Complex Trauma and Disorders of Extreme Stress (DESNOS) Diagnosis, Part Two: Treatment

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D i r ections in P s y c h i a t r y
LESSON 25
Complex Trauma and Disorders of Extreme Stress
(DESNOS) Diagnosis, Part One: Assessment
Toni Luxenberg, PsyD, Joseph Spinazzola, PhD, and Bessel A. van der Kolk, MD
LESSON 26
Complex Trauma and Disorders of Extreme Stress
(DESNOS) Diagnosis, Part Two: Treatment
Toni Luxenberg, PsyD, Joseph Spinazzola, PhD, Jose Hidalgo, MD, Cheryl Hunt, PsyD,
and Bessel A. van der Kolk, MD
Contents
373
395
Volume 21 2001
Lessons 25 & 26
The enclosed lessons are part of the curriculum for psychiatrists
p a rticipating in the Directions in Psychiatry home-study CME
p r og r am published by The Hatherleigh Company, L t d . © 2001
For more information about the Directions prog ra m s, please visit
w w w. h a t h e r l e i g h . c o m • Ke y wo rd : p s y c h i a t ry

373
Complex Trauma and
Disorders of Extreme Stress
(DESNOS) Diagnosis,
Part One: Assessment
Toni Luxenberg, PsyD, Joseph Spinazzola, PhD,
and Bessel A. van der Kolk, MD
Dr. Luxenberg is a Supervisor and Staff Psychologist, Dr. Spinazzola is the Associate Director of Research
and a Staff Psychologist, and Dr. Van der Kolk is the Medical Director of The Trauma Center,
Arbour Health System, Allston, MA, and Boston University School of Medicine.
The authors would like to acknowledge Margaret Blaustein, PhD, for her contributions to this manuscript.
Learning Objective
Clinicians will learn to understand the progressive developmental impact of traumatic experiences
that compromise ongoing psychological, biological, and social maturation and lead to a diagnosis of
Complex PTSD or Disorders of Extreme Stress, Not Otherwise Specified (DESNOS). They will also
learn to recognize the clinical symptomatology of this condition and how to assess patients for it.
The diagnostic concept of Post Traumatic Stress Disorder was first introduced into DSM-III in the mid-l970s, rep-
resenting a major step forward in our definition and understanding of psychiatric conditions. Since then, various
modifications have been introduced, such as Acute Stress Disorder (ASD) and Complex PTSD or Disorders of
Extreme Stress, Not Otherwise Specified (DESNOS), in order to more precisely identify etiological issues and tar-
get early, effective interventions.
D i r e c t i o n s i n P s y c h i a t r y
Volume 21 Lesson 25
Editor’s Note
Publication Date: November, 2001

Introduction
In the middle of the 1970s, when Post Traumatic
Stress Disorder (PTSD) was first proposed for inclu-
sion in the Diagnostic and Statistical Manual of Mental
Disorders, Third edition, (DSM-III), only a sparse lit-
erature on “traumatic neuroses” was available to guide
the creation of a diagnostic construct for PTSD.
1
The
DSM-III PTSD committee depended mainly on the
existing literature on traumatized male adults––com-
bat veterans
2,3
and holocaust survivors.
4
Beginning
even before the publication of the DSM-III, in 1980,
rapidly growing research literature confirmed the rele-
vance of PTSD as a diagnostic construct, applicable to
a large variety of traumatized populations, such as rape
survivors, abused children, refugees, and survivors of
accidents, disasters, and domestic violence.
5
The mod-
ification of the PTSD definition in the DSM-III-R
reflected the incorporation of evolving research find-
ings and theoretical formulations into psychiatric
nomenclature.
6–8
Indeed, research in the past two
decades has firmly established the high prevalence of
PTSD and its potentially debilitating impact on the
lives of individuals. Epidemiological research has
shown that the majority of individuals experience
at least one traumatic event during their life, and
up to a quarter of those individuals will ultimately
develop PTSD.
9,10
The relevance of trauma has begun to permeate our
culture’s popular awareness, but a large body of
research investigating the effects of trauma on psycho-
logical functioning has shown that PTSD captures
only a limited aspect of post-traumatic psy-
chopathology.
11–13
One critical element in determin-
ing psychopathology outcomes is the developmen-
tal level at which the trauma occurs and whether it
occurs in the context of a relationship with a care-
giver or intimate partner. For example, victims of
car accidents and natural disasters often have quite
different clinical presentations than those who
experienced abuse, deprivation, and/or neglect at
the hands of their caregivers. In addition, the age at
which the trauma occurred also shapes subsequent
adaptation patterns. While the symptomatology of
victims of single-incident traumas are fairly well cap-
tured in the DSM-IV diagnosis of PTSD, victims of
interpersonal trauma present with a more complex
picture.
12–19
This lesson will explore the concept of D i s o rd e r s
of Ex t reme St r ess Not Ot h e rwise Sp e c i f i e d
(DESNOS), which has a symptom constellation
delineated in the DSM-IV under “associated feature s
of PTSD.” Though DESNOS is not currently a dis-
tinct diagnosis identified in the DSM-IV, its symptom
constellation has been identified in numerous re s e a rc h
studies and is currently being re s e a rched and considere d
for inclusion, as a free-standing diagnosis, in the DSM-
I V. We will begin by examining the differe n c e s
b e t ween PTS D (as defined in the DSM-IV) and the
associated features of PTSD—DESNOS. The com-
ponents of DESNOS will be explored in depth. Ne x t ,
we will discuss various means of assessing DESNOS
that can be integrated into practice. Fi n a l l y, a phase-ori-
ented model of treatment will be presented, and a num-
ber of therapeutic techniques to use in the stabilization
of these challenging patients will be discussed.
PTSD Diagnostic Criteria
For an individual to be diagnosed with PTSD, he
or she must: have experienced an event in which
the life, physical safety, or physical integrity of the
patient or another person was threatened or actu-
ally damaged; and the patient must have experi-
enced intense fear, helplessness, or horror in
response; continue to reexperience the traumatic
event after it is over (e.g., flashbacks, nightmares,
intrusive thoughts, and emotional and physiological
distress in the face of reminders of the event); seek to
avoid reminders of the event (e.g., avoidance of
374
Volume 21 Lesson 25Directions in Psychiatry
Characteristic of DESNOS is trauma which involves interpersonal victimization, multiple traumatic events, or
events of prolonged duration. Disturbances in six areas of functioning are required for the diagnosis: (1) regulation
of affect and impulses; (2) attention or consciousness; (3) self-perception; (4) relations with others; (5) somatiza-
tion; and (6) systems of meaning. The authors offer clinical examples of each of these and go on to describe psy-
chometric tests that can be used as valuable diagnostic aides.

thoughts, feelings, and conversations about the event;
avoidance of people, places, and activities that are
associated with the event; difficulty recalling aspects
of, or the totality of the event; diminished interest in
formerly pleasurable activities; feelings of detachment;
and a sense of a foreshortened future); exhibit signs
of persistent arousal (e.g., difficulty with sleep,
increased irritability, concentration problems, scan-
ning of environment for danger, and heightened star-
tle responses).
DESNOS Criteria
In exploring the disparate adaptations to complex
trauma, the DSM-IV PTSD taskforce
21
highlighted
alterations in six areas of functioning for the diag-
nosis of DESNOS: (1) regulation of affect and
impulses; (2) attention or consciousness; (3) self-
perception; (4) relations with others; (5) somatiza-
tion; and (6) systems of meaning (Table 1). The
PTSD taskforce also discussed alteration in one’s view
of the perpetrator, but this was not considered a
mandatory aspect of the diagnosis of DESNOS. We
will examine each of these six areas in turn in the sec-
tion “Aspects of DESNOS.”
While DESNOS is not officially predicated on spe-
cific traumatic experiences, both clinical consensus
and research in the field have linked the DESNOS
diagnosis with histories of interpersonal victimiza-
tion, multiple traumatic events, and/or traumatic
exposure of extended duration. Awareness of the
characteristic backgrounds of individuals who meet
criteria for DESNOS will aid in effective case concep-
tualization and treatment planning. Often these indi-
viduals have histories of a large variety of traumatic
events, spanning years and even decades. Such indi-
viduals may not have had discrete traumatic experi-
ences so much as ongoing, chronic exposure to unten-
able environments. An example of a typical DESNOS
history would be a woman who reports that she was
never held as a child and was sexually abused through-
out her childhood by her alcoholic father, who also
physically assaulted her mother in her presence. Even
when sober, her father frequently called her names and
insulted her intelligence, attractiveness, and capabili-
ties. As an adolescent, she may have witnessed the seri-
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part One: Assessment Luxenberg, Spinazzola, & van der Kolk
375
Tab le 1
DIAGNOSTIC CRITERIA FOR
DISORDERS OF EXTREME STRESS
(DESNOS)
A
I. Alteration in Regulation of Affect and Impulses
(A and 1 of B–F required):
A. Affect Regulation (2)
B. Modulation of Anger (2)
C. Self-Destructive
D. Suicidal Preoccupation
E. Difficulty Modulating Sexual Involvement
F. Excessive Risk-taking
II. Alterations in Attention or Consciousness
(A or B required):
A. Amnesia
B. Transient Dissociative Episodes and
Depersonalization
III. Alterations in Self-Perception
(Two of A–F required):
A. Ineffectiveness
B. Permanent Damage
C. Guilt and Responsibility
D. Shame
E. Nobody Can Understand
F. Minimizing
IV. Alterations in Relations With Others
(One of A–C required):
A. Inability to Trust
B. Revictimization
C. Victimizing Others
V. Somatization
(Two of A–E required):
A. Digestive System
B. Chronic Pain
C. Cardiopulmonary Symptoms
D. Conversion Symptoms
E. Sexual Symptoms
VI. Alterations in Systems of Meaning
(A or B required):
A. Despair and Hopelessness
B. Loss of Previously Sustaining Beliefs
A
Numbers in parentheses indicate number of subscale
items required for endorsement of subscale. Only one
item required for endorsement of all other subscales.

ous injury of several friends during a drunk-driving
accident. As an adult, this woman may have been
raped and had a series of emotionally and physically
abusive partners. A history of chronic traumatization,
however, will not always lead to the development of
DESNOS symptomatology. We will now turn to an
exploration of the conceptual evolution from PTSD to
DESNOS.
The Co-Occurrence of PTSD
and Other Disorders: The
Concept of DESNOS
It has been noted in numerous studies that there is a
high rate of “comorbidity” between PTSD and other
disorders.
22–24
In the National Comorbidity Study,
Kessler and his colleagues
25
found that approxi-
mately 84% of their sample had another disorder
at some point in life. Individuals with PTSD were
found to be eight times more likely to have had
three or more additional disorders than individuals
who were not diagnosed with PTSD. The disorders
most consistently found to co-occur with PTSD
are: major depression, other anxiety disorders, sub-
stance abuse, somatization disorder, and a variety
of Axis II disorders.
25–28
In fact, in a consensus state-
ment, leaders in the field noted that the “pure form” of
PTSD is actually unrepresentative of the typical clini-
cal presentation of PTSD.
29
They described PTSD as
being associated with an “increased risk for secondary .
. . disorders.”
(p. 63)
While many have conceptualized this
as “comorbidity,” a number of clinicians and
researcheers have begun to reconsider what such co-
occurrence of disorders indicates about the diagnosis
of PTSD. In response to such issues, Herman and van
der Kolk
30
and, independently, Pelcovitz and col-
leagues,
21
delineated a syndrome, based on symptoms
associated with PTSD, for further study in the DSM-
IV. This syndrome was called “Disorders of Extreme
Stress” in the field trial for PTSD,
24
and later also
called “Complex PTSD” by Herman.
13
In 1992, the
World Health Organization
31
described the “lasting
personality changes following catastrophic stress,”
which went well beyond the classic PTSD criteria and
research has supported these theoretical conceptualiza-
tions. In the DSM-IV Field Trial, van der Kolk and
his colleagues
32
reported that PTSD, dissociation,
somatization, and affect dysregulation were all
highly interrelated. They further found that many
individuals with PTSD also consistently displayed a
number of other symptoms not captured in the PTSD
diagnostic criteria. Subsequent research has provided
strong empirical support for these initial observa-
tions.
33–35
The findings of the DSM-IV Field Trial for PTS D
suggest that trauma has its most profound impact
when its onset occurs during early childhood or
adolescence and becomes less perva s i vely damaging
with later onset.
3 2 , 3 6
In fact, almost half of the trauma-
t i zed sample in this re s e a rch had experienced Cr i t e r i o n
A traumatic stressors before age 11; individuals in this
s u b g r oup we re most likely to meet diagnostic criteria
for DESNOS. The high rates of current DESNOS in
these individuals provided compelling evidence for the
enduring impact of exposure to trauma during child-
hood. The DSM-IV Field Trial for PTS D
3 2 , 3 3
also lent
s u p p o rt to the notion that trauma, especially interper-
sonal trauma, can have perva s i ve effects on the totality
of personality and social development, resulting in
c h r onic affect dysregulation, aggression against self and
others, dissociative symptoms, somatization, and char-
acter pathology. These symptoms occur together in
many traumatized individuals, and rarely occur as a syn-
d rome in subjects not exposed to high-magnitude or
c h r onic stressors, which supports the notion that
DESNOS constitutes a complex post traumatic syn-
d r ome associated with chro n i c / s e ve r e interpersonal
t r a u m a t i z a t i o n .
1 3
In the National Comorbidity St u d y
carried out by Kessler and colleagues, it was found that
while approximately one fifth of all individuals diag-
nosed with PTSD did not meet the criteria for another
diagnosis, the remaining 79% met criteria for at least
one additional disord e r, and a full 44% met the criteria
for at least three other diagnoses.
2 5
For a substantial pro-
p o rtion of traumatized patients the diagnosis of PTS D
c a p t u r es only limited aspects of their psyc h o l o g i c a l
p roblems. The combination of posttraumatic symp-
toms re p resented by DESNOS and PTSD criteria,
rather than by PTSD alone, causes people to seek psy-
chiatric tre a t m e n t .
376
Volume 21 Lesson 25Directions in Psychiatry

