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Content of a Complete Routine Second Trimester Obstetrical Ultrasound Examination and Report

Authors:

Abstract

To review the benefits of and requirements for a complete second trimester ultrasound and the documentation needed. A complete second trimester ultrasound provides information about the number of fetuses, the gestational age, the location of the placenta, and fetal and maternal anatomy. In the production of this document, the American Institute of Ultrasound in Medicine's "Practice Guideline for the Performance of Obstetric Ultrasound Examinations," the American College of Obstetricians and Gynecologists' practice bulletin, "Ultrasound in Pregnancy," and the Royal College of Obstetricians and Gynaecologists' Working Party Report, "Ultrasound Screening" were reviewed. PubMed and the Cochrane Database were searched using the words "routine second trimester obstetrical ultrasound." The evidence was evaluated using the guidelines developed by the Canadian Task Force on Preventive Health Care. A routine complete second trimester ultrasound between 18 and 22 weeks and a complete ultrasound report will provide the best opportunity to diagnose fetal anomalies and to assist in the management of prenatal care. It will also reduce the number of ultrasound examinations done during the second trimester for completion of fetal anatomy survey. The costs are those involved with the performance of obstetrical ultrasound. This is a revision of previous guidelines; information from other consensus reviews from medical publications has been used. The Society of Obstetricians and Gynaecologists of Canada. 1. Pregnant women should be offered a routine second trimester ultrasound between 18 and 22 weeks' gestation. (II-2B) 2. Second trimester ultrasound should screen for the number of fetuses, the gestational age, and the location of the placenta. (II-1A) 3. Second trimester ultrasound should screen for fetal anomalies. (II-2B).
SOGC CLINICAL PRACTICE GUIDELINE
Content of a Complete Routine Second
Trimester Obstetrical Ultrasound Examination
and Report
Abstract
Objective: To review the benefits of and requirements for a complete
second trimester ultrasound and the documentation needed.
Outcomes: A complete second trimester ultrasound provides
information about the number of fetuses, the gestational age, the
location of the placenta, and fetal and maternal anatomy.
Evidence: In the production of this document, the American Institute
of Ultrasound in Medicine’s “Practice Guideline for the
Performance of Obstetric Ultrasound Examinations,” the American
College of Obstetricians and Gynecologists’ practice bulletin,
“Ultrasound in Pregnancy,” and the Royal College of Obstetricians
and Gynaecologists’ Working Party Report, “Ultrasound
Screening” were reviewed. PubMed and the Cochrane Database
were searched using the words “routine second trimester
obstetrical ultrasound.”
Values: The evidence was evaluated using the guidelines developed
by the Canadian Task Force on Preventive Health Care.
Benefits, Harms, and Costs: A routine complete second trimester
ultrasound between 18 and 22 weeks and a complete ultrasound
report will provide the best opportunity to diagnose fetal anomalies
and to assist in the management of prenatal care. It will also
reduce the number of ultrasound examinations done during the
second trimester for completion of fetal anatomy survey. The costs
are those involved with the performance of obstetrical ultrasound.
Validation: This is a revision of previous guidelines; information
from other consensus reviews from medical publications has been
used.
Sponsors: The Society of Obstetricians and Gynaecologists of
Canada.
Recommendations
1. Pregnant women should be offered a routine second trimester
ultrasound between 18 and 22 weeks’ gestation. (II-2B)
2. Second trimester ultrasound should screen for the number of
fetuses, the gestational age, and the location of the placenta. (II-1A)
3. Second trimester ultrasound should screen for fetal anomalies. (II-2B)
J Obstet Gynaecol Can 2009;31(3):272–275
SECOND TRIMESTER ULTRASOUND
An ultrasound scan performed between 18 and
22 weeks’ gestation provides the pregnant woman and
her care provider with information about multiple aspects
of her pregnancy.1–4 The obstetrical ultrasound will inform
them of and/or confirm the number of fetuses present, the
gestational age, and the location of the placenta. It will pres-
ent an opportunity to diagnose congenital anomalies
and/or to detect soft markers of aneuploidy and to identify
maternal pelvic pathology.
