Primary mediastinal malignant meningioma

Department of Thoracic Surgery, The Northern Hospital, Shenyang, Liaoning, China.
European journal of cardio-thoracic surgery: official journal of the European Association for Cardio-thoracic Surgery (Impact Factor: 3.3). 05/2009; 36(1):217-8. DOI: 10.1016/j.ejcts.2009.03.040
Source: PubMed


Primary ectopic meningiomas are extremely rare tumors of controversial origin and they are usually limited to the head and
neck region. Its occurrence at the mediastinum is even rarer. There has not been any official report regarding primary mediastinal
malignant meningioma until today. Because of its rarity and potential value, we report here a case of primary mediastinal
malignant meningioma, which turns out to be the first reported case of this type of meningioma. The clinical features, treatment
plans, pathological findings, as well as prognosis of a case of primary mediastinal malignant meningioma were carefully analyzed
and the literature on ectopic meningioma was reviewed. The diagnosis of ectopic meningioma can only be established based on
microscopic and immunohistochemical findings. Surgery is the treatment of choice for ectopic meningioma and postoperative
radiotherapy should be managed for patients with suspected invasive meningioma.

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