Aspects of DESNOS
Estimates of the prevalence of histories of childhood
trauma in psychiatric populations range from 40% to
70%.
13–19
Yet trauma-related disorders, including
dissociative disorders, continue to be grossly
underdiagnosed.
19
This underrecognition can be
best understood in light of the multiplicity of
symptoms with which these patients present that
may not be readily recognized as being related to
their traumatic experiences.
AFFECT DYSREGULATION:
Individuals who meet criteria for DESNOS have diffi-
culty managing their emotional experiences. In fact, it
has been suggested that affect dysregulation may be
the core dysfunction that results from psychological
trauma.
37,38
Such individuals tend to overreact to
minor stresses, become easily overwhelmed,
appear to have “extreme” reactions to neutral or
mild stimuli, have trouble calming themselves, and
may use extreme, self-destructive measures, such as
self-injury, drug use, eating disorders, or compul-
sive sexual activity, in attempts to manage their
emotions.
39–41
They also typically have a great deal
of trouble either expressing or modulating their
anger, and numerous studies have found that these
individuals’ anger can significantly impact and inter-
fere with the course of treatment.
37,41–43
Further, such
individuals frequently exhibit suicidal preoccupa-
tion, either sexual preoccupation, or difficulty
modulating sexual impulses, and heightened risk-
taking behavior. Affect dysregulation is one of the
most problematic aspects of working with chronically
traumatized patients and should be a central focus of
treatment, as it can interfere with the therapy process
itself if not explicitly addressed.
DISTURBANCES IN ATTENTION
OR CONSCIOUSNESS:
Individuals frequently learn to cope with traumatic
experiences by dissociating, or separating these experi-
ences from their “everyday” level of consciousness.
44
In
the normal course of events, information about an
experience is a more or less coherent whole, with most
parts connected and readily accessible. In dissociation,
however, this integration of information does not
occur, to a greater or lesser degree. Individuals often
find that they cannot reconcile traumatic experiences
with their sense of who they are and how they perceive
the world. Such experiences become relegated to
separate aspects of consciousness
45
that do not
impinge on the individual’s day-to-day level of
consciousness. For example, when the totality of an
experience is too overwhelming, various elements
(e.g., visual, emotional, somatic) of the experience
may be split off from one another, and from the indi-
vidual’s own personal narrative. As van der Kolk and
colleagues
46
have discussed, these “split off” aspects
of the traumatic experience(s) are typically percep-
tual or sensory (rather than linguistic) in nature, and
are often initially experienced as inexplicable phys-
ical sensations that cannot be verbally explained or
deconstructed, as is often expected in therapy. In
addition, chronically traumatized patients often learn
to dissociate their bodily sensations and experiences, as
the body frequently becomes linked with danger and
distress in trauma. Such individuals may actually
not have a sense of what it feels like to be in their
bodies.
C h ronically traumatized individuals may have
only intermittent ability to access certain inform a-
tion, they may be ve ry “forgetful,” they may appear
to “space out” re g u l a r l y, and they may re t re a t
within themselves when confronted with painful
emotions or reminders of their traumatic experi-
ences. It is common, for example, for such individuals to
h a ve difficulty remembering what was discussed betwe e n
sessions, or to forget safety plans or coping skills. This will
be discussed in greater depth short l y. In addition,
c h r onically traumatized individuals often have amnesia
for significant portions of their lives. This can invo l ve
single experiences (e.g., graduating from college), or
whole months or even years (e.g., not re m e m b e r i n g
anything from the time period that one lived in a cer-
tain city). In treatment, this clearly complicates history
gathering and the cohesiveness of interventions, and
can be a source of distress in and of itself.
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part One: Assessment Luxenberg, Spinazzola, & van der Kolk
377

In one study, the highest levels of dissociation
occurred in individuals who had experienced mul-
tiple traumas.
47
Dissociation in its extreme form
can lead to Dissociative Identity Disorder (DID),
but it is important to note that while a substantial
number of individuals carry that diagnosis (1% of the
general population),
48
a larger number of individuals
with chronic trauma histories experience significant
amounts of some form of dissociative symptomatol-
ogy. Saxe and colleagues,
19
for example, found that
15% of 110 psychiatric inpatients exhibited signifi-
cant dissociation, while Waller and Ross
49
found that a
full 3.3% of the general population sampled displayed
what they called “pathological dissociation.” This led
Ross
48
to state that dissociative disorders “as a group
are as common as anxiety and affective disorders.”
(p. 515)
DISTURBANCES IN
SELF-PERCEPTION:
Individuals with DESNOS often develop negative
views of themselves as being helpless, ineffectual,
damaged, and undesirable to others.
50
These percep-
tions spring directly from the way young children inter-
pret the world; their preoperational thinking places them
in the center of the universe, leading them to believe that
they have “caused” their own mistreatment. At the same
time, they often have problems taking appropriate
responsibility for their actions, just as young children
do. In addition, chronically traumatized individuals
often feel that no one can understand their experience,
or they may drastically minimize their own experi-
ences as not having had a major impact on them or
being unrelated to their current difficulties. Such indi-
viduals may emphatically insist that they were at fault
for childhood molestation due to some inherent char-
acter flaw or “badness” that their abuser detected in
them, and on which they acted.
DISTURBANCES IN RELATIONSHIPS:
C h ronically traumatized patients typically have histories
m a r ked by numerous and varied dysfunctional re l a t i o n-
ships. Childhood maltreatment has consistently been
linked with difficulty trusting others, re v i c t i m i z a-
tion, and the victimization of others.
51–53
Such indi-
viduals often “shut dow n” and do not pick up danger
signs, such as their own feelings of unease, hurt, or
a n g e r, or inappropriate behavior on another’s part .
For example, overly friendly behavior in a virt u a l
stranger or new acquaintance typically will lead to a
sense of confusion and wariness in most non-trauma-
t i z ed individuals, but it may not in those who have
been chronically traumatized and have no healthy
template for interpersonal interactions. In addition, a
n o n - t r a u m a t i zed individual who finds him- or herself
being treated in manner which makes them uncomfort-
able (e.g., being called names by his or her partner) will
typically insist that such behavior stop and will cease to
interact with the person invo l v ed if it continues. T h i s ,
h o we ve r, is frequently not the case with chronically trau-
m a t i z ed individuals, who often continue to pursue inter-
action with those who embarrass, confuse and upset
them. Fu rt h e r, traumatized individuals often are not able
to see initial, “m i n o r,” incidents as harbingers of what is
to come, as happens in the case of a woman who is
s e ve r ely beaten by her boyfriend after experiencing mul-
tiple incidents of being slapped and pushed. In addition,
c h r onically traumatized individuals are often unable to
use bodily signals (such as accelerated heart rate, discom-
f o r t, changes in breathing, physical urges to flee, or gas-
t r ointentional distress) as guides for action, only feel
a l i v e when agitated or in conflict, and often accept re v i c -
timization as a matter of course in relationships. In the
latter case, they may actually be aware of danger signals,
but feel powerless to act on them, or be too frightened of
the consequences to do so. They may anticipate that
their partners will leave or hurt them, and they may have
difficulty developing support i v e social re l a t i o n s h i p s ,
g i v en their mistrust of others. In addition, their limited
sense of self, and the problems they have experiencing
their separateness from others, reduce their ability to
t r uly engage in mature mutuality and sharing. T h e
p r opensity of chronically traumatized individuals to dis-
sociate from their own bodies also seve rely constricts
their capacity to enter into relationships, as they stru g g l e
to know even themselves. Tr a u m a’s profound impact on
the body is a ve ry important topic, please see Be yond the
Talking Cu re by Dr. van der Kolk for more informa-
t i o n .
5 4
378
Volume 21 Lesson 25Directions in Psychiatry

Relationship building in therapy with such individ-
uals can be a slow and arduous process, and therapists
typically must wrestle with and adjust for their
patients’ feelings of being traumatized and victimized
by the therapy relationship. Further, it is typical
for such patients to reenact their interpersonal
traumas in therapy and elsewhere.
33,55
For example, a
woman who has a history of childhood sexual assault
may frequently pick intimate partners who are domi-
neering and who do not take her needs or desires into
account. These relationships will cause the individual
to feel out of control and trespassed against, as she did
when she was being molested as a child. This may or
may not be explicitly reenacted in the realm of sexual-
ity. Alternatively, individuals may victimize others in
ways that replicate their own traumas, either literally
or emotionally.
SOMATIZATION:
Many chronically traumatized patients suffer fro m
persistent physical complaints that often defy med-
ical explanation or interve n t i o n . Be f o re examining
this, howe ve r, it is necessary to further explore the
effects of trauma on the body. T h e re is ample evidence
that repeated traumatic experiences have an impact
on a biological level. Re s e a rc h
3 8 , 5 6 – 5 8
has demonstrated
that the stress response entails the release of endoge-
nous, stre s s - re s p o n s i v e hormones. These hormones pre-
p a r e the body to mobilize re s o u r ces to respond to
t h r eatening situations quickly and effective l y. Chro n i c
e x p o s u r e to stress results in the effectiveness of this sys-
tem being significantly compro m i s e d .
59
In addition to
n e u ro h o r monal dysregulation, exposure to trauma
has also been found to significantly impact the lim-
bic system and its crucial role in evaluating the emo-
tional significance of incoming stimuli and facilitat-
ing the encoding of semantic memory. Trauma has
n e u roanatomical impacts as well, with hippocampal
volume having been found to be smaller in traumatize d
versus nontraumatized individuals;
6 0
and the negative
impact on information processing is we l l - k n ow n .
6 1
C h r onically traumatized individuals have difficulties
adjusting their level of physiological aro u s a l ,
59
s u g g e s t-
ing that the nervous system has become ove r re s p o n s i ve
to previously innocuous stimuli. Tr a u m a t i zed individu-
als have ove r a c t i ve sympathetic and parasympathetic
n e rvous systems.
6 2
One obvious example of this is the
exaggerated startle response that is characteristic of
P TSD. Tr a u m a t i zed individuals respond to va r i o u s
stimuli at a lower threshold than do nontraumatize d
i n d i v i d u a l s .
5 8
The ove r p roduction of catecholamines,
such as norepinephrine, is just one of the many neuro-
hormonal reactions invo l ved in this unmodulated
response to minor stre s s e s .
62
This ove r p roduction re s u l t s
in general feelings of anxiety, and signs of hyperaro u s a l ,
such as oversensitivity to stimuli, and difficulty sleep-
ing. The underproduction of serotonin, another neuro-
hormone that mediates
6 3 – 6 6
the behavioral inhibition
system, leads to increased reactivity and “e m e r g e n c y”
responses. Overall, loss of neuromodulation often trans-
lates into heightened irritability, impulsivity, and aggre s-
s i v eness for traumatized individuals.
6 4 , 6 7
Fu rt h e r, it has
been well documented that t r a u m a t i zed individuals
u n d e r p roduce cort i s o l ,
6 8
which, according to Ye h u d a
and colleagues
6 9
s e r ves as an “a n t i - s t re s s” hormone by
signaling that other stre s s - related responses should be
s u p p ressed. In addition to reduced glucocorticoid pro-
duction (of which cortisol is an example), chronic stre s s
or traumatization also leads to e l e vated rates of
endogenous opioid pro d u c t i o n ,
70,71
resulting in anal-
gesia in response to reminders of traumatic eve n t s .
Wilson and colleagues
7 2
h a v e found immune system
dysfunction in women with histories of chronic sex-
ual abuse in childhood. Out of ten subjects, all had
i n c reased lymphocyte immune activation, as compare d
to matched controls. Although this phenomenon is not
yet fully understood, it is believed that chronic trauma
may “re s e t” the body’s physiologic functioning, in the
s e rvice of being pre p a r ed for the next dangerous eve n t ,
which may come to be anticipated on a physiological
l e v el. Over time, this may have negative consequences
for basic functioning.
Many chronically traumatized patients exhibit
multiple somatic difficulties. Felitti and colleagues
39
found that as the number of traumas increased, physi-
cal health decreased precipitously. Traumatized indi-
viduals have documented increases in difficulties in
their digestive, cardiopulmonary, and urogenital
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part One: Assessment Luxenberg, Spinazzola, & van der Kolk
379

systems.
73
Typical complaints include Irritable
Bowel Syndrome, chronic pelvic pain,
74
headaches,
and “acid” stomach. Chronically traumatized indi-
viduals often respond poorly to conventional med-
ical treatment, and experience more severe or persis-
tent symptoms than would be expected in
conjunction with an existing disorder or disease. They
also frequently report unusual symptoms for which
there can be found no obvious physical cause, such as
temporary blindness, tingling in extremities, or
seizure-like activity. In a large-scale survey of almost
10,000 adults,
39
exposure to adverse childhood experi-
ences (including numerous traumatic events) was
found to dramatically increase health risk factors for
several of the leading causes of death in adults, includ-
ing heart disease, stroke, diabetes, skeletal fractures,
and cancer. For those individuals who had three or
more adverse childhood events, they were typically
twice as likely as their peers without any adverse events
to develop the above-mentioned diseases and medical
problems. In the case of chronic bronchitis or emphy-
sema, those individuals with three or more adverse
events were a stunning four times as likely the disease
when compared to their peers who had not suffered
any adverse events. As van der Kolk
38
has pointed
out, having lost the ability to put words to their
traumatic experiences, physical symptoms may
provide some chronically traumatized individuals
with a symbolic way of communicating their emo-
tional pain. In fact, such individuals may experience
no psychological distress at all, but simply report trou-
bling physical symptoms.
74
DISTURBANCES IN
MEANING SYSTEMS:
Many chronically traumatized individuals often
view the world through a dark lens. They fre-
quently report that they no longer believe that life
makes sense or has a purpose.
50
They may question
the religious or ethical belief structures with which
they were raised, and see any spiritual being or force as
being actively malevolent or insensitive to human suf-
fering. They may adopt an “every person is out for
themselves” attitude or a fatalistic approach to life,
anticipating that, ultimately, they will not be able to
make positive changes in their life. This is a profound,
persistent, and physical sense of learned helplessness
that dramatically affects the capacity to formulate
options, make choices, act on one’s own behalf, or
implement changes in one’s life. Clearly, such condi-
tions can undermine the effectiveness of therapy and
must be addressed.
Psychometric
Assessment of DESNOS
To date, two clinical instruments have been developed
and validated for the purpose of comprehensive assess-
ment of DESNOS in clinical practice and research.
These are the Structured Interview of Disorders of
Extreme Stress (SIDES)
21
and the Self-Report Inventory
for Disorders of Extreme Stress (SIDES-SR).
75
In addi-
tion to these instruments, a handful of other psycho-
metric measures, while not specifically developed for
this purpose, have been found in our clinical work and
research to be useful in assessing particular compo-
nents of the DESNOS construct. These include the
Traumatic Antecedents Questionnaire (TAQ),
82
the Dis-
sociative Experiences Scale (DES),
83
the Inventory of
Altered Self-Capacities (IASC),
84
and a careful review of
health service utilization.
STRUCTURED INTERVIEW
OF DISORDERS OF EXTREME
STRESS (SIDES):
The SIDES was developed during the DSM-IV Field
Trial for PTSD as a companion to existing clinical
interview-based rating scales for PTSD and other Axis
I disorders such as the Clinician Administered PTSD
Scale (CAPS)
76
and the Structured Clinical Interview for
DSM-IV Disorders (SCID-IV).
77
The SIDES is a 45-
item structured clinical interview that consists of six
subscales corresponding to the six DESNOS symptom
clusters. The SIDES was designed to measure current
and lifetime presence of DESNOS, as well as current
symptom severity (past month). Item descriptors con-
tain concrete behavioral anchors to better facilitate
clinician ratings of symptom presence and severity.
380
Volume 21 Lesson 25Directions in Psychiatry