The occurrence of twins undiagnosed at delivery is
extremely rare when women have received a second trimes-
ter ultrasound, and the likelihood of postdates induction
and intrauterine growth restriction significantly decreases.1
In the last two decades, the infant death rate from congenital
272 lMARCH JOGC MARS 2009
SOGC CLINICAL PRACTICE GUIDELINE
This clinical practice guideline has been reviewed by the
Diagnostic Imaging Committee and approved by the Executive
and Council of the Society of Obstetricians and Gynaecologists of
Canada.
The Society of Obstetricians and Gynaecologists of Canada
acknowledges advisory input from the Canadian Association of
Radiologists pertaining to imaging guidelines in the creation of this
document.
PRINCIPAL AUTHORS
Yvonne Cargill, MD, Ottawa ON
Lucie Morin, MD, Montreal QC
DIAGNOSTIC IMAGING COMMITTEE
Lucie Morin (Chair), MD, Montreal QC
Stephen Bly, PhD, Ottawa ON
Kimberly Butt, MD, Fredericton NB
Yvonne Cargill, MD, Ottawa ON
Nanette Denis, RDMS, CRGS, Saskatoon SK
Robert Gagnon, MD, Montreal QC
Marja Anne Hietala-Coyle, RN, Halifax NS
Kenneth Lim, MD, Vancouver BC
Annie Ouellet, MD, Sherbrooke QC
Marie-Hélène Racicot, MD, Montreal QC
Shia Salem, MD, Canadian Association of Radiologists, Toronto ON
Disclosure statements have been received from all members of
the committee.
Key Words: Routine second trimester ultrasound, ultrasound report
No. 223, March 2009 (Replaces No. 103, May 2001)
This document reflects emerging clinical and scientific advances on the date issued and is subject to change. The information
should not be construed as dictating an exclusive course of treatment or procedure to be followed. Local institutions can dictate
amendments to these opinions. They should be well documented if modified at the local level. None of these contents may be
reproduced in any form without prior written permission of the SOGC.
Content of a Complete Routine Second Trimester Obstetrical Ultrasound Examination and Report
MARCH JOGC MARS 2009 l273
Table 1. Content of a Complete Obstetrical Ultrasound Report
Category Required Information
Patient demographic
information Patient name, second patient identifier (birth date, hospital identifier, health insurance number)
Indication for consultation
Requesting physician/caregiver (preferably with contact information)
Starting date of last normal menstrual period (LNMP)
Examination date
Date of written report
Name of interpreting physician
Number of fetuses and
indications of life
Presence of cardiac activity for each fetus
If multiple gestation: chorionicity and amnionicity should be reported
Biometry Should be reported all in millimetres or in centimetres along with equivalent estimated gestational age for:
Biparietal diameter
Head circumference
Abdominal circumference
Femur length
Should be reported in millimetres if abnormal
Nuchal fold
Cisterna magna
Cerebellar diameter
Lateral ventricle width
Fetal anatomy Should be reported as: normal OR abnormal (with details) OR not seen, with explanation
Should be reported for:
Cranium
Cerebral ventricles, cavum septi pellucidi, the midline falx, the choroid plexus
Posterior fossa: cisterna magna, cerebellum
Face: orbits, lips
Spine
Chest
Cardiac four-chamber view
Cardiac outflow tracts
Heart axis
Cardiac situs
Stomach
Bowel
Kidneys
Bladder
Abdominal cord insertion
Number of cord vessels
Upper extremities and presence of hands
Lower extremities and presence of feet
Amniotic fluid amount Should be reported as: normal OR increased OR decreased OR absent
Placenta Position should be reported as well as relationship to the cervical os
Maternal anatomy uterus,
ovaries, cervix, bladder
Should be reported as:
normal OR abnormal with details OR not seen
anomalies has decreased by 50% in infants born after
24 weeks.5This is likely at least partially related to early
diagnosis of congenital anomalies leading to either preg-
nancy termination or better neonatal care. Second trimester
diagnosis of congenital anomalies also provides the
opportunity for fetal therapy.
