Community-Led Total Sanitation (CLTS) is a radically new participatory approach to rural sanitation. In this overview article the guest editors explore how CLTS has shown promising results where previous rural sanitation programmes in Africa have failed. Although the approach has only been rolled out in Africa in the last three years, the pace with which it has been taken up and developed is astonishing. Over 2.6 billion of the world's population do not have proper toilet facilities. As a result, diarrhoea and disease kill around 1.8 million people every year, mainly children under the age of five. Yet CLTS has started to encourage people to break the silence around sanitation and bring shit out into the open. It does so by explicitly talking about and making visible the shit that is normally hidden beneath taboos and polite language. Past approaches to rural sanitation were mostly based on subsidised hardware. Unlike traditional sanitation approaches, CLTS works without subsidies for individual households. Instead, CLTS uses PRA tools to mobilise communities' collective action to become open defecation free - literally shit free. This does not happen through education, force or monetary incentives, but through the facilitation of a participatory process called 'triggering' that raises awareness and mobilises collective action for change. CLTS emphasises, as long as even a minority still defecates in the open, all members of the community are 'eating each others' shit' and are at risk of disease. CLTS is about people, their attitudes and behaviour, rather than hardware or structures. However, it is not only communities whose behaviour change is required - facilitators, institutions, governments and development practitioners, too, are challenged to think and act differently. Here, the authors look at some of the issues, challenges and lessons learnt. The article examines how CLTS has developed: how it differs from other sanitation approaches, its key elements and conditions for success, and emerging issues and questions in Africa and elsewhere. It looks at community-level processes in CLTS, from innovative forms of triggering, to the importance of language, building on an understanding of local taboos, and the potential of CLTS to empower children and youth. It identifies challenges when scaling up and considers some of the management and organisational changes needed for CLTS to be effective as well as the opportunities, challenges and lessons for taking CLTS to scale, based on experiences so far in Africa. The authors also discuss the importance of quality training and facilitation, identifying CLTS champions and natural leaders, engaging with government and ensuring multi-sector involvement. Issues around verification, certification and follow-up activities that ensure sustainability, and ongoing activities to mobilise further community development are also examined. The authors conclude that documentation and sharing of experiences amongst practitioners needs to be encouraged so that lessons will not be lost but will instead help to continuously improve CLTS practice and policy.