The SIDES is the only instrument that has been
validated for the purpose of diagnostic assessment
of DESNOS. Research on the psychometric proper-
ties of the SIDES has supported its reliability as a diag-
nostic tool
21
and as a continuous measure of symptom
severity for the overall diagnosis (J. Spinazzola, Ph.D.,
M.E. Blaustein, Ph.D., B.A. van der Kolk, unpub-
lished data, 2001). While to date this research has
focused on the utility of the SIDES as a baseline mea-
sure of DESNOS diagnosis and symptom severity,
additional research is currently underway to evaluate
its utility as a measure of treatment outcome.
Additional research using this instrument has
provided sound preliminary empirical evidence for
the validity of the DESNOS construct.
78–80
For
example, in a study examining the affect dysregula-
tion, dissociation, self-perception and somatization
subscales of the SIDES, Zlotnick and Pearlstein found
strong support for the convergent and discriminant
validity of these subscales by comparing them to other
established measures of similar and divergent con-
structs.
78
Furthermore, in a recent study comparing a
clinical research sample of patients diagnosed with
PTSD alone versus patients with diagnoses of
PTSD and DESNOS as measured by the SIDES,
the latter group were not only found to meet crite-
ria for a greater number of comorbid Axis I and
Axis II DSM-IV diagnoses, but were also found to
exhibit a pattern of comorbid diagnoses reflective
of four of the same underlying deficit areas pur-
ported to characterize the DESNOS construct: reg-
ulation of affect, self-perception, somatic function,
and relationships.
80
A comprehensive training manual for clinicians and
researchers containing detailed information pertaining to
the administration, scoring, interpretation, and norms of
the SIDES, as well as the SIDES-SR is currently in
preparation. A preliminary version of this manual and
information regarding SIDES training workshops is
available through the Trauma Center website
(www.traumacenter.org) or by contacting the second
author of this lesson (spinazzola@traumacenter.org).
81
SELF-REPORT INVENTORY
FOR DISORDERS OF EXTREME
STRESS (SIDES-SR):
The SIDES-SR is a 45-item self-report measure
that has recently been developed by van der Kolk
75
for measurement of: (a) baseline severity of
DESNOS; (b) baseline symptom severity of each of
the six individual symptom clusters; and (c) symp-
tom change over time. As such, the SIDES-SR is the
only instrument to date that has been developed to
provide a continuous measure of current severity
scores for each of the six DESNOS symptom clusters.
A printout of a SIDES-SR scoring sheet, illustrating
life symptom endorsement and current symptom
severity for a typical patient with DESNOS is pro-
vided in the Appendix A. A recent psychometric study
on the SIDES-SR has generally supported its use for
this purpose (J. Spinazzola, Ph.D., M.E. Blaustein,
Ph.D., B.A. van der Kolk, unpublished data, 2001).
In this study, the authors found acceptable to high
rates of internal consistency for the full scale (Cron-
bach (a = .93) and five subscales (a = .74 to .82) of the
SIDES-SR, indicating that these scales may be reliably
interpreted in a continuous fashion. Lower observed
levels of internal consistency on the Somatization sub-
scale (a = .68) suggest that scores on this scale should
be interpreted with caution. Additional empirical
research evaluating the utility of the SIDES-SR in
measuring state-dependent variability in DESNOS
severity over time, in particular at multiple time points
during the treatment course, is currently underway.
Like the SIDES, the SIDES-SR consists of 45 items
that correspond to symptoms delineated in the
DESNOS diagnosis. Patients are asked to endorse the
lifetime and current presence or absence of each symp-
tom, as well as to rank the current severity of endorsed
symptoms. Each item’s descriptors contain concrete
behavioral anchors to better facilitate patient ratings.
SIDES-SR scale items and behavioral anchors were
developed by content area experts to convey
DESNOS symptoms in a manner readily understand-
able to patients. Item and anchor revision and modifi-
cation were based on scale reliability estimates (e.g.,
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part One: Assessment Luxenberg, Spinazzola, & van der Kolk
381

subscale alphas, item-scale correlations), as well as
patient feedback (J. Spinazzola, Ph.D., M.E.
Blaustein, Ph.D., B.A. van der Kolk, unpublished
data, 2001).
TRAUMATIC ANTECEDENTS
QUESTIONNAIRE (TAQ):
Numerous self-report measures and clinician-inter-
view–based inventories have been developed to assess
lifetime exposure to a range of traumatic events (for a
review, see Wilson and Keane).
85
Of these, we have
found the TAQ.
82
particularly useful because of its
focus on the occurrence of traumatic exposure within
a developmental framework. The current version of
the TAQ is a 42-item self-report measure developed by
van der Kolk (B.A. van der Kolk, M.D., unpublished
instrument, 1997) to be used in conjunction with the
SIDES to gather information about the frequency and
severity of exposure to traumatic as well as adaptive
experiences within and across four developmental
periods: early childhood (birth to age 6); middle child-
hood/latency (age 7 to 12); adolescence (age 13 to 18);
and adulthood. The following eleven domains of expe-
rience are assessed using the TAQ: (1) competence, (2)
safety, (3) neglect, (4) separation, (5) family secrets,
(6) emotional abuse, (7) physical abuse, (8) sexual
abuse, (9) witnessing trauma, (10) other traumas (e.g.,
natural disaster, serious accident, traumatic loss of
intimates), and (11) exposure to drugs and alcohol.
The first two domains represent experiences associated
with adaptive functioning and protection against the
development of psychopathology, with higher scores
on these scales reflecting superior adjustment. The lat-
ter eight domains assess exposure to traumatic or
adverse experiences, with higher scores reflective of
more frequent and or severe traumatic exposure. A
printout of a TAQ scoring sheet, illustrating extent of
trauma exposure by type and developmental period
for a typical patient with DESNOS, is provided in
Appendix B.
Routine use of the TAQ as a component of the
intake evaluation for patients at our center has sug-
gested the following key indicators of poor progno-
sis: (a) low scores on early childhood measures of
competence and/or safety; and (b) presence of mul-
tiple forms of trauma during early childhood.
Analysis of the psychometric properties of the TAQ is
currently underway, and preliminary research utilizing
this instrument has been promising. In a recent study
examining data from 70 consecutive adult admissions
to our center
75
scores on the TAQ were consistently
found to be significantly related to symptoms of
DESNOS, and to a lesser extent with an adapted ver-
sion of the Modified PTSD Symptom Scale.
86
Specifically, preliminary correlational analyses indi-
cated a significant association between trauma type
and outcome, with Sexual Abuse, Physical Abuse,
Emotional Abuse, and Other Traumas as the
domains most associated with symptoms of
DESNOS, and Other Traumas as most strongly
associated with PTSD. Subsequent regression analy-
ses, however, revealed that the developmental period
during which traumatic exposure occurred played a
more critical role in adult outcomes related to
DESNOS than did the specific type(s) of trauma
experienced.
75
In particular, consistent with our clini-
cal observations, cumulative trauma during early
childhood and adolescence, respectively, emerged as
the two most powerful predictors of current DESNOS
severity in our adult sample.
DISSOCIATIVE EXPERIENCES SCALE:
The DES is a 28-item self-report instrument that
instructs patients to rate the percentage of time
they engage in a range of normative and pathologi-
cal dissociative experiences.
83
The DES is the most
widely used and well-validated measure of dissocia-
tion, and research employing this instrument has pro-
vided normative data for various clinical and commu-
nity samples, including patients with PTSD,
Dissociative Disorder-Not Otherwise Specified, and
Dissociative Identity Disorder.
87
Mean DES scores for
DESNOS patients have yet to be established. Prelimi-
nary findings from use of the DES with DESNOS
patients in our clinic and research center, however, sug-
gest that the mean DES score for DESNOS patients is
significantly higher than for patients with PTSD in the
absence of DESNOS. In turn, DES levels for this sample
382
Volume 21 Lesson 25Directions in Psychiatry

of DESNOS patients were observed to be lower than
those that have been typically reported in the literature
for patients with Dissociative Disorders.
88
Inclusion of
this measure in a comprehensive assessment battery
for DESNOS is recommended to facilitate treatment
planning by identifying the extent and specific types
of dissociative phenomena experienced by these
patients. This is particularly relevant given consistent
clinical indications of lower tolerance for trauma-pro-
cessing interventions in trauma patients with more
severe dissociative problems.
INVENTORY OF ALTERED
SELF-CAPACITIES:
The IASC is a 63-item self-report measure that yields
seven scale scores reflective of difficulties in the areas
of affect control, relatedness, and identity.
84
Initial
validity and reliability estimates of the IASC are
impressive (e.g., Cronbach alphas range from .79 to
.83).
84
Although the specific utility of the IASC in
assessing baseline severity of DESNOS symptoms or
in monitoring symptom change during the course of
treatment has yet to be determined, three of the IASC
scales appear to be particularly applicable to this pur-
pose, including two indices of affect control (Affect
Dysregulation and Tension Reduction Activities) and
one index of relatedness (Interpersonal Conflicts).
Additional IASC scales assessing dimensions of iden-
tity and interpersonal disturbance, while more akin to
dimensions of disturbance tapped by the Borderline
Personality Disorder (BPD) diagnosis (e.g., Idealiza-
tion-Disillusionment, Abandonment Concerns, Iden-
tity Impairments), may also prove to be relevant to the
evaluation of functioning deficits in patients with
DESNOS.
HEALTH SERVICE
UTILIZATION REVIEW:
Optimal evaluation and tracking of medically
identifiable as well as psychogenic somatic com-
plaints in DESNOS patients require careful atten-
tion to general and mental health service utiliza-
tion over time. This can be accomplished through a
variety of means, including review of patient medical
records, thorough baseline and subsequent clinical
interviews, and utilization of standardized instruments
specifically designed for these purposes. Advantages of
incorporating the latter method include facility and
uniformity of systematic data collection across
patients. Toward this purpose we recommend that
such forms gather data about the following types of
medical and psychiatric health services the patient
has used during specified time periods: (1) fre-
quency of telephone and in-person crisis support;
(2) frequency of medical and psychiatric outpatient
care; (3) frequency of medical and psychiatric inpa-
tient care; (4) frequency of emergency room use;
and (5) frequency and nature of changes in pre-
scription of psychotropic medication.
Differential Diagnosis
A word about diagnosis is in order at this point. The
current diagnostic system is embodied in the Diagnos-
tic and Statistical Manual of Mental Disorders, Fourth
Edition (DSM-IV).
20
This nosological system endeav-
ors to guide both treatment and research on mental ill-
ness, most recently through a reliance on incremental
advances in empirical research intended to clarify, con-
firm, or revise clinically and theoretically derived con-
structs of psychopathology that were initiated in the
first edition of this manual. Like other non-etiologi-
cally based classification systems, however, the DSM-
IV ultimately must succumb to the compromise posi-
tion of drawing somewhat arbitrary distinctions
between clinical phenomena in the service of con-
structing a widely used, if not universal, nosological
system. The benefits of this system are efficiency and
the development of a common language for mental
health practitioners, clinical researchers, policymakers,
and the patients themselves. One cost of such a system
is that practitioners can become overly reliant on arti-
ficial distinctions between disorders, and thereby fail
to account for symptomatology that is not readily sub-
sumed under existing diagnostic formulations. The
challenge thus becomes to work within the existing
system to characterize as precisely as possible what we
know about the statement of psychopathology in vari-
ous clinical populations.
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part One: Assessment Luxenberg, Spinazzola, & van der Kolk
383

384
Volume 21 Lesson 25Directions in Psychiatry
This issue becomes particularly salient when evalu-
ating the presence of DESNOS in patients with histo-
ries of chronic traumatization. In such situations, the
issue of differential diagnosis frequently emerges. This
is not surprising, given both the high incidence of
comorbid disorders in trauma patients as well as the
substantial overlap that has been observed between
symptom clusters of DESNOS and those of other Axis
I and II disorders common to this population, such as
PTSD and BPD. Presenting symptoms of DESNOS
are often overlooked or misdiagnosed as atypical
symptom formations of established DSM-IV diag-
noses because of the nascent awareness of the
DESNOS construct. Alternately, patients are assigned
multiple DSM-IV diagnoses (e.g., PTSD + BPD +
Bipolar II Disorder) in an attempt to account for
symptom presentations that in fact can best be under-
stood by incorporation of the associated features of
PTSD or DESNOS. The presence of DESNOS is
often overlooked entirely in the evaluation and treat-
ment of patients presenting with severe mental illness,
particularly when these patients are encountered in
inpatient settings, and despite the accumulation of a
significant body of research in the past decade that
substantiates the high prevalence of histories of
chronic traumatization in these populations (e.g.,
Darves-Bornoz and colleagues,
88
Mueser and col-
leagues).
89
Not uncommonly, patients have arrived at
our center with histories of treatment-refractory con-
ditions that have been defined by some ill-fitting, con-
ventional diagnosis (e.g., Bipolar II Disorder) made in
an effort to account for chronic and severe affect dys-
regulation in the absence of full-blown manic states.
In recognition of these challenges to the differential
diagnosis of DESNOS, we will briefly address distinc-
tions between DESNOS and simple PTSD and BPD,
two of the disorders for which it is most frequently
confused. At the same time, it should be noted that
this potential for misdiagnosis is by no means mutu-
ally exclusive from the potential for the presence of
comorbid conditions of DESNOS and PTSD and/or
BPD. Along these lines, empirical data from the
DSM-IV Field Trial as well as from our center
24,32,80
have firmly established the common co-occurrence of
DESNOS, PTSD, and BPD in patients with histories
of chronic traumatization.
DESNOS VERSUS PTSD:
As described above, data from the DSM-IV Field Trial
revealed the diagnosis of DESNOS to be more com-
mon in individuals exposed to interpersonal trauma of
early onset and of lasting duration.
32
Although initially
conceptualized as a constellation of symptoms fre-
quently associated with the PTSD diagnosis, subse-
quent research
90
has confirmed that the presence of
PTSD is not in fact a necessary precondition for
DESNOS. A complete understanding of the absence
of current PTSD diagnoses in some DESNOS
patients with histories of chronic traumatization will
require further empirical research. Thus far, our
extensive clinical work with this population sug-
gests that this diagnostic profile may be a byprod-
uct of two factors common in this subpopulation
of trauma patients: (a) severe avoidance and sup-
pression of trauma-related memories (often facili-
tated through self-medication through chronic sub-
stance dependence and abuse) with associated
affective numbing and constriction (PTSD Crite-
rion C); and (b) over-reliance on dissociation as a
coping mechanism and defense against intolerable
affect. In these patients, avoidance, numbing, and
dissociative symptoms may function over time to
mask the overt intrusive symptomatology (PTSD
Criterion B) required to meet full criteria for the
PTSD diagnosis. Likewise, for trauma patients
with severe mental illness, traumatic intrusions
may become overshadowed by, or less discernibly
embedded within, more severe manifestations of
psychopathology, including paranoid ideation,
persecutory delusions, and reports of perceptual
disturbance (i.e., traumatic flashbacks that are over-
looked because they are experienced within the con-
text of otherwise bizarre auditory or visual hallucina-
tions). In the course of successfully treatment with this
subset of DESNOS patients (see next lesson on
DESNOS treatment), increased capacity to access and
express formerly intolerable affect states associated
with the trauma may actually lead to the reemergence
of intrusive PTSD symptomatology. Assuming ade-
quate affective stabilization has been achieved and
internal and environmental coping resources estab-
lished during the first phase of trauma treatment,
desensitization of the traumatic memories associated