The literature includes descriptions of anatomical surveys
being performed before 18 weeks6but other studies have
repeatedly shown that more anomalies are diagnosed if the
scan is done after 18 weeks.1,2 A study done by Lantz and
Chisolm7found that in normal sized and in overweight
patients, a fetal anatomy survey for the detection of congen-
ital anomalies was more likely to be incomplete if per-
formed before 18 weeks than if performed at a later gesta-
tional age. In underweight patients, no difference was
found. The Royal College of Obstetricians and Gynaecolo-
gists recommends that the second trimester fetal anatomical
scan be performed between 20 and 23 weeks.8We recom-
mend that the second trimester ultrasound be performed
after 18 weeks and before 22 weeks’ gestation.9This will
allow pregnancy options if an anomaly is diagnosed and
avoid the added cost and unnecessary ultrasound exposure
of a repeat scan related to incomplete fetal anatomy survey.
This is a growing concern, as patients are increasingly likely to
have a high BMI.
When an ultrasound is performed at 18 to 22 weeks’ gesta-
tion, the maternal organs that should be screened are the
cervix, uterus, and adnexa. Any abnormality of these
structures should be documented.
The number of fetuses and the presence of cardiac activity
should be recorded. If a multiple gestation is diagnosed, the
chorionicity and amnionicity should be assessed and
documented.
The fetal biometric measurements should include at least
the following: biparietal diameter, head circumference,
abdominal circumference, and femur length. Absolute bio-
metric measurements with their estimated gestational age
should be documented and reported. A composite esti-
mated gestational age should also be reported, taking into
consideration measurement errors arising from abnormal
fetal body parts. Moreover, the gestational age/size should
be interpreted in correlation with any previous obstetrical
ultrasound if available. This will allow the care provider to
confirm if fetal growth has been appropriate. Due date
should not be adjusted if it has been established by an earlier
ultrasound.
Fetal Anatomy Survey to Be Performed
During a Complete Obstetrical Routine
Second Trimester Ultrasound
The standard fetal brain anatomical survey should
include an assessment and documentation of the following
anatomical landmarks: the shape of the fetal skull, the
cavum septi pellucidi, the midline falx, the choroid plexus,
the lateral cerebral ventricles, the cerebellum, the cisterna
magna, and the nuchal fold. The face should be scanned to
assess and document the orbits and lips.
In the thorax, the heart and lungs should be examined.
Examination of the fetal heart includes its relationship with
the chest (axis, size, and position) as well as the assessment
SOGC CLINICAL PRACTICE GUIDELINE
274 lMARCH JOGC MARS 2009
Table 2. Key to evidence statements and grading of recommendations, using the ranking of the
Canadian Task Force on Preventive Health Care
Quality of Evidence Assessment* Classification of Recommendations†
I: Evidence obtained from at least one properly randomized
controlled trial
II-1: Evidence from well-designed controlled trials without
randomization
II-2: Evidence from well-designed cohort (prospective or
retrospective) or case-control studies, preferably from more
than one centre or research group
II-3: Evidence obtained from comparisons between times or
places with or without the intervention. Dramatic results in
uncontrolled experiments (such as the results of treatment
with penicillin in the 1940s) could also be included in this
category
III: Opinions of respected authorities, based on clinical
experience, descriptive studies, or reports of expert
committees
A. There is good evidence to recommend the clinical preventive
action
B. There is fair evidence to recommend the clinical preventive
action
C. The existing evidence is conflicting and does not allow to
make a recommendation for or against use of the clinical
preventive action; however, other factors may influence
decision-making
D. There is fair evidence to recommend against the clinical
preventive action
E. There is good evidence to recommend against the clinical
preventive action
L. There is insufficient evidence (in quantity or quality) to make
a recommendation; however, other factors may influence
decision-making
*The quality of evidence reported in these guidelines has been adapted from The Evaluation of Evidence criteria described in the Canadian Task Force
on Preventive Health Care.11
†Recommendations included in these guidelines have been adapted from the Classification of Recommendations criteria described in the The Canadian
Task Force on Preventive Health Care.11
of the four chamber view and the relationships of the out-
flow tracts. The fetal cardiac motion should be observed
and a fetal heart rate recorded. The lungs should be exam-
ined for their echogenicity.
In the fetal abdomen, the anatomical survey should
include the position, presence, and situs of the stomach,
and visualization of the bowel, bladder, kidneys, cord inser-
tion, and number of cord vessels.
The fetal spine should be viewed throughout its length in
sagittal, coronal, and transverse planes if possible. The skin
line should be seen away from the uterine wall. This cannot
always be documented with still images.
An attempt should be made to assess the fetal genitalia.
All four limbs to the level of the hands and feet should be
visualized, and the presence of hands and feet should be
noted. Subjective assessment of bone size, shape, and den-
sity should be done. This cannot always be documented
with still images.
The placenta should be examined for position, appear-
ance, and presence or absence of abnormalities. The placen-
tal location and its relationship to the internal cervical os
should be assessed and documented.
A qualitative assessment of the amniotic fluid volume
should be made. It should be reported as normal, increased,
decreased, or absent.
Table 1 shows the recommended content of the report, but
other information may be provided in such consultations.
The ultrasound report should include all ultrasound infor-
mation necessary for appropriate management of the preg-
nancy. It needs to include the date the scan was performed
and the composite gestational age based on fetal biometric
measurements. The number and size of fetuses and the
measurements obtained to determine them should be
noted. If a structure was not seen, this should be reported,
along with the reason it was not seen. If fetal or maternal
abnormalities are reported, a differential diagnosis and,
when appropriate, a recommendation for further investiga-
tion should be provided. The report should comment on
any significant technical difficulty of the examination. The
final report should be easy to read.
It is acknowledged that even in the best of hands and cir-
cumstances, the 18–22 week scan has limitations and can-
not detect all fetal and maternal abnormalities.10
Any significant fetal or maternal abnormalities need to be
reported promptly to the caregiver. The communication
should be recorded in the patient’s file.
An ultrasound report summary should provide:
Estimation of gestational age according to ultrasound if
this is the first obstetrical ultrasound, estimation of
gestational age according to last menstrual period dates,
and the expected date of confinement
Appropriateness of the biometry, size, growth, and
estimated gestational age
Summary of findings
Differential diagnosis if indicated
Recommendations for further investigations and
referral for tertiary centre assessment when necessary.
Recommendations
The evidence was evaluated using the guidelines developed
by the Canadian Task Force on Preventive Health Care
(Table 2).
1. Pregnant women should be offered a routine second
trimester ultrasound between 18 and 22 weeks’
gestation. (II-2B)
2. Second trimester ultrasound should screen for the
number of fetuses, the gestational age, and the location
of the placenta. (II-1A)
3. Second trimester ultrasound should screen for fetal
anomalies. (II-2B)
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3. ACOG Committee on Practice Bulletins. ACOG Practice Bulletin, No. 58,
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4. Seeds JW. The routine screening obstetrical ultrasound examination.
Clin Obstet Gynecol 1996;39(4):814–30.
5. Liu S, Joseph KS, Wen SW. Trends in fetal and infant deaths caused by
congenital anomalies. Semin Perinatol 2002;26(4):268–76.
6. Souka AP, Pilalis A, Kavalakis I, Antsaklis P, Papantoniou N, Mesogitis S,
et al. Screening for major structural abnormalities at the 11- to 14- week
ultrasound scan. Am J Obstet Gynecol 2006;194(2):393–6.
7. Lantz ME, Chisolm CA. The preferred timing of second-trimester
sonography based on maternal body mass index. J Ultrasound Med
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8. Whittle MJ, Chitty LS, Neilson JP, Shirley, Smith IM, Ville YG, et al.;
National Working Party, Royal College of Obstetricians and
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Content of a Complete Routine Second Trimester Obstetrical Ultrasound Examination and Report
MARCH JOGC MARS 2009 l275
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Multiple evidence support the prenatal predisposition of autism spectrum disorder (ASD). Nevertheless, robust data about abnormalities in fetuses later developing into children diagnosed with ASD are lacking. Prenatal ultrasound is an excellent tool to study abnormal fetal development as it frequently used to monitor fetal growth and identify fetal anomalies throughout pregnancy. We conducted a retrospective case-sibling-control study of children diagnosed with ASD (cases); their own typically developing, closest-in-age siblings (TDS); and typically developing children from the general population (TDP), matched by year of birth, sex and ethnicity to investigate the association between ultrasonography fetal anomalies (UFAs) and ASD. The case group was drawn from all children diagnosed with ASD enrolled at the Azrieli National Center of Autism and Neurodevelopment Research. Fetal ultrasound data from the fetal anatomy survey were obtained from prenatal ultrasound clinics of Clalit Health Services (CHS) in southern Israel. The study comprised 659 children: 229 ASD, 201 TDS, and 229 TDP. UFAs were found in 29.3% of ASD cases vs. only 15.9% and 9.6% in the TDS and TDP groups (aOR = 2.23, 95%CI = 1.32-3.78, and aOR = 3.50, 95%CI = 2.07-5.91, respectively). Multiple co-occurring UFAs were significantly more prevalent among ASD cases. UFAs in the urinary system, heart, and head&brain were the most significantly associated with ASD diagnosis (aORUrinary =2.08, 95%CI = 0.96-4.50 and aORUrinary = 2.90, 95%CI = 1.41-5.95; aORHeart = 3.72, 95%CI = 1.50-9.24 and aORHeart = 8.67, 95%CI = 2.62-28.63; and aORHead&Brain = 1.96, 95%CI = 0.72-5.30 and aORHead&Brain = 4.67, 95%CI = 1.34-16.24; vs. TDS and TDP, respectively). ASD females had significantly more UFAs than ASD males (43.1% vs. 25.3%, p = 0.013) and a higher prevalence of multiple co-occurring UFAs (15.7% vs. 4.5%, p = 0.011). No sex differences were seen among TDS and TDP controls. ASD fetuses were characterized by a narrower head and a relatively wider ocular-distance vs. TDP fetuses (ORBPD = 0.81, 95%CI = 0.70-0.94, and aOROcular-Distance = 1.29, 95%CI = 1.06-1.57). UFAs were associated with more severe ASD symptoms. Our findings shed important light on the abnormal multiorgan embryonic development of ASD and suggest fetal ultrasonography biomarkers for ASD.
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Background: We sought to examine the diagnostic yield of current fetal echocardiography (FE) indications representing a recent era. Methods: We examined the FE reports of all pregnancies referred to two provincial FE programs in 2009-2018, identifying the indication for FE (14 categories), gestational age at referral, and whether there was 1) no fetal heart disease (FHD), 2) mild/possible FHD (e.g., simple ventricular septal defect, possible coarctation), or 3) moderate/severe FHD. Results: Over the study period, there were 19,310 unique FE referrals in Alberta (23.3±5.4 weeks gestation), including 1907 (9.9%) with moderate/severe and 654 (3.4%) with mild/possible FHD. The most common referral indications included: extracardiac pathology/markers (29.7%), maternal diabetes (18.3%), suspected FHD and family history of heart defects (17.7% each). Highest yield for moderate/severe FHD was suspected FHD (41.1%; 95% confidence interval: 39.4, 42.7%), followed by suspected/confirmed genetic disorder (15.4%; 12.6, 18.2%), twins/multiples (10.6%; 8.7, 12.5%), oligohydramnios (8.0%; 4.1, 11.9%), extracardiac pathology/markers (6.4%; 5.8, 7.1%) and heart not well seen (5.8%; 4.0, 7.6%). Lowest yields were observed in maternal diabetes (2.2%; 1.7, 2.7%) and family history of heart defects (1.7%; 1.3, 2.2%). Excluding suspected FHD, with >2 FE indications all other indications demonstrated a significant increase in yield of mild/possible (3.5% vs 1.9%, p<0.001) and moderate/severe (7.2% vs 2.9%, p<0.001) FHD. Conclusions: Suspected FHD provides the highest diagnostic yield of moderate/severe FHD. In contrast, maternal diabetes and family history of heart defects, among the most common referral indications, had diagnostic yields approaching general population risks. Even in the absence of suspected FHD, having >2 referral indications importantly increases the diagnostic yield of all other FE indications.
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Ultrasound is an imaging modality that is highly operator dependent. This article reviews the challenges in learning how to perform obstetric sonography, as well as the processes necessary to acquire expert performance skills in sonography. Simulation-based education and learning, and the value of medical simulation are also discussed. Ultrasound simulators are an effective means of teaching obstetric sonography, because it provides training, deliberate practice, and performance evaluation/feedback which allows continuous and critical self-evaluation. We review evidence that simulation can improve performance in obstetric ultrasound examination, review current simulators, and discuss the current problems/gaps in ultrasound simulation. Optical positioning ultrasound simulation is a novel high-fidelity simulation learning system, which addresses many of these problems/gaps and is introduced for the first time here.
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Background: Diagnostic ultrasound is a sophisticated electronic technology, which utilises pulses of high frequency sound to produce an image. Diagnostic ultrasound examination may be employed in a variety of specific circumstances during pregnancy such as after clinical complications, or where there are concerns about fetal growth. Because adverse outcomes may also occur in pregnancies without clear risk factors, assumptions have been made that routine ultrasound in all pregnancies will prove beneficial by enabling earlier detection and improved management of pregnancy complications. Routine screening may be planned for early pregnancy, late gestation, or both. The focus of this review is routine early pregnancy ultrasound. Objectives: To assess whether routine early pregnancy ultrasound for fetal assessment (i.e. its use as a screening technique) influences the diagnosis of fetal malformations, multiple pregnancies, the rate of clinical interventions, and the incidence of adverse fetal outcome when compared with the selective use of early pregnancy ultrasound (for specific indications). Search strategy: We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (September 2009). Selection criteria: Published, unpublished, and ongoing randomised controlled trials that compared outcomes in women who experienced routine versus selective early pregnancy ultrasound (i.e. less than 24 weeks' gestation). We have included quasi-randomised trials. Data collection and analysis: Two review authors independently extracted data for each included study. We used the Review Manager software to enter and analyse data. Main results: Routine/revealed ultrasound versus selective ultrasound/concealed: 11 trials including 37505 women. Ultrasound for fetal assessment in early pregnancy reduces the failure to detect multiple pregnancy by 24 weeks' gestation (risk ratio (RR) 0.07, 95% confidence interval (CI) 0.03 to 0.17). Routine scan is associated with a reduction in inductions of labour for 'post term' pregnancy (RR 0.59, 95% CI 0.42 to 0.83). Routine scans do not seem to be associated with reductions in adverse outcomes for babies or in health service use by mothers and babies. Long-term follow up of children exposed to scan in utero does not indicate that scans have a detrimental effect on children's physical or cognitive development. Authors' conclusions: Early ultrasound improves the early detection of multiple pregnancies and improved gestational dating may result in fewer inductions for post maturity. Caution needs to be exercised in interpreting the results of aspects of this review in view of the fact that there is considerable variability in both the timing and the number of scans women received.
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Many clinicians advocate routine ultrasound screening during pregnancy to detect congenital anomalies, multiple-gestation pregnancies, fetal growth disorders, placental abnormalities, and errors in the estimation of gestational age. However, it is not known whether the detection of these conditions through screening leads to interventions that improve perinatal outcome. We conducted a randomized trial involving 15,151 pregnant women at low risk for perinatal problems to determine whether ultrasound screening decreased the frequency of adverse perinatal outcomes. The women randomly assigned to the ultrasound-screening group underwent one sonographic examination at 15 to 22 weeks of gestation and another at 31 to 35 weeks. The women in the control group underwent ultrasonography only for medical indications, as identified by their physicians. Adverse perinatal outcome was defined as fetal death, neonatal death, or neonatal morbidity such as intraventricular hemorrhage. The mean numbers of sonograms obtained per woman in the ultrasound-screening and control groups were 2.2 and 0.6, respectively. The rate of adverse perinatal outcome was 5.0 percent among the infants of the women in the ultrasound-screening group and 4.9 percent among the infants of the women in the control group (relative risk, 1.0; 95 percent confidence interval, 0.9 to 1.2; P = 0.85). The rates of preterm delivery and the distribution of birth weights were nearly identical in the two groups. The ultrasonographic detection of congenital anomalies had no effect on perinatal outcome. There were no significant differences between the groups in perinatal outcome in the subgroups of women with post-date pregnancies, multiple-gestation pregnancies, or infants who were small for gestational age. Screening ultrasonography did not improve perinatal outcome as compared with the selective use of ultrasonography on the basis of clinician judgment.
Article
The debate concerning the value of routine screening ultrasound in the low-risk patient continues. The most likely benefits are obstetrical, with confirmation of dates, detection of multiple gestation, baseline growth data, and location of the placenta being primary advantages gained from such an examination. The detection of the unexpected major fetal malformation has always been the least likely benefit of routine ultrasound. Furthermore, the majority of reports have been retrospective, uncontrolled, and too small to resolve the question. The RADIUS study was intended to solve these problems, but suffered from such intense selection that the final population for study had little need for medical care at all and little relevance to the average population. The rate of adverse outcomes among the control group was so low that few interventions would appear useful. Furthermore, the analysis of the RADIUS data appeared to suggest bias by underestimating the diagnostic sensitivity of ultrasound for major anomalies, and de-emphasizing those statistically significant obstetrical benefits that were recorded. An attempt at cost-benefit analysis by the RADIUS study misrepresented the cost of routine ultrasound by overestimating the size of the low-risk population, arbitrarily costing out two scans instead of one, and therefore overestimated the cost savings of omitting these examinations. Diagnostic sensitivity of the screening obstetrical ultrasound examination appears to be highest in high-risk patients examined by highly specialized ad experienced personnel that may be of limited availability. diagnostic sensitivity may be quite good, however, even in low-risk patients with a basic or routine examination if recognized guidelines for content are followed and referral to experienced referral resources for unclear or suspicious images is liberally practiced. Optimal service and minimum liability exposure will result if the following guidelines are followed: 1. The obstetric population should be carefully screened for historical or clinical risk factors that might indicate increased probability of fetal abnormality. Identification of such increased risk should cause consideration of referral. 2. The screening ultrasound examination should be methodical and complete and include examination of each of several recommended scanplane views to maximize diagnostic sensitivity. 3. The performance of a complete and methodical examination should be carefully documented with both descriptive text and image records to show that a standard of care service was provided. 4. Referral for second opinion should be easily considered and easily obtained in the case of any suspicious finding. Should every obstetrical patient have an ultrasound examination? Only if it is competently performed, properly recorded, and if the patient is aware of appropriate goals and limitations. The ideal gestational age is between 18 and 22 completed weeks.
Article
Advantages of early pregnancy ultrasound screening are thought to be more accurate calculation of gestational age, earlier identification of multiple pregnancies, and diagnosis of non-viable pregnancies and certain fetal malformations. The objective of this review was to assess the use of routine (screening) ultrasound compared with the selective use of ultrasound in early pregnancy (ie before 24 weeks). The Cochrane Pregnancy and Childbirth Group trials register and the Cochrane Controlled Trials Register (up to July 1998) were searched. Adequately controlled trials of routine ultrasound imaging in early pregnancy. One reviewer assessed trial quality and extracted data. Study authors were contacted for additional information. Nine trials were included. The quality of the trials was generally good. Routine ultrasound examination was associated with earlier detection of multiple pregnancies (twins undiagnosed at 26 weeks, odds ratio 0.08, 95% confidence interval 0.04 to 0.16) and reduced rates of induction of labour for post-term pregnancy (odds ratio 0. 61, 95% confidence interval 0.52 to 0.72). There were no differences detected for substantive clinical outcomes such as perinatal mortality (odds ratio 0.86, 95% confidence interval 0.67 to 1.12). Where detection of fetal abnormality was a specific aim of the examination, the number of terminations of pregnancy for fetal anomaly increased. Routine ultrasound in early pregnancy appears to enable better gestational age assessment, earlier detection of multiple pregnancies and earlier detection of clinically unsuspected fetal malformation at a time when termination of pregnancy is possible. However the benefits for other substantive outcomes are less clear.
Article
Understanding the causes that underlie the recent dramatic declines in infant deaths caused by congenital anomalies requires an appreciation of trends in cause-specific infant mortality, and especially trends in gestational age-specific and cause-specific fetal mortality. This article examines temporal changes in gestational age-specific and cause-of-death-specific fetal mortality rates in Canada, congenital anomaly-related infant mortality rates in Canada, England and Wales, and the United States, and cause-of-death-specific infant mortality rates in Canada and the United States. Fetal deaths caused by congenital anomalies at very early gestation (20-25 weeks) have increased dramatically in recent years, while fetal and infant deaths at later gestations have declined. Prenatal diagnosis and selective termination of pregnancies affected by congenital anomalies appears to be the major factor responsible for the accelerated decline in infant deaths. Further declines in overall infant mortality in industrialized countries can be expected as a result of an increasing uptake of prenatal diagnosis.
Article
To determine the preferred timing of sonographic screening of fetal anatomy based on the maternal body mass index (BMI). We abstracted the sonographic reports of 2,303 gravidas undergoing routine fetal anatomic screening between 15 and 24 weeks' gestation to determine the completeness of the study. Height and weight information was available on 1444 patients. The maternal BMI (weight [kilograms]/height [square meters]) was categorized as underweight (<19.8), normal weight (19.8-26.0), overweight (26.1-29.0), and obese (>29.0). Completion rates were compared by chi(2) analysis. Multiple logistic regression was used to evaluate for independent predictors of a completed study. Except for underweight women, completion rates for all BMI categories were significantly higher when the sonographic examinations were performed between 18 weeks and 19 weeks 6 days compared with those performed between 15 weeks and 17 weeks 6 days. Body mass index, estimated gestational age, and black race were independent predictors of a completed study. Except in underweight women, the 18- to 20-week interval appears to be superior to the 15- to 18-week interval when performing sonographic screening of the fetal anatomy.
Article
The purpose of this study was to examine the value of performing a detailed examination of the fetus as part of the routine 11 to 14 weeks' ultrasound scan in a 2-stage screening process for major structural defects in low-risk pregnancies. This was a prospective study in 1148 singleton pregnancies at 11 to 14 weeks of gestation using a combination of transabdominal and transvaginal sonography to estimate the sensitivity of the first and second trimester ultrasound scan in the detection of major anomalies. Seven of the 14 major anomalies were detected at the 11 to 14 weeks scan, and an additional 6 at the second trimester scan. The sensitivity of the early anatomic examination and the overall sensitivity of the 2-stage screening were 50% and 92.8%, respectively. Nuchal translucency was increased in 5 of the 14 (35.7%) abnormal fetuses and in 1 of the 4 cases (25%) with major heart defects. Detailed, structured examination of fetal anatomy during the routine 11 to 14 weeks' scan can detect half of major structural defects in low-risk pregnancies.
Adult obesity in Canada: measured height and weight
  • M Tjepkema
Tjepkema M. Adult obesity in Canada: measured height and weight. Statistics Canada, 82-620-MWE/2005001.