmed sexual dimorphism under pathological and various physiological conditions, underlining the need to include both sexes in the experimental groups. "
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