Complex Trauma and Disorders of Extreme Stress (DESNOS), Part One: Assessment Luxenberg, Spinazzola, & van der Kolk
385
with these emerging intrusive symptoms can then be
addressed as a formal component of treatment (see
next lesson on DESNOS treatment).
DESNOS VERSUS BPD:
The distinction between DESNOS and BPD provides
perhaps the most challenging differential diagnosis to
the clinician unversed in psychological adaptations to
chronic trauma, especially in view of the potential for
diagnostic overlap or dual-diagnosis. Nevertheless, in
our clinical work we have frequently observed that
many patients who have been historically conceptual-
ized as “borderline” are, upon more thorough evalua-
tion, better characterized by the DESNOS frame-
work. In numerous instances, we have observed that
such patients are not only understood through differ-
ent diagnostic and conceptual frameworks depending
on the clinical orientation of their treatment site, but
actually present with varying symptom profiles based
on the extent to which their trauma histories have
been (a) identified by their treating clinicians and
incorporated into clinical case formulations, (b)
acknowledged as relevant factors in the etiology of
psychopathology and current symptom presentations,
and (c) addressed as significant targets in treatment.
Notably, we have found that the thoughtful inclu-
sion of trauma history in the case conceptualiza-
tion and treatment planning with these patients
often contributes to significant changes in their
symptom presentations. Specifically, trademark
personality features of the BPD patient such as
hostility, emotional manipulation, and deception
come to be replaced with more genuine feelings of
sadness, loss, and traumatic grief. Accordingly, shifts
in the clinician’s formulation of presenting problems
as well as in the patient’s developmental adaptation to
his or her experience of childhood trauma can, at
times, influence the subsequent symptom expression
and diagnostic classification of a particular patient as
DESNOS versus BPD.
Empirical re s e a rch has established that the BPD
and DESNOS diagnoses in general re p resent ove r-
lapping but distinct symptom pro f i l e s .
32,80
On the
s u rface, these disorders may appear to be quite similar,
as both relate to aspects of four of the six domains of
s e l f - re g u l a t o ry deficit captured by the DESNOS con-
s t ruct (i.e., affect, attention/consciousness, self-perc e p-
tion, and relationships). Se veral important distinctions
exist, howe ve r, between DESNOS and the classic BPD
c o n s t ruct, including notable differences in the re l a t i v e
i m p o rtance and nature of disruptions in these four
domains of self-regulation. For instance, w h e re a s
c h ronic affect dysregulation is the hallmark feature
of DESNOS, this symptom is secondary to distur-
bances in identity and relationships with others in
B P D .
2 0
In essence, BPD re p resents a disorder of
attachment, while DESNOS is considered by most
leading clinicians and re s e a rchers in the field to be
better understood as a disorder of self-regulation.
Affect Regulation
Affect in DESNOS patients is more chronically and
persistently emphasized in the direction of a down-
ward dysregulation than is the case in BPD patients,
who in contrast exhibit greater range in their capacity
for transient upward emotional spikes. The contin-
uum of mood in patients with DESNOS typically
ranges from a dysthymic/anxious baseline to profound
states of rage, terror, or hopelessness. The brief periods
of excitement, positive anticipation, and euphoria
observed in BPD patient—often associated with tran-
sient idealizations of new intimate others or treatment
providers—are less commonly observed to be compo-
nents of a true DESNOS symptom presentation. In
fact, a cardinal but under-recognized feature of
DESNOS patients is their profound deficit in the
capacity to sustain positive emotional states, expe-
rience pleasure, and become absorbed in positive
and present-focused states of awareness.
Relationships
The nature of interpersonal dysfunction characterized
by the DESNOS construct varies from that of the
BPD diagnosis as articulated in the DSM-IV. The
BPD patient’s fundamental interpersonal orientation
is an active one: an approach-based stance character-
ized by the duality of desire and disillusionment. BPD
is often characterized by the oscillation between
intense longing and search for idealized (and there-
fore unrealistic and ultimately untenable) relation-

386
Volume 21 Lesson 25Directions in Psychiatry
ships, and the equally intense devaluation and ulti-
mate sabotage of these relationships. Conversely,
when an intimate other threatens to pull out of what
had been perceived by the patient to be an unsatisfy-
ing relationship, the BDP patient can become over-
come with a resurgence of desire to maintain this rela-
tionship occasioned by desperate fear of abandonment
and rejection by the other. In other instances, the
BPD patient will concoct, and become temporarily
consumed by vaguely articulated fantasies of a “per-
fect” future with a new caregiver or potential lover,
only later to feel the sting of disappointment at the
other’s inability to fill the profound emptiness at the
core of his or her own being. As has been well estab-
lished and the subject of much of the clinical literature
on BPD, these patterns typically manifest themselves
early in these patients’ transference responses to new
treatment providers.
In contrast, the basic interpersonal orientation of
the DESNOS patient is passive in nature, charac-
terized by a duality of avoidance and revictimiza-
tion. For example, these patients often engage in pro-
longed periods of self-inflicted social isolation and
avoidance of intimate contact. At other times, how-
ever, they report abruptly discovering themselves to be
in the midst of an intense emotional relationship that
feels unsafe or out of control. In fact, when DESNOS
patients do enter intimate relationships, it is often as a
result of being the target of victimizing others who
have been drawn to these patients’ emotional vulnera-
bility, underdeveloped capacity to identify danger
cues, and tolerance for violence and boundary viola-
tions as an inherent component of intimate relation-
ships. DESNOS patients are often observed, to the
chagrin of their therapists, to reenact their interper-
sonal traumas, repeatedly finding themselves helplessly
playing out the role of victim, or, alternately, com-
pelled to victimize others in ways similar to those
experienced in their own history of childhood trauma-
tization.
DESNOS patients not only tend to fear and believe
themselves to be unworthy of meaningful relation-
ships with others; they are generally incapable of imag-
ining a future for themselves in which they can love
and be loved in a relationship that is free of abuse.
Given this pessimism about the potential for positive
interpersonal connection and general distrust of oth-
ers, DESNOS patients are not surprisingly somewhat
less likely than patients with BPD to engage in bound-
ary violations and intrusiveness with their therapists at
the outset of treatment. In contrast, they often present
as apprehensive, guarded, and at times hostile toward
new treatment providers. The establishment of safety
and trust is perhaps the most important component of
the initial phase of treatment with these patients.
Dissociation
Dissociative symptom presentations differ notably
in patients with these two disorders. Dissociative
symptoms associated with BPD are characterized
by transient responses to stress, the occurrence of
which is not required to meet diagnostic criteria.
Clinical research on dissociative symptomatology as
measured by the DES has consistently found that
patients with BPD report lower levels of dissociative
symptoms than patients with PTSD.
88
In contrast, the
presence of significant dissociative symptomatol-
ogy is an essential and required component of the
DESNOS diagnosis. These symptoms may take a
variety of forms ranging from episodic experiences
of derealization to lasting psychogenic amnesia for
portions of one’s traumatic experiences, to the pres-
ence of Dissociative Identity Disorder.
Self-Perception
The following distinctions can be made regarding the
type and extent of disturbances in self-perception
observed in these two disorders. Whereas the pri-
mary feature of disturbance in self-perception for
patients with BPD involves a fundamental confu-
sion about self, the DESNOS patient experiences a
self that has been permanently damaged and alien-
ated from others. At the core of identity disturbance
for patients with classic BPD lays the absence of a
sense of self or ego identity, and the persistent affective
experience of emptiness associated with the void left
by the unformed self. Perhaps the key component of
the severe psychopathology of these patients is the
intolerable black hole of this void that always beckons,
making the risk for suicide a constant consideration in

Complex Trauma and Disorders of Extreme Stress (DESNOS), Part One: Assessment Luxenberg, Spinazzola, & van der Kolk
387
treatment. DESNOS patients, in contrast, although
plagued by negative affect states of guilt, shame, and
ineffectiveness associated with their experience of a
damaged self, nevertheless possess, on some funda-
mental level, a basic core sense of identity, albeit often
the problematic dual identity of victim and patient. In
fact, their desperate clinging to trauma-based identi-
ties as victim/patient is often quite pronounced, as it
becomes a source of personal meaning-making and
provides a compelling explanatory model for and
source of “proof” of their chronic experience of inter-
personal suffering and emotional pain. For such
patients, this identity formation is perhaps the greatest
obstacle to genuine treatment progress.
Obv i o u s l y, symptom presentation and tre a t m e n t
course becomes more complicated for individuals
dually diagnosed with DESNOS and BPD. A full con-
sideration of this issue is beyond the scope of the pre-
sent paper. In brief, howe ve r , it is strongly re c o m-
mended that treatment for such patients prioritizes and
begins with the targeting and stabilization of more
s e ve r e deficits in self- and affect-regulation including
t reatment interfering, suicidal and self-harming behav-
iors. Treatment approaches with these patients
should invo l ve the incorporation of modalities
specifically developed and validated for patients
with BPD within a framew o rk of trauma-focused clin-
ical formulation, psychoeducation, and patient va l i d a-
tion of emotional pain. Of the existing interve n t i o n s
for BDP, we have found Dialectical Behavior T h e r a p y
( D B T)
9 1
to be particularly applicable to the tre a t m e n t
of patients dually diagnosed with DESNOS and BPD.
Summary
DESNOS is a diagnosis that encompasses a pervasive
pattern of adjustment that may occur in response to
persistent traumatization that occurs across settings,
and frequently involves numerous types of trauma, or
trauma of long duration. Such experiences disrupt and
alter maturing biological and emotional systems, par-
ticularly when they occur during early childhood.
DESNOS has persistent biological, emotional, inter-
personal, and social components that all must be
assessed and addressed in treatment. The primary
deficits relate to: (1) the regulation of affect and
impulses; (2) attention or consciousness; (3) self-per-
ception; (4) relations with others; (5) systems of
meaning; and (6) somatization. DESNOS can be
directly assessed through the use of the SIDES and
SIDES-SR. Further, aspects of the DESNOS constel-
lation can be evaluated through the use of instruments
such as the DES and the IASC, as well as through
health services utilization review.

Appendix A
SCORING SHEET ILLUSTRATING LIFE SYMPTOM ENDORSEMENT AND
CURRENT SYMPTOM SEVERITY FOR THE TYPICAL PATIENT WITH DESNOS
Scores of 2 or above are clinically significant, and
“Current” threshold scores for items and subscales. LIFETIME CURRENT
I. Alterations in regulation of affect and impulses
(A and one of B–F required)
A. Affect Regulation Yes 2.0
B. Modulation of Anger No 0.0
C. Self-Destructive Yes 0.0
D. Suicidal Preoccupation Yes 3.0
E. Difficulty Modulating Sexual Yes 3.0
F. Excessive Risk Taking No 0.0
II. Alterations in attention or consciousness
(A or B required)
A. Amnesia Yes 2.0
B. Transient Dissociative Episodes No 0.0
and Depersonalization
III. Alterations in self-perception
(Two of A–F required)
A. Ineffectiveness Yes 2.0
B. Permanent Damage Yes 3.0
C. Guilt and Responsibility No 0.0
D. Shame Yes 0.0
E. Nobody Can Understand Yes 3.0
F. Minimizing No 0.0
IV. Alterations in relationships with others
A. Inability to Trust Yes 2.3
B. Revictimization Yes 3.0
C. Victimizing Others No 0.0
V. Somatization
(Two of A–E required)
A. Digestive System Yes 2.0
B. Chronic Pain Yes 2.0
C. Cardiopulmonary Symptoms No 0.0
D. Conversion Symptoms No 0.0
E. Sexual Symptoms Yes 0.0
VI. Alterations in systems of meaning
(A or B required)
A. Despair and Hopelessness Yes 2.5
B. Loss of Previously Sustaining Beliefs Yes 0.0
388
Volume 21 Lesson 25Directions in Psychiatry
YES 1.3
YES 0.8
YES 1.8
YES 1.3
YES 1.0
YES 1.3

Complex Trauma and Disorders of Extreme Stress (DESNOS), Part One: Assessment Luxenberg, Spinazzola, & van der Kolk
389
Appendix B
INTAKE SUMMARY SCORES:TRAUMATIC
ANTECEDENTS QUESTIONNAIRE (TAQ)
SCALE CHILDHOOD ADUL THOOD TOTAL
Young Child School Age Adolescent
(0–6) (7–12) (13–18)
Higher Scores are Better:
COMPETENCE 2.0 3.0 2.5 2.0 9.5
SAFETY 0.0 0.0 0.0 2.0 2.0
Higher Scores Indicate Greater Exposure:
NEGLECT 2.7 2.7 2.0 2.0 9.3
SEPARATION 3.0 3.0 3.0 3.0 12.0
SECRETS 3.0 3.0 0.0 0.0 6.0
EMOTIONAL ABUSE 3.0 2.5 2.3 0.0 7.8
PHYSICAL ABUSE 0.0 0.0 0.0 2.5 2.5
SEXUAL ABUSE 2.0 2.3 2.0 0.0 6.3
WITNESSING 0.0 2.0 2.0 0.0 4.0
OTHER TRAUMAS 0.0 2.0 2.3 2.0 6.3
ALCOHOL & DRUGS 2.0 2.0 2.0 3.0 9.0
Explanation of Scores:
Scores are calculated with a threshold-based system.
No raw scores of 0 or 1 for individual TAQ items, i.e., endorsements of (1) “Not at all” or “Never” and (2)
“Rarely” or “A little bit” are included in the calculatin of scores for age periods.
Only raw scores of 2 or 3, endorsements of (2) “Occassionally” or “Moderately” and (3) “Often” or “Very
Much,” are averaged to generate age-period scores.
TOTAL scores are sums of age-period scores for that scale.

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Volume 21 Lesson 25Directions in Psychiatry

Questions Based On This Lesson
For more information about Hatherleigh, look up our website at www.hatherleigh.com, or give us a call at 800-367-2550.
To earn CME credits, answer the following questions on your quiz response form.
7 3 . Which one of the following statements is n o t
c o r re c t ?
A. The majority of people experience at least one
traumatic event during their lifetimes, and up
to 25% of them will ultimately develop
PTSD.
B. The clinical presentations of patients with
PTSD who have survived car accidents or
natural disasters do not differ materially from
those who have experienced abuse at the
hands of caregivers.
C. Individuals with PTSD have been found to
be eight times more likely to have three or
more additional disorders than those without
PTSD, most commonly major depression,
anxiety disorder, substance abuse, and somati-
zation disorder.
D. The DSM-IV diagnosis, Disorders of
Extreme Stress, Not Otherwise Specified
(DESNOS), or Complex PTSD, is linked
with histories of interpersonal victimization,
multiple traumatic events, and traumatic
exposure of extended duration.
74. The diagnosis of DESNOS involves distur-
bances in all of the following areas of function-
ing, except:
A. Regulation of affect (e.g., troubling expressing
or modulating anger and overreacting to
minor stresses).
B. Attention or consciousness (e.g., perceptual
or sensory “split-off” aspects of the traumatic
experiences, often experienced as inexplicable
physical sensations or a feelings of not sensing
what it is to be “in their bodies”).
C. Appreciation of reality (e.g., tightly con-
structed system of delusional thought
processes surrounding imagined traumatic
events).
D. Relationships (e.g., difficulty trusting others,
revictimization and victimization of others).
75. Which of the following psychometric assess-
ment instruments is the only one that has been
validated for the purpose of diagnostic assess-
ment of DESNOS?
A. Structured Interview of Disorders of Extreme
Stress (SIDES)
B. Traumatic Antecedents Questionnaire (TAQ)
C. Dissociative Experiences Scales (DES)
D. Inventory of Altered Self-Capacities (IASC)

395
Complex Trauma and
Disorders of Extreme Stress
(DESNOS) Part Two:
Treatment
Toni Luxenberg, PsyD, Joseph Spinazzola, PhD, Jose Hidalgo, MD,
Cheryl Hunt, PsyD, and Bessel A. van der Kolk, MD
Dr. Luxenberg is a Clinical Supervisor and Staff Psychologist,
Dr. Spinazzola is the Associate Director of Research & a Staff Psychologist, Dr. Hidalgo is a Staff Psychiatrist;
Dr. Hunt is a Clinical Supervisor, and Dr. Van der Kolk is the Medical Director
of The Trauma Center, Arbour Health System, Allston, MA and Boston University School of Medicine.
The authors would like to acknowledge Margaret Blaustein, PhD for her contributions to this manuscript.
Learning Objective
Clinicians will understand the three basic phases of treatment for DESNOS, as well as
psychotherapeutic and psychopharmacologic techniques that may be helpful in each phase.
The authors conceptualize recovery in DESNOS as entailing three phases. The first is stabilization, where areas of
affect dysregulation, alteration in consciousness, and disturbances in self-perception are addressed. Much of the
work here is psychoeducational—focusing on issues of physical needs, trust, safety, self-soothing, and building sup-
port networks, and not the trauma.
D i r e c t i o n s i n P s y c h i a t r y
Volume 21 Lesson 26
Editor’s Note
Publication Date: November, 2001

The Treatment
of Disorders of Extreme Stress
The treatment of simple PTSD and DESNOS
re q u i re different appro a c h e s . The treatment of
DESNOS is conducted in stages or phases that are gen-
erally agreed upon by clinicians and experts in the field.
Some of the earliest writing delineated three phases,
and these three phases continue to guide tre a t m e n t
t o d a y.
5 0
Se veral extensive re v i ews of phase-oriented
t r eatment are currently ava i l a b l e .
9 2 , 9 3
We will discuss the
main therapeutic tasks and foci of each of the thre e
phases, as well as the different therapeutic strategies
and interventions that are associated with each stage of
t re a t m e n t .
The re c ove ry process is most often conceptual-
i z ed in terms of the following three phases: (1) sta-
bilization, (2) processing and grieving of traumatic
memories, and (3) re c o n n e c t i o n / reintegration with
the world.
2
The first stage invo l ves the establishment
of safety, stabilization, containment, and symptom
reduction. Although treatment should not be con-
s t rued as a strictly linear process, and there is consider-
able overlap between the phases, this first phase o f
t r eatment primarily addresses the areas of affect
d y s r egulation, alteration in consciousness (e.g., dis-
s o c i a t i o n ) , and disturbances in self-perception. T h e
second phase i n vo l ves the work of exploring trau-
matic experiences in depth, and the integration of
those experiences into a coherent life narrative ,
which primarily impacts the patients’ self-perc e p-
tion and ability to be in relationships with others.
The third phase invo l ves focusing on pre s e n t - d a y
i s s u e s — reconnection with peers, and moving on
with life through the exploration of pleasurable
activities, meaningful work, bodily comfort, and
c o n s t ru c t i ve re l a t i o n s h i p s .
5 0
This phase of tre a t m e n t
is primarily concerned with relationships with others
and altering systems of meaning. The stages of re c ov-
e ry are fluid, and patients typically move back and
f o rth between the stages throughout the healing
p r ocess, and even within individual sessions.
Phase One: Stabilization
In this first phase of re c ove ry, much of the initial
w o r k of therapy is psychoeducational. It is necessary
to assist patients in making sense of their experience by
p r oviding them with basic information about the
effects of trauma on individuals, both in the short- and
long-term. Ps ychoeducation should include a rationale
and explanation for specific symptoms, such as affect
d y s r egulation, dissociation, flashbacks, and hyper-
a ro u s a l .
9 4
Ps ychoeducation also includes helping
patients, over time, to identify aspects of their enviro n-
ment that remind them (consciously or otherwise) of
their trauma, thus causing subsequent distress. “Mo o d
l o g s” often help in assisting patients with identifying
w h e r e they we r e and what we r e they thinking, feeling,
experiencing in their bodies, and doing right before
they became distre s s e d . Such identification allow s
patients to begin to evaluate realistically the amount
of danger actually present in their current enviro n-
ments, rather than continually being at the mercy of
their own hypera ro u s a l .
9 5
An example of this occurre d
in the treatment of a patient who felt increasingly anxious
396
Volume 21 Lesson 26Directions in Psychiatry
Phase Two consists of processing and grieving of traumatic memories. He re exposure-based treatments, such as Pro-
longed Ex p o s u re, St ress Inoculation Training, and Cognitive Processing Therapy are useful. Traumatic experiences
should be explored in depth and integrated into a coherent life narrative that primarily impacts the patient’s self-per-
ception and his/her ability to be in relationships with others. The third phase invo l ves focusing on present-day issues,
reconnecting with peers, exploring meaningful work, pleasurable activities, and constru c t i v e re l a t i o n s h i p s .
The authors advocate the judicious use of psychopharmacological agents, especially in the early phase of treat-
ment when disturbing affect is evident. We know that sertraline has been shown to be effective in PTSD; thus this
drug and perhaps SSRIs in general would prove the most useful class of agents. There is a place for benzodiazpines,
used with care, as well as mood stabilizers, and perhaps even stimulants such as methylphenidate. None of these
agents have been adequately studied in treating DESNOS. The clinician can be guided by target symptoms and
experience with PTSD in choosing among them.

and frightened after moving into a new apart m e n t .
T h rough thera py, she was able to identify that this feeling
intensified whenever she walked into her bathro o m ,
which was decorated with floral wallpaper. She was then
able to make the connection between this wallpaper and
the similarly styled wallpaper in the bathroom in which
she was molested as a child. Armed with this inform a t i o n ,
she was able to ask her landlord for permission to re - w a l l-
paper her bathroom, which was granted, resulting in a
resolution of her anxiety and fearf u l n e s s .
Physical Well-Being
In addition to basic psychoeducation about
trauma, attention needs to be given to the person’s
physical well-being and bodily experiences. This
includes addressing relevant health issues (e.g., med-
ication compliance), and the regulation of body func-
tions such as sleeping, eating, and exercise.
2
In seeking
to regulate patients’ physical functioning, the ground-
work is laid for both regulating affect, and addressing
issues of somatization and disruption of bodily experi-
ence. Starting to take care of their bodies is frequently
an important first step in helping patients feel agentic
and in control, and in changing their perception of
themselves as being helpless. Chronically traumatized
individuals cannot begin to tolerate the next phase of
treatment until they have at least a rudimentary famil-
iarity and comfort with their own body and physical
experiences.
Environment
Also at issue in this stage is the patient’s external envi-
ro n m e n t ,
5 0 , 9 4
with focus on practical issues such as hav-
ing a safe living situation, terminating current abusive
relationships, and having adequate access to health care ,
m o n e y, and employment opportunities. Many patients
need to be assisted in obtaining safe housing, re l i a b l e
t r a n s p o r tation, or other practicalities before furt h e r
w o r k in therapy is possible. Fi n a l l y, to combat the dys-
regulation in the lives of DESNOS patients, it is nec-
e s s a ry to incorporate stru c t u re into their live s
t h r ough the implementation of routines and sched-
ules that allow for a sense of pre d i c t a b i l i t y. Many of
these issues, of course, will be ongoing thro u g h o u t
t re a t m e n t .
ISSUES OF TRUST:
Another ongoing issue that is particularly figural at the
beginning of therapy with chronically traumatized
individuals is that of trust. Given their histories of
chronic traumatization in the context of interpersonal
relationships, chronically traumatized individuals tend
to expect similar experiences in both the present and
the future; such individuals may have significant diffi-
culty feeling safe in relationships and being calmed
through interpersonal means. Such individuals con-
duct themselves in ways designed to minimize the
potential for further harm. The consequence of such
behavior is often an interpersonal wariness and dis-
tance that can make relationship building in therapy
an extended process. This can be understood as a
consequence of the interaction between two
domains of difficulty related to the DESNOS con-
struct: problems with relationships, and distur-
bances in self-perception. These areas interact syn-
ergistically causing chronically traumatized
individuals to fear that they cannot be understood
or valued, see others as potential sources of further
mistreatment, and use interpersonal caution as
their primary means of protecting themselves from
anticipated cruelty in the face of their own per-
ceived inadequacies and shameful sense of self.
Trust is likely to be an issue, to varying degrees,
throughout the course of therapy, and may well need
to be addressed continually. Trust will be particularly
important in the initial stage of therapy, as patients are
being asked to enter into an intense interpersonal rela-
tionship (i.e., therapy) at the same time that they are
acknowledging (at least implicitly, through their mere
presence in therapy) how harmed they have been in
the past.
ISSUES OF SAFETY:
In the first phase of recovery, safety is often a focal
issue; no other work can proceed until the patient is
safe.
50
Depression and anxiety can be intense during
this phase of treatment, and often present are issues of
suicidality and self-harm in the form of self-injury,
substance abuse, or eating disorders.
96
Another focus
in this phase of treatment is affect regulation and
the management of PTSD symptoms such as flash-
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part Two: Treatment Luxenberg, Spinazzola, Hidalgo, Hunt, & van der Kolk
397

backs, nightmares, and sleep difficulties. Because of
these factors, this phase is often filled with crisis.
50,97
During this period, it is important not only to address
these problems behaviorally, but also to gain an under-
standing of their psychological meaning for the
patient. Importantly, it is not helpful or advisable for
the clinician to communicate this understanding to
the patient during this phase of treatment. While, at a
later date, it may be very useful for a patient to recog-
nize the psychological “goal” of his or her behavior, in
the service of finding more adaptive means of meeting
that goal (e.g., a woman may realize that she has fre-
quent, intense crying spells because she feels this is the
only way to communicate to her partner that she
needs support and comforting), it may actually be
destabilizing in the first phase of treatment to explicitly
comment on the historical origins of behavior to the
patient. Specifically, patients who are very unstable,
highly defensive, actively self-harming, or using
other destructive means of coping (e.g., drug use)
are unlikely to profit from the connection of the
past with the present, as they are clearly indicating
with their behavior that such connections are cur-
rently intolerable to them. The linking of past expe-
riences with current behavior almost always involves
the evocation of traumatic material, which is to be
avoided during this stage. Once stabilization and con-
structive coping skills have been achieved, the clini-
cian can use the knowledge gained in the previous
phase of treatment to help patients break destructive
patterns of behavior, thought, and affect. Many self-
destructive behaviors can be best understood as reen-
actments of earlier abuse,
55
an internalization of the
abuser and his or her negative messages, or attempts to
pierce dissociative barriers and “feel” something (this
will be explored in more depth later in this lesson).
Those who self-injure commonly state that they do so
to help themselves reduce their level of negative affect.
This is likely due to the release of powerful endoge-
nous opioids that can become a highly addictive
means of managing intense emotions.
98
Pharma-
cotherapy is often an important adjunct to ongoing
psychotherapy to help reduce patients’ reactivity
and hyperarousal, address sleep difficulties, mini-
mize nightmares and other intrusive experiences,
and provide relief from anxiety and depression.
99
CREATING BOUNDARIES
AND ESTABLISHING PATIENT
RESPONSIBILITIES:
Due to the volatility of patients during this phase of
treatment and their intermittent ability to access cop-
ing skills, it is necessary that the therapist take an
active and direct role in therapy.
97
This may include
developing concrete “safety plans” with the steps
patients will take when feeling overwhelmed and
unable to cope. It may be necessary during this phase
of treatment for the therapist to develop rules and
boundaries for out-of-session contact with the
patient.
97
Due to the crisis-oriented nature of this
phase of treatment, some patients will call their thera-
pist frequently, demand extra sessions, and continually
threaten to hurt themselves. Therapists must be clear
in their own minds about the limits of what they are
willing to do, and communicate these limits explicitly
to the patient. Important considerations are: amount
and length of out-of-session contact; availability of
therapist during evenings and on weekends; and use of
hospitalization. Such limits will vary across cases, and
they may also change throughout the course of treat-
ment; these should be explained to the patient as they
change. It is important for patients to be expected
to take responsibility in the management of their
affect.
97
A therapist who continually “saves" the
patient only serves to reinforce the patient’s own sense
of helplessness and powerlessness. It is important to
understand that suicidal, self-harming, or "out-of-
control" behavior serves the crucial function, for
patients diagnosed with DESNOS, of regulating intol-
erable feeling states in the absence of more adaptive
self-soothing strategies.
BUILDING SELF-SOOTHING
CAPACITIES IN PATIENTS:
It will be important during this first phase of treat-
ment to help patients develop the capacities for
self-care and self-soothing that they were not able
to develop previously.
55
Having distanced themselves
from their bodily experiences, patients will often have
limited awareness of what would be helpful to them
when they are distressed. It is often helpful for the
clinician to present the patient with a range of self-
soothing options; the patient should be instructed to
398
Volume 21 Lesson 26Directions in Psychiatry

consider self-soothing an experiment, and try different
options to see what works and what does not. This
trial-and-error attitude allows the patient permission
to reject methods that are not helpful, and to not view
an unsuccessful application of a technique as a "fail-
ure." It may also be helpful for some patients to do
their own related reading.
100,101
Initially, lists of self-
soothing strategies written down on paper are
often necessary because patients may not be able to
remember what self-soothing options they have
available when they are very distressed. It is impor-
tant to consider, however, the danger that both
patients and clinicians may ultimately use self-sooth-
ing skills as a means of avoiding the patients’ distress-
ing emotions. Patients need assistance in strength-
ening their emotional tolerance; self-soothing
strategies are best thought of as a means of helping
patients bear and move through their uncomfort-
able emotions, rather than as a means of warding off
such emotions.
It is helpful for patients to be encouraged to
explore coping skills that encompass as many
senses as possible. This addresses the patient’s separa-
tion from his or her own body and physical needs.
Patients often need assistance in accessing and most
effectively using their own capacities for tolerating and
managing affect. Exploration of options can build a
sense of empowerment. Patients can be encouraged, for
example, to buy a warm, soft article of clothing to wear
when upset, develop a list of comforting foods, identify
music that is calming, etc. Care should be taken, however,
to avoid potential traumatic reminders while exploring
soothing activities. For example, bubble baths and mas-
sages may be very upsetting and anxiety-provoking for
individuals who have been sexually abused or assaulted.
A number of relaxation techniques can be quite
beneficial for patients, such as progressive muscle
relaxation, deep breathing, and guided imagery.
100
The goal should be for patients to learn to perform
these exercises themselves, without the assistance of
the therapist, so that they can become active in man-
aging their own emotions. Care should be taken, how-
ever, because states of relaxation can sometimes precipi-
tate panic or anxiety in traumatized individuals. One
technique that can be particularly helpful, both in and
out of session, is having the patient imagine a con-
tainer of some kind (patients have imagined every-
thing from shoe boxes to bank vaults),
100
and to visual-
ize putting distressing feelings, sensations, memories,
or images into the container and then securing it in
some manner; sometimes a simple lock is sufficient,
and other times, the container has to be sunk to the
bottom of the ocean or shot into space). As van der
Kolk and Fisler have pointed out,
102
traumatic mem-
ory may well be stored in somatosensory formats
rather than verbal formats. This may, therefore, neces-
sitate the use of nonverbal techniques for working
with memory and containing affect. Such techniques
may involve movement, touch, artwork, dance, etc.
103
Dialectical Behavior Therapy
Dialectical Behavioral Therapy (DBT), developed by
Marsha Linehan,
91
is an example of a treatment that
assists patients in developing the skills to deal with
affect regulation, and DBT can be extremely helpful
during the stabilization phase of treatment. DBT also
has components such as building and reinforcing rela-
tional skills. Although DBT is an entire treatment
program, including coordinated group and individual
work, there are groups offered by agencies based on
the concepts of DBT, and these can be helpful as
adjunctive treatment, or sometimes as preparatory
treatment for individual work.
SUPPORT SYSTEMS:
It is also important in this phase of treatment to assist
patients in mobilizing and utilizing as many sup-
port systems as possible.
50
This helps begin to
address their difficulties in relationships with others.
Group treatment, as mentioned above, can be helpful,
as can 12-step programs. Day treatment programs and
connections with other agencies can often add addi-
tional support, particularly during times of crises.
Patients should be encouraged to identify supportive
individuals in their environment who can be relied
upon in times of distress. It is often helpful to assist
patients in developing a hierarchy of resources in their
environment by asking them to identify individuals
with whom they can: (1) have fun and distract them-
selves from their difficulties; (2) share that they are
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part Two: Treatment Luxenberg, Spinazzola, Hidalgo, Hunt, & van der Kolk
399

upset and receive some comfort, without going into
details; and (3) share their distress on a more intimate
level and be understood and supported. Individual
psychotherapy––and individual therapists––alone are
typically not adequate for addressing all of the issues
that will arise in the course of treatment during this
initial stage.
Focus on Stabilization
During this phase of treatment, the above issues
(physical needs, trust, safety, self-soothing, and the
building of support networks), and not the trauma,
should be the focus of the treatment. Therapy dur-
ing this stage of treatment should be reparative, not
explorative. In a very real sense, patients do not have
the tools they need at this stage to tolerate trauma-
focused work; forcing patients to do such work before
they are ready risks symptom exacerbation, escalated
self-injury and suicide attempts, premature termina-
tion of treatment, and retraumatization.
50,55
In fact, it
is frequently necessary to stop patients from delving
into their trauma, and explain to them the necessity of
making sure that they have consistent access to all the
necessary skills and supports before doing so.
97
This
stage may be quite brief for acutely traumatized
individuals, but it can be quite lengthy, sometimes
spanning years in treatment, for patients who meet
the criteria for DESNOS.
97
Vignette
“ J eannette,” a 34-year-old woman, was
re f e r r ed to a therapist after being hospital-
i z ed for several weeks subsequent to attempt-
ing to kill herself by taking several medica-
tions she had on hand and consuming a
bottle of wine. This was Je a n n e t t e’s fourt h
hospitalization in the last two years. The pre-
vious hospitalizations had all been pre c i p i -
tated by similar suicide attempts, or self-
i n j u ry in the form of burning herself with a
c i g a rette lighter. Jeannette explained to hos-
pital staff that she had to burn herself some-
times, because otherwise she would “g o
c r a z y,” or start crying and never stop. In d e e d ,
she was observed to scream and cry for
extended periods of time over what appeare d
to be minor stressors in the hospital (e.g.,
having to wait to use the telephone). After
one conflict with another patient, she
banged her head against the wall and had to
be restrained. Du r ing the restraint, Je a n n e t t e
a p p e a red to be experiencing a flashback, cry-
ing out that she wouldn’t take her panties off
and asking repeatedly for her grandmother,
who had raised her for several years duri n g
her childhood.
Jeannette reported that her childhood had
been a “nightmare,” with her bouncing
between relatives and foster homes as her
mother went in and out of drug treatment
programs and lived with a series of abusive
men. Jeannette refused to talk about any of
her mother’s boyfriends or her experiences
with them, simply stating that “I hope they
all rot in hell.” Jeannette was removed from
her mother’s care for the first time when she
was six months old. Jeannette insists that
her mother did the best she could, but she
acknowledges that she was often without
food or heat as a young girl, and she was fre-
quently left to care for her two younger sib-
lings when her mother would disappear for
several days at a time. Jeannette has memo-
ries, over which she experiences intense
shame, of going through the neighbors’
trashcans, looking for food for herself and
her siblings. As an adult, Jeannette became
involved with a violent man, and she used
drugs heavily during this time period.
Jeannette was able to leave this man when
she became pregnant and entered a detox
program, which she successfully completed.
She reports that the birth of her son turned
her life around, but that she finds the
stresses of single motherhood to be over-
whelming at times.
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Volume 21 Lesson 26Directions in Psychiatry

In addition, Jeannette reports significant
sleep problems, often not falling asleep
until two or three in the morning, because
she “can’t turn her mind off and stop
remembering stuff.” Jeannette has frequent
nightmares whose content she cannot
remember upon waking. Jeannette also
reports that “everything” scares her, and
that she screams at any sudden noise or
movement. She particularly is frightened by
men and reports that she once broke a man’s
nose after being startled when he
approached her from behind to return an
item she had dropped from her purse.
Jeannette reports that she no longer abuses
drugs or alcohol, but finds she sometimes
drinks and uses marijuana to temporarily
escape from domestic pressures and master
her fear. Despite this, she often has panic
attacks when away from home. Due to these
attacks, she no longer can ride in crowded
subway cars.
Jeannette is significantly overweight and
reports feeling depressed about this. She
experiences chronic heartburn which she
reports was not helped by her medication,
so she discontinued taking it and has not
sought other solutions, stating that “noth-
ing will help.” Jeannette reports that the
only things that help her feel better are
“stuffing” herself with food and spending
time with her son. She has no friends, stat-
ing that the only person she needs is her
son. She has intermittent contact with her
mother, but she does not see either of her
siblings, although they live in the neighbor-
ing town. Jeannette works part-time, but
she finds that she often has difficulty focus-
ing on her work, because she is thinking
about “all the bad things that happened to
me.” This has caused her to be fired on sev-
eral occasions. More typically, however, she
quits when she becomes involved in a dis-
pute with a fellow employee or boss.
Jeannette also works as a free-lance artist,
occasionally selling illustrations to maga-
zines. Although she loves this work, she
finds it hard to make a living.
Jeannette has been in therapy prior to this
incident, and she reports that none of the
therapists truly understood her, and that
she ultimately left therapy each time, feel-
ing disappointed and betrayed again. When
asked what she does to help herself cope
with the difficulties in her life, Jeannette
replied, “Just not think about things, I
guess. Or I just cry and cry until I’m just too
tired to care.” Jeannette also reported stock
piling broken glass. Although she has never
actually cut herself, she states that just
knowing it is there comforts her.
Conceptualization
It is important to note that this vignette is not meant to
p rovide a compre h e n s i ve treatment plan that addre s s e s
all possible aspects of treatment. It is meant, rather, to
p rovide an illustration of typical considerations during
the first phase of treatment. Not all of the tre a t m e n t
aspects mentioned previously will be re l e vant for any
one individual patient, and some will take pre c e d e n c e
over others.
Jeannette was clearly in the first phase of trauma
t reatment—she re q u i red significant stabilization before
other work could commence. This was clear from the
f o l l o wing information: (1) Jeannette currently had ve ry
a c t i ve PTSD symptomatology which was interfering to
a great extent with her daily functioning; (2) she was
self-medicating through alcohol and drug use; (3) she
had ve ry destru c t i ve and/or ineffective means of coping;
(4) she was not currently making significant use of con-
s t ru c t i v e coping strategies; (5) she had a minimal sup-
p o rt system; (6) and she was experiencing significant
affect dysre g u l a t i o n .
It is important to remember that not eve rything can
be accomplished at once. Priorities had to be set, and
the initial work focused on helping Jeannette to build
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part Two: Treatment Luxenberg, Spinazzola, Hidalgo, Hunt, & van der Kolk
401

up a re p e rt o i re of specific, concrete means of coping
with distress. Je a n n e t t e’s therapist re f e r red her to an
a d j u n c t i v e DBT gro u p, feeling that this would prov i d e
both a skills-focused atmosphere, as well the beginnings
of the support network that Jeannette so clearly needed.
The therapist also re f e r red Jeannette for a psyc h i a t r i c
e v aluation, and she was ultimately placed on seve r a l
medications to address her sleep difficulties, intru s i ve
s y m p t o m a t o l o g y, and anxiety, as these we re seen as
being the largest, most immediate, impediments to her
daily functioning. In addition, the therapist re c o m-
mended that Jeannette consult with her doctor about
t rying additional medications for her heartburn, which
she ultimately did, and found a medication that man-
aged her discomfort quite well. This accomplished sev-
eral goals beyond the obvious one of symptom re l i e f :
(1) it taught Jeannette that her body was an import a n t
and worthy focus of attention; (2) it encouraged Je a n-
nette to begin to care for herself on a basic level; and (3)
it allowed Jeannette to experience success in taking
charge of an aspect of her life. After additional eva l u a-
tion, the therapist determined that Jeannette was not
c u r r ently using drugs and alcohol at a level that necessi-
tated a higher level of care (i.e., inpatient), but he re c-
ommended that Jeannette join an Alcoholics Anony-
mous gro u p, both to pre vent further and heavier use
f r om occurring, and again, to begin to build up a sup-
p o rt i v e social network.
The therapeutic work initially focused on helping
Jeannette identify when she was becoming distraught
or overwhelmed. This was accomplished primarily
through helping Jeannette learn to focus on her body
signals that let her know that she was in distress. This
was difficult for Jeannette to do, not being very aware
of her body, and finding sensation in it to be upset-
ting. The therapist, therefore, taught Jeannette how to
do progressive muscle relaxation as a gentle way of
having her become more familiar with her body and
its signals. Once this was accomplished, Jeannette was
able to notice when she was becoming hyperaroused
and distressed. In an attempt to help Jeannette learn to
recognize “shades” of affect, the therapist taught her to
visualize different feelings as different colors (e.g.,
anger was red), and equate different hues with differ-
ent levels of that particular emotion. Over time, they
identified the shades that signified that Jeannette was
experiencing a problematic level of an emotion. This
technique strengthened one of Jeannette’s existing
resources, her artistic skill.
The next step in treatment was to help Jeannette
begin to identify means of calming herself when she
noticed that she was experiencing distress. Initially,
Jeannette handled distress by calling the therapist and
demanding that he help her because she felt like “she
was going to die.” The therapist explained that it was
ultimately counter-productive for him to “sweep in”
and save Jeannette from her feelings, because this
would prevent her from both learning how to handle
such situations herself and reinforce that feelings
themselves were dangerous and to be avoided, rather
than dealt with. Over time, an agreement was reached
that Jeannette could call her therapist if she had tried
at least three different coping techniques and experi-
enced no lessening in distress. Such calls were under-
stood to be time-limited, and for the purpose, not of
solving whatever the specific problem might be, but
for further strategizing about what Jeannette could do
to manage her affect. The therapist encouraged Jean-
nette to practice muscle relaxation and visualization of
a peaceful scene several times a day, so that she became
facile at their use and could easily employ them when
in distress. The therapist helped Jeannette deepen her
experience of being relaxed and calm by employing
her artistic talents and having her draw a peaceful
scene for her to imagine when distressed, and a picture
of what it felt like to be relaxed and calm. Jeannette
hung both of these in her bedroom and found looking
at them was more effective than imagining the scenes
in her head.
Finally, the last focus of stabilization in work with
Jeannette was on helping Jeannette to address her fear
of public transportation and her interpersonal difficul-
ties with co-workers. Both of these problems were
compromising Jeannette’s ability to earn a living, and
she identified them as the areas in which she needed
the most help, so that her life could become more rou-
tine and manageable. This work was primarily cogni-
tive-behavioral in nature, helping Jeannette to learn to
402
Volume 21 Lesson 26Directions in Psychiatry

identify the thoughts that were triggering both the fear
and anger that she found to be so problematic, and
then replacing those thoughts with constructive ones
that stopped the fear and anger “cycles.” Jeannette was
able to use her already-learned relaxation skills to
undergo progressive imaginal exposure to riding pub-
lic transportation, until she became able to effectively
manage her fear and was able to ride on public trans-
portation without having panic attacks. She also
learned how to notice when she was becoming angry
enough to compromise her position at work, and calm
herself down and take “timeouts” so that she could
resolve the conflict in an appropriate fashion.
After a year of treatment, Jeannette had not been
hospitalized, and had only one instance of self-injury
early on in treatment. She was attending therapy regu-
larly, and had been able to maintain her job over the
last six months. She had made a few friends through
the various groups that she attended, and several times
when in distress, she had called these individuals,
rather than using drugs or alcohol, or self-injuring.
She still refused most invitations from others, how-
ever, preferring to remain at home. She was sleeping
regularly, and had only infrequent nightmares and
intrusive thoughts. She still struggled with anxiety, but
found she was able to manage it so that she no longer
experienced full-blown panic attacks. Jeannette also
still struggled with significant feelings of depression,
and had recently begun to feel despair that she would
never have an intimate relationship. She stated that
now that her life was not so chaotic and her symptoms
were not so crippling, she was becoming aware of an
intense loneliness that she had not expected. She
stated, however, that, on balance, her life was much
improved from a year before, and she felt much more
confidence in herself to manage whatever came her
way. She and her therapist began to discuss the possi-
bility of exploring the impact of some of her traumatic
childhood experiences on her current interpersonal
functioning, and how she felt about herself. Jeannette
realized that this was the next step for her, and she felt
both apprehensive and excited about breaking away
from old, trauma-based ways of understanding herself,
others, and the world around her.
Phase Tw o : P r ocessing and
G r i e ving of T r a u m atic Memories
The second stage of treatment involves the work of
exploring the traumatic memories in some depth.
The purpose of this stage in recovery is the integra-
tion of traumatic memories into a coherent narra-
tive about one’s life,
50,95,104
along with desensitiza-
tion of the intense negative affect associated with
these memories. Ultimately, the memories evolve
from being the focal point of an individual’s life to
being a set of experiences that occurred within a larger
context.
105
This work helps address the alterations in
these individuals’ meaning systems by instilling a sense
of hope for the future that it is no longer merged with
a traumatic past. In addition, in processing their trau-
matic memories, many individuals find that they
change their perceptions of others and their expecta-
tions in relationships, allowing them to build more
healthy relationships than previously possible.
At the same time, whereas ample empirical evidence
supports the necessity of exposure/trauma processing
in the treatment of patients with simple
PTSD,
106–108,110–116
the necessity of phase two interven-
tion for clinical improvement in chronic trauma
patients with PTSD and DESNOS is less clear and
awaits empirical substantiation. In some instances, the
specifics of a patient’s circumstances may argue against
trauma processing. An example would be an elderly
patient who is dying of cancer and who also has
DESNOS related to numerous traumatic childhood
experiences. In this case, a focus on stabilization and
the management of anxiety may well be indicated.
The decision to embark on the work of trauma pro-
cessing should be made according to the exigencies of
the life of each patient, and the patient’s own wishes
must be taken into account.
55
Moreover, in our clinical
work we have frequently come across the treatment-
induced decompensation of DESNOS patients, sec-
ondary to premature introduction of trauma process-
ing techniques before the attainment and maintenance
of safety and stabilization described in phase one. In
these instances, DESNOS patients are flooded with,
and affectively overwhelmed by, a resurgence of long-
contained traumatic memories that have been acti-
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part Two: Treatment Luxenberg, Spinazzola, Hidalgo, Hunt, & van der Kolk
403

vated by exposure-based interventions without ade-
quate development of the requisite internal coping
resources to tolerate these memories and their associ-
ated cognitive, affective, and somatic correlates.
Accordingly, the importance of timing, sequencing,
and titration of phase two intervention with
DESNOS cannot be underestimated.
This work should not be attempted by individu-
als who are not qualified to handle traumatic mem-
ories and the intense affects and behaviors that
may ensue. Specific training in the therapeutic han-
dling of traumatic content should be sought before
such work is undertaken. The primary goal of this
phase of treatment is to have the patient acknowl-
edge, experience, and normalize the emotions and
cognitions associated with the trauma at a pace
that is safe and manageable. The primary rationale
for the work with traumatic memories is to provide
the patient with symptom relief, integrate split-off
aspects of the self and the traumatic experience, and to
allow the patient to shift focus to nontraumatic
aspects of his or her life. As van der Kolk
36
has noted,
trauma is often registered in the body as unspeak-
able terror, and the processing of traumatic experi-
ences can allow individuals to put their experiences
into words, thus robbing these experiences of their
disruptive, often somatically based or kinestheti-
cally based power. Processing may also be achieved
through nonverbal means as well, such as body-ori-
ented therapies, self-defense training, and other physi-
cally based means of moving through emotions, dis-
covering resources, and seeking empowerment.
EXPOSURE-BASED TREATMENTS:
It is important that graduated exposure be incorpo-
rated into the second phase of treatment with the sup-
port of the therapeutic relationship. In controlled
exposure situations, traumatic memory is activated
along with any associated affect, with the therapeutic
aim of modifying that memory and reducing or dis-
charging anxiety and negative affect associated with
the memory. This allows the memory to become less
rigid and distressing and more like memories of non-
traumatic events.
95
There are a number of highly
effective exposure-based PTSD treatments. Many
of these treatments, such as Prolonged Exposure,
106
Stress Inoculation Training,
107
and Cognitive Pro-
cessing Therapy (CPT),
108
are cognitive-behavioral
in nature and focus on patients’ cognitions and
attributions about both the traumatic event(s) and
themselves. The common theme is that patients are
purposefully exposed to their own traumatic memo-
ries until they learn to tolerate the attendant emotions,
and a diminution of anxiety occurs. In CPT, a further
step is taken in which patients’ faulty beliefs (e.g., “It
was my fault. I’m bad”) are then challenged and more
adaptive beliefs sought. Eye Movement Desensitiza-
tion and Reprocessing (EMDR) is another expo-
sure-based intervention that has been shown to be
very effective in dealing with traumatic experi-
ences.
109,110
In fact 60,000 clinicians around the world
have been trained in EMDR––far more than all other
techniques combined. This technique involves calling
up traumatic memories, attendant emotions, and asso-
ciated faulty beliefs while undergoing bilateral stimu-
lation (e.g., through following rhythmically moving
objects with the eyes; hand taps; or alternating audi-
tory tones). This allows the processing of memories in
a manner that is often faster than that achieved by ver-
bally based treatments.
111,112
EMDR has been found to
be at least as effective as other exposure-based treat-
ments for trauma.
113–115
While cognitive-behavioral treatment (CBT) has
been proven to be a very effective form of therapy for
PTSD,
106,111,116
there are indications that it is not suffi-
cient for DESNOS populations. Fairly high dropout
rates are frequently reported, and some studies have
even found significant morbidity.
106,107,117
For example,
Jacycox and colleagues
118
found that 67.5% of their
sample was still symptomatic and exhibiting poor lev-
els of functioning after treatment. According to Ford
and Kidd,
90
only one in three participants enrolled in
the CBT treatment studies they examined were able to
complete the study and show clear treatment gains.
Some studies have even needed to be prematurely ter-
minated, due to significant increases in symptomatol-
ogy.
119
The literature indicates a myriad of factors that
may contribute to adverse outcomes in exposure-based
404
Volume 21 Lesson 26Directions in Psychiatry

treatments, such as high and persistent levels of
anger,
120–122
attitudes of mental defeat,
123
feelings of
alienation and being permanently damaged,
124
and the
experience of guilt and shame.
125
While most individu-
als may experience at least some of these feelings at
some point in their lifetime, what characterizes the
chronically traumatized is the persistence and perva-
siveness of these feelings. Individuals, for example,
may feel chronically ashamed, and therefore tolerate
abusiveness in relationships, not take good care of
themselves physically, and not seek help when in dis-
tress. The parallel between these sources of treatment
failures and the categories of DESNOS is striking.
The predictors of treatment failure appear to be vari-
ous expressions of precisely the symptoms (e.g., affect
dysregulation) that are central features of the
DESNOS diagnosis.
Combination Treatments
Effective treatment for individuals who meet the crite-
ria for DESNOS requires both affect regulation (phase
one) and exposure (phase two) to be addressed. Cloitre
and colleagues
123
have combined skills-based training
in affect and interpersonal regulation (STAIR) with
CBT-based exposure and emotional processing.
106,107
Cloitre’s model is the first such model to formally
incorporate both aspects of treatment, and it has been
found to be effective in treating chronically trauma-
tized individuals in a relatively short period of time
(16 weeks). It is important to note, however, that
many of Cloitre’s participants still experienced signifi-
cant dysfunction at the end of the study; according to
a letter from M. Cloitre they frequently expressed fear,
anger, and resentment that therapy was being termi-
nated (personal communication, January 2001).
STABILIZATION ISSUES
DURING THE PROCESSING PHASE:
What has not been formally articulated anywhere in
the literature is the need to move back and forth
between stabilization and processing, and how and
when to make those transitions. To that end, the
research group at The Trauma Center, led by Bessel
van der Kolk, is currently working on developing a
treatment manual that makes explicit how one deter-
mines when to shift back and forth between stabiliza-
tion and processing, both within and between ses-
sions. (A grant is currently under review to develop
this manual).
It is not unusual in this second phase of treat-
ment for safety and stabilization concerns to resur-
face, particularly when key memories are addressed
that involve themes of violation, betrayal of trust,
loss of the capacity to protect oneself, and impo-
tence of others to protect one from danger. When
this occurs, the safety issue should be addressed, strate-
gies to deal with it reviewed, and stabilization again
achieved before the work of processing continues.
Sometimes this may entail a considerable amount of
time and involve a number of sessions. Other times, it
may be addressed relatively quickly within session.
During processing work it is crucial for the clin-
ician to pay very careful attention to signs that the
patient is becoming overwhelmed. This can be a
subtle procedure, and questions of intensity and dura-
tion must be addressed––is the patient somewhat anx-
ious during session, or does she or he have a series of
panic attacks after leaving the session? The former is
potentially a sign that processing is occurring, while
the latter may be a sign that basic stabilization has
been breached and needs to be repaired. When assess-
ing level of distress, the clinician should attend to
breathing, posture, and gaze, as well as the patient’s
ability to formulate thoughts and sentences, to
respond to the clinician, and to interact in an adult
manner.
DISSOCIATION:
Although it is not possible to give a thorough treat-
ment to the subject here, one very important consider-
ation in balancing stabilization and processing is a
patient’s level of dissociation. (The interested reader
should refer to the reference list for articles that
explore this area in greater detail. No.126–133) As
mentioned previously, dissociation is a way for
patients to “split off” aspects of their experience and
insulate the larger system from the emotions, beliefs,
assumptions, and sensory and somatic experiences
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part Two: Treatment Luxenberg, Spinazzola, Hidalgo, Hunt, & van der Kolk
405

associated with certain events. This can happen along
any of four dimensions of “knowing”––behavior,
affect, sensation, and knowledge (BASK model of dis-
sociation).
44
Dissociative experiences vary in intensity,
ranging from persistent forgetfulness to engaging in
behavior of which one later has absolutely no memory.
Many chronically traumatized individuals experience
significant levels of dissociation,
126
and this can have a
critical impact on treatment as patients who are disso-
ciated are not emotionally available for the integrative
work of therapy.
Clinicians must pay close attention for signs of
dissociation so that they can assist patients in
“grounding” themselves. Occasionally, dissociation is
dramatic, involving eye rolling or eye fluttering; more
frequently, it is relatively subtle, consisting of blank
stares, inattention, or fixed looks that seem to “go
through” the clinician. A gentle way to explore possi-
ble dissociation is to ask a patient “What’s happening
right now for you?” or “Where are you right now?” In
extreme cases, the patient may be unresponsive, but,
typically, patients can report feeling “fuzzy,” “out of
it,” or otherwise not engaged in therapy. The therapist
can then assist the patient in becoming focused again.
This might entail having the patient look around the
room and describe objects, identify colors, or feel tex-
tures. Strategies for combating dissociation should
involve all of the senses and a gentle focus on the
patient’s physical body and immediate surroundings.
Movement or change of posture or position may also
be helpful. Patients should be encouraged to keep
their eyes open to maintain contact with their sur-
roundings and the clinician.
Patients can be taught to use these same grounding
techniques themselves, outside of session. Often,
patients will develop their preferred methods for cop-
ing with dissociation, and carry around “grounding
objects” with them, such as smooth stones to rub, sour
candy to suck, or vials of scented oil to smell. In addi-
tion, patients can also be taught to purposefully disso-
ciate and then “reassociate.” This puts the dissociation
under their control; the most important aspect of this
technique is that patients learn how to break their own
dissociative states. This can be done by pairing a sim-
ple physical stimulus (e.g., making a fist) with emer-
gence from a dissociative state, so that the stimulus
can be used at the first signs of unplanned dissociation
and deter it.
Vignette
“ Jo n a h” is a large, muscular, and slightly
ove rweight 35-year-old single Ca u c a s i a n
male employed full-time as a carpenter. He
l i v es in a rural community in a house that he
rents with four other men, most of whom
w o rk for the same construction firm as
Jonah. Jonah was re f e r red for evaluation and
trauma-focused treatment by a pastoral
counselor secondary to increased difficulty
c o n t r olling anger, concentration pro b l e m s ,
and intermittent violent outbursts with
male cow o rkers and housemates. T h e s e
p r oblems had recently become exacerbated
to the extent that his employment and living
arrangements we re in jeopard y.
A history of Jonah’s present illness revealed
that he suffered chronic back pain from a
work-related injury three years ago. Jonah’s
medical providers, however, believed that
the continued severity of this back pain was
in excess of what could be attributable to his
specific form of injury. The suspicion that
psychological problems exacerbated Jonah’s
level of chronic pain resulted in a consulting
physician asking Jonah (approximately 1
year ago) whether he had any history of
child maltreatment or abuse: As such, a
childhood history had anecdotally been
observed by this physician to be associated
with chronic pain presentations. These
questions reactivated Jonah’s long-sup-
pressed, albeit never forgotten, memories of
repeated beatings followed by sexual
molestation for a period of approximately 2
years as a prepubertal early adolescent at the
hands of a trusted adult male recreational
counselor, “Jake.”
406
Volume 21 Lesson 26Directions in Psychiatry

When Jonah’s memories of childhood
molestation were reactivated, they were
accompanied by a resurgence of intense
emotional distress including feelings of
anger, shame, aggressive ideation, and
desire for retaliation. This reactivation pre-
cipitated increased volatility and fighting
with his coworkers and housemates to near-
intolerable levels, such that both his
employer and housemates warned Jonah
that if he did not get help he would have to
leave. Having maintained close ties to the
church throughout his life, Jonah initially
sought support through a pastoral coun-
selor in his local parish, with some limited
relief of symptoms. Consultation with a
local psychiatrist led to prescription of anti-
depressant and anxiolytic medication, again
with limited results. Having attended a
training workshop offered through our
Trauma Center, the psychiatrist recom-
mended that Jonah undergo an evaluation
to assist with treatment planning and assess
the appropriateness of treatment involving
the processing of traumatic memories.
A comprehensive psychological and psychi-
atric evaluation at our clinic was conducted.
This evaluation revealed Jonah’s history of
childhood maltreatment to have been com-
plicated by his experience of preferential
treatment and affection by the perpetrator
before and after instances of abuse. Further,
the abuse occurred against the backdrop of
parental emotional neglect and disapproval,
scholastic problems, and social rejection by
peers. Jonah’s father was a minister whom
Jonah perceived as stern and unavailable.
While Jonah identified his mother as a com-
paratively greater source of affection and
nurturance, he explained that due to his
family’s financial hardship he rarely saw his
mother as she was typically required to
work two jobs and suffered from exhaustion
and frequent physical illness. In contrast,
Jonah’s recreational counselor through the
church took special notice of and interest in
Jonah and gave him unique privileges and
responsibilities, including serving as his
assistant in maintaining the rectory
grounds. These activities became a source
of pride and competence for Jonah.
When his special “friendship” with Jake
escalated into secret beatings and molesta-
tion in the gardening shed, accompanied by
alternating expressions of endearment and
debasement, Jonah experienced deep
ambivalence and confusion. Unable to
report these violations, both out of fear of
being labeled “crazy” or “perverted,” as well
as fear of losing his important attachment
to Jake, Jonah quietly endured this abuse
and suppressed his growing confusion
about normal sexual behavior and feelings.
His approaching puberty added to Jonah’s
inner sense of turmoil, shame, and self-
debasement.
Jonah ultimately dropped out of school at
age 16 and began working as a carpenter’s
apprentice. Soon thereafter he moved out of
his family home. Jonah’s twenties were char-
acterized by hard physical labor, periodic
heavy drinking, and occasional violent
brawls with men at bars. Jonah reported
having a number of acquaintances and
casual friends, and explained that he rarely
had difficulty finding other men with
whom to room or socialize. However, while
perceived by his peers to be at core a kind-
hearted and well-intentioned person,
Jonah’s unpredictable temper and intermit-
tent violent streak, in addition to his
guarded distrust of others, prevented him
from forming more meaningful friendships.
Similarly, his experience with dating was
extremely limited and short-term.
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part Two: Treatment Luxenberg, Spinazzola, Hidalgo, Hunt, & van der Kolk
407

Conceptualization
Findings from the evaluation indicated that Jonah was
currently suffering from DESNOS, in addition to
PTSD. Further, while Jonah had considerable access
to various environmental resources, including sup-
portive peers, family members (by this point in his
life, Jonah had reconciled his relationship with both
his parents, who lived nearby and were available to
Jonah for ongoing support), and church involvements,
he was not very adept or consistent in making use of
these resources. Jonah also lacked adequate internal
coping resources to reduce and prevent the buildup of
anxiety and aggressive feelings. In fact, Jonah per-
ceived himself as unable to tolerate the overwhelming
feelings of shame and anger that he associated with his
history of molestation and the subsequent confusion
and ambivalence he experienced regarding the emer-
gence of developmentally normative sexual desires.
Jonah believed himself to be defective in the area of
relationships, and felt that he was doomed never to
achieve a normal intimate relationship with a woman.
Consequently, he alternated between fearful avoidance
of contact with women and finding himself compelled
to test appropriate boundaries with typically younger
female peers involved in church activities. Although
these interactions never lead to inappropriate physical
contact, on several occasions Jonah needed to be redi-
rected by church elders and instructed to discontinue
interactions with young women in the church who
had become intimidated by his excessive attention,
unannounced visits, and jealousy in response to their
friendships with other young men in the community.
Treatment began with psychoeducation about the
long-term effects of childhood trauma on the mind
and body, including introduction of the PTSD and
DESNOS diagnoses and the phase-oriented model of
trauma treatment. Explanation of the causes and
effects of these diagnoses, and of DESNOS in particu-
lar, provided a sense of comfort and increased self-
understanding for Jonah, serving as an explanatory
model for the confusing array of emotional, interper-
sonal, somatic, and self-image difficulties he had been
experiencing since adolescence.
Treatment began with a “Phase On e” focus on
establishing an internal sense of safety and self-con-
t rol and the increased stabilization and containment
of angry affect. The goal was to eliminate outbursts
of physical aggression by identifying and blocking
p recipitants of this behavior through the implemen-
tation of a regimen of coping techniques. These cop-
ing techniques heavily relied on elements of D i a l e c t i-
cal Behavior T h e ra py ( D BT) and included
incorporation of EMDR-based guided imagery tech-
niques to help Jonah develop an internal sense of
s a f e t y, self-acceptance, and capacity to self-soothe in
the presence of situational stress. In addition, on the
basis of the psychiatric medication evaluation at our
clinic, a mood stabilizer was added to Jo n a h’s med-
ication re g i m e n .
C o n c u r rent behavioral interventions employe d
with Jonah included daily stress logs in which he
re c o rded morning, afternoon, and evening stress lev-
els in conjunction with medication compliance, use
of DBT and EMDR skills, and adherence to a physi-
cal therapy regimen. Jonah demonstrated good com-
pliance with these treatment efforts, and over a
period of 8 weeks demonstrated a noticeable incre a s e
in his capacity to tolerate and appropriately expre s s
his emotions, including feelings of anger and shame
associated with his trauma. Incidents of physical
a l t e rcations we re dramatically reduced. On the basis
of these treatment gains, plans to move tow a rd the
p rocessing of traumatic memories we re discussed and
mutually agreed upon.
Preparations to begin this phase of intervention,
however, lead to marked anticipatory anxiety in Jonah
that ultimately precipitated an emotional decompen-
sation and resurgence of overwhelming affect, culmi-
nating in the first physical altercation with peers in
over 2 months. Consequently, trauma-processing ini-
tiatives were put on hold and Phase One safety stabi-
lization efforts were resumed. Successive attempts to
begin trauma processing resulted in similar, albeit
somewhat reduced, periods of emotional decompensa-
tion. Over time this pattern revealed itself to be a non-
deliberate and yet not entirely unconscious attempt by
Jonah to sabotage the treatment to avoid having to
face the emotional pain and fear anticipated to emerge
once he began the process of intentionally exposing
himself to memories of his traumatic experience.
408
Volume 21 Lesson 26Directions in Psychiatry

At this point treatment efforts focused on empathic
and direct confrontation of this pattern, with
acknowledgement of his treatment progress thus far
and validation of his fears about proceeding with the
next step of treatment. Psychoeducation regarding the
normalcy of this reaction and at the same time the
impact of avoidance on anxiety maintenance and
treatment impasse led to increased insight and aware-
ness for Jonah. A titrated model of trauma processing
was discussed with the patient, and the metaphor of a
dam with controlled release and filtration of small
amounts of water was employed.
Phase Tw o i n t e rvention for Jonah invo l ved use of
EMDR to facilitate the imaginal exposure to and desen-
sitization of targeted traumatic memories. To begin this
w o r k, a hierarchy of specific memories of Jo n a h’s experi-
ence of beatings and sexual molestation was identified.
Gi ven Jo n a h’s marked apprehension about this phase of
t r eatment and limited capacity to tolerate ove rw h e l m-
ing affect, it was decided to begin processing with the
least distressing memory of these experiences. W h i l e
p r ocessing feelings and beliefs associated with this
m e m o ry, it was also necessary to process associated feel-
ings of ambivalence about the abuse because Jonah was
made to feel special by Jake while feeling ove r l o o k e d
and undervalued by his pare n t s .
As treatment progressed Jonah experienced
increased self-control and reduction of aggressive
behavior with peers. Jonah was taught to anticipate
warning signs of potential behavior problems between
sessions and to recognize these as attempts to disrupt
the hard work of trauma processing and thus prolong
and undermine the treatment. When these impulses
occurred, Jonah over time learned to bring them to
treatment before engaging in acting-out behaviors and
explore then as potential indications that the work was
progressing too quickly or with incomplete resolution
between sessions. Thus Jonah began to take a more
active role in the titration process of treatment, and
this proactive behavior was identified and labeled as
such.
While Jonah’s feelings of anger at the perpetrator
persisted throughout this work, over time a notable
shift from desire for physical retaliation to a more
sophisticated consideration of options for justice
emerged. In addition, more vulnerable feelings of loss
around the betrayal by a trusted adult caretaker began
to surface and become incorporated into the treat-
ment. At this juncture, with the majority of trauma
targets processed, intervention with Jonah moved
toward the beginning of Phase Three of intervention:
namely, the desensitization of and preparation for
anticipated challenges to current relationships with
peers and intimate others.
Phase Three: Reconnection
The third phase of treatment resembles that of more
general psychotherapy. Unencumbered by many of the
initial after-effects of chronic trauma, attention is now
shifted out into the world of relationships. Educa-
tional and occupational endeavors, friendships and
intimate relationships, and spiritual and recreational
activities and hobbies may all develop in ways that
were previously impossible.
104
Intimacy and sexuality
often become a focus of treatment for individuals who
have experienced sexual trauma. This is frequently a
time in which patients explore connections with oth-
ers through joining clubs, reconnecting with old
friends, taking lessons, and becoming involved in
other group activities at work, church, and other set-
tings. This does not mean that traumatic material will
not be presented, but it is not the primary focus of this
phase of treatment, nor does it consume the patient’s
life or sense of self anymore.
Herman
50
notes that the “best recoveries” are seen in
patients who develop a “survivor mission.” She states
that these individuals are able to understand the social
as well as the personal dimension of their traumatic
experience(s), and transform the meaning of the
trauma by making it the basis for social action in con-
nection with others. This may take various forms,
such as volunteering in a battered women’s shelter,
becoming a mental health worker, or simply dis-
cussing one’s experience with others. At this stage
patients frequently access their creativity in ways that
were previously impossible for them, and use that cre-
ativity to address any remaining issues in relation to
the trauma. Patients have written books, produced
plays, given lectures, and created art about their trau-
matic experiences, and, more importantly, their recov-
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part Two: Treatment Luxenberg, Spinazzola, Hidalgo, Hunt, & van der Kolk
409

ery from those experiences. One can see the profound
way such activities could assist patients in altering
their previously negative or fatalistic systems of mean-
ing, as well as their sense of themselves and their feel-
ings of being powerless and helpless.
The clinician’s most vital role during this phase of
treatment is helping patients to develop their sense of
themselves as something other than a victim or even a
trauma survivor. We can think of no better way to
encapsulate this than to use the words of one of our
patients, who said to us during this stage: “Well, yes, I
was abused, but that’s not who I am! I’m a mother and
a wife and student and a runner and an artist and
someone with a great sense of humor and adventure,
and an appreciation of nature and beauty! That’s who I
am!”
Pharmacotherapy
Patients with DESNOS often present with a bewilder-
ing set of symptoms: psychobiological dysregulation
involving sleep, anxiety, abnormal arousal states, rage,
and mood disorders; biobehavioral adaptations to the
trauma; attachment problems; and dissociation. The
multiplicity of symptoms and lack of consistent diag-
nosis make it difficult to study it scientifically. There is
no published literature on the pharmacological treatment
of DESNOS. Hopefully, in the next few years
increased attention will be directed toward the need
for clinical trials in this area. In the meantime, the
burgeoning knowledge of the biology of trauma1
33
and
growing research on biological treatments for PTSD
can help to guide the pharmacological treatment of
DESNOS patients. Ultimately, however, the pharma-
cological treatment for DESNOS is for now nonspe-
cific and symptom-driven.
Before discussing target symptoms for medication
management, the following principles need to be kept
in mind when treating patients with DESNOS:
1 Pharmacotherapy is a component of a
more comprehensive treatment; one can
view pharmacotherapy as a means of
helping the patient calm down enough to
be able to make good use of therapy.
Patients need to be brought into a dis-
cussion about the role of medications in
their treatment and recovery, and learn
to use medications in conjunction with
strategies learned in their psychosocial
therapies. Given the multifaceted
nature of DESNOS, it is not uncom-
mon to see patients on a complicated
regimen of medications. A collaborative
relationship with the psychopharma-
cologist will help ensure proper use and
limit the risk of polypharmacy. Rapidly
shifting symptoms are often not occa-
sions for medication adjustments, but
opportunities for mastery and learning
how to manage and tolerate painful
emotional states using CBT, relaxation
exercises, insight, imagery, etc. Without
a good therapeutic alliance, and close
collaboration between providers, it will
be difficult to assess such developments
effectively.
2 Physicians need to pay meticulous
attention to safety. As authority figures,
doctors are likely to elicit powerful feel-
ings and behaviors of mistrust and fear,
and noncompliance in patients with
histories of abuse and neglect. This
power differential needs to be addressed
early in treatment by sharing with
patients knowledge about symptoms
and available treatment strategies.
Effectively reducing the information
gap between doctor and patient, offer-
ing options, and valuing the patient as
an expert in his or her own experience
will increase the sense of safety and
encourage the patient to take an active
role in recovery. This, however, does
not take doctors off the hook; they
must be present for their patients and
offer specific recommendations. The
strategy chosen will depend on the
specifics of the situations, the patient’s
410
Volume 21 Lesson 26Directions in Psychiatry

preference, and the doctor’s confidence
that the strategy will not be harmful to
the patient. For example, sometimes a
patient may refuse to follow a recom-
mendation for a full trial of an SSRI.
The patient may only accept a low dose
of a medication for sleep. This should
be honored, provided that the patient’s
safety is not in jeopardy. Honoring the
patient’s ability to make a choice could
lead to a strengthening of the therapeu-
tic alliance, and the possibility that the
patient may accept the recommenda-
tion in the future. Managing the sub-
tleties of the doctor–patient relation-
ship is as important as knowledge of
psychopharmacology
.134
3 Core symptoms need to be assessed
along a state-or-trait continuum.
Patients often present with acute
PTSD-like symptoms triggered by a
recent event. State-dependent reactions
often respond to a combination of tem-
porary use of medications and psy-
chosocial interventions. Long-term
pharmacologic strategies do not need to
be changed as a consequence of state-
dependent events or patients will end
up with an unnecessarily complicated
medication regimen.
4 Comorbid problems need to be actively
treated (e.g., depression, thought disor-
ders, substance abuse, etc.).
TARGET AREAS FOR
MEDICATION MANAGEMENT:
Affect Dysregulation
Patients with DESNOS often have disproportion-
ate reactions to minor stresses (affect dysregulation)
and can react to objectively neutral events as
threats or reminders of the past, which can unleash
strong emotional and behavioral responses. For
example, a slight insult may lead to rage, a minor dis-
appointment to profound sadness, or a reminder of a
threat to panic. These all-or-none emotional reactions
aggravate interpersonal and social problems. When
not overreacting, patients often shut down emo-
tionally and employ self-destructive or isolative
strategies to contain painful affects. They often
present with an inability to get along with people,
an inability to manage a job, or a feeling of being
disconnected. Obtaining a detailed history will
help to establish a specific pattern of reactions for
each individual, which can be tracked to see
whether medications are effective.
SSRIs
SSRIs are good first-line agents because of their
broad-spectrum effectiveness over a wide range of
symptoms: mood, anxiety, and impulsivity. SSRIs
have also been shown to be effective for core symp-
toms of PTSD: reexperiencing, avoidance, and
hyperarousal.
133,135,136
Our research
133
has shown that
SSRIs improve people’s capacity to observe their own
emotional reactions without necessarily acting on
them. We have postulated that this is due to increasing
the availability of serotonin in the amygdala. SSRIs are
generally well-tolerated, and have a low risk of lethal
overdose. A gradual titration is preferable. Starting at
high doses could trigger states of panic and jeopardize
compliance. For example, increasing Prozac 10 mg per
week until reaching 20 mg–40 mg, (Paxil 20 mg–40
mg, Zoloft 50 mg–150 mg.) Newer antidepressants
such as nefazodone (Serzone), venlafaxine (Effexor),
and mirtazapine (Remeron) are probably effective,
but their track record for treatment of trauma-
related symptoms is not yet established. TCAs and
MAOIs are also effective, but their side-effect profile
makes them less than desirable as first-line agents.
Ameliorating intensity of painful affects often leads to
significant changes in other areas; patients report
being able to develop better perspective, separate past
from present, and, paradoxically, develop a wider
range of affect as there is less of a need to shut down
emotions.
However, SSRIs alone will often not be enough to
contain severe symptoms. Severe states of hyper-
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part Two: Treatment Luxenberg, Spinazzola, Hidalgo, Hunt, & van der Kolk
411

412
Volume 21 Lesson 26Directions in Psychiatry
arousal, irritability, aggression, anxiety, insomnia, psy-
chotic-like symptoms, and dissociation may remain
and will require adjunctive treatment with other
classes of medications. These symptoms need to be
separated as chronic or episodic.
Treating Severe Symptoms
with Other Agents
BENZODIAZPINES:
Anxiety, irritability, and insomnia will respond to
benzodiazepines.
135
The risk of substance abuse and
the possibility of withdrawal symptoms that may
trigger more hyperarousal need to be taken into
account. A longer-acting agent such as clonazepam
(Klonopin) (0.5 mg–3.0 mg/day) should be used if it
is going to be prescribed on an ongoing basis. Tra-
zodone (Desyrel) or low-dose TCAs may also be used
adjunctively to treat insomnia. Antiadrenergic agents
such as propranolol (Inderal) (60 mg–240 mg/day) and
clonidine (Catapres, Clorpres) (0.1 mg–0.6 mg/day)
are an alternative to benzodiazepines. These agents
may improve sleep, flashbacks, nightmares, and hyper-
arousal, and can often be used temporarily as patients
work through difficult material.
135,137
MOOD STABILIZERS:
Chronic levels of irritability, aggression, and hyper-
arousal often appear to be hypomanic or manic
episodes. Mood stabilizers, such as divalproex
(Depakote), lithium, and carbamazepine (Tegretol)
have been effective with this spectrum of symp-
toms.
136–138
It is too early to tell whether the newer
mood stabilizers, such as gabapentin (Neurontin) and
topiramate (Topamax), will be as effective. Once a
mood stabilizer has been prescribed, there is often less
of a need for benzodiazepines, except for prn use (in
patients with low risk of substance abuse, benzodi-
azepines can be used as one of multiple options to deal
with acute fear and anxiety when other strategies such
as self-soothing have not worked.) Patients with
DESNOS will often require lower doses of mood sta-
bilizers than patients with bipolar disorder; for exam-
ple 250 mg–500 mg/day of Depakote.
139
ANTIPSYCHOTICS:
In our treatment of chronic trauma patients in our
outpatient clinic, we have found that the use of
antipsychotics such as risperidone (Risperdal) or
olanzapine (Zyprexa) is often helpful if the patient
presents with paranoia, a generalized thought dis-
order, or dissociative hallucinations. Antipsy-
chotics can also help reduce agitation, insomnia,
and aggressive behavior. Most DESNOS patients
receiving pharmacotherapy in our practice have
been observed to tolerate low doses of these med-
ications (Risperidone 0.5–2 mg/day, Zyprexa 1.25
mg–5 mg/day). Ideally, these patients should be
actively involved in the determination of what
dosage works best for them.
STIMULANTS:
Chronic trauma patients who suffer from attention
problems and unfocused agitation may benefit from
methylphenidate (Ritalin) or other agents that have
been proven to be helpful in the treatment of ADHD.
However, the evidence supporting this hypothesis has
been inconclusive to date in our clinical practice and
thus awaits further substantiation.
Dissociation and self-injurious behavior are difficult
to treat with pharmacological means alone, though
they often are a function of the patient’s experiencing
an uncontrollable state of hyper- or hypoarousal. Most
patients dissociate less if they learn to manage arousal
states, sometimes with the use of pharmacological
agents. Medications that decrease anxiety, such as
Clonazepam have been found to help patients gain
control over dissociative states.
61
Similarly, decreasing
temporal lobe activity with the use of anti-convulsant
medication is likely to decrease the pressure to act on
impulses to fight, flee, or freeze.
Summary
The treatment of DESNOS should be phase-oriented
and involve movement back and forth between three
basic stages: (1) stabilization; (2) trauma processing;
and (3) reintegration into the world. These phases of
treatment are useful as guidelines. It is important to
remember, however, that each patient, and each treat-

ment, is unique. The ultimate goal in the treatment of
DESNOS is to help individuals place their traumatic
experiences in the past, to access their inherent abili-
ties to experience their emotional and physical worlds
in tolerable ways, and to develop a sense of themselves
as individuals who are defined by what they think,
what they feel, who they love, the activities they enjoy,
and the values they hold, rather than by their past
traumatic experiences.
Complex Trauma and Disorders of Extreme Stress (DESNOS), Part Two: Treatment Luxenberg, Spinazzola, Hidalgo, Hunt, & van der Kolk
413
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References
Volume 21 Lesson 26Directions in Psychiatry

Questions Based On This Lesson
For more information about Hatherleigh, look up our website at www.hatherleigh.com, or give us a call at 800-367-2550.
To earn CME credits, answer the following questions on your quiz response form.
76. The recovery process in DESNOS is conceptu-
alized as entailing all of the following phases,
except:
A. Stabilization.
B. Processing and grieving of traumatic memories.
C. Constructing a plan of revenge against
victimizers.
D. Reconnection/reintegration with the world.
77. Which one of the following statements is correct?
A. In the first phase of psychological tre a t m e n t ,
stabilization, the trauma(s) should be the main
focus of therapy, not such issues as trust, safety,
self-soothing or building support network s .
B. Van der Kolk noted that trauma is often regis-
tered in the body as unspeakable terror, