Agenesis of the Dorsal Pancreas and Its Association With Pancreatic Tumors

Surgery, Saint Barnabas Medical Center, Livingston, NJ, USA.
Pancreas (Impact Factor: 2.96). 06/2009; 38(4):367-73. DOI: 10.1097/MPA.0b013e318196c401
Source: PubMed


Morphogenesis of the pancreas is a complex process; nevertheless, congenital anomalies are rare. At embryogenesis, the pancreas develops from the endoderm-lined dorsal and ventral buds of the duodenum. The ventral bud gives rise to the lower head and uncinate process of the pancreas; whereas, the dorsal bud gives rise to the upper head, isthmus, body, and tail of the pancreas. Rarely, developmental failure of the dorsal pancreatic bud at embryogenesis results in the agenesis of the dorsal pancreas--neck, body, and tail. Even rarer is the association of pancreatic tumors with agenesis of the dorsal pancreas. In addition to citing our case, we provide a comprehensive review on agenesis of the dorsal pancreas and its association with pancreatic tumors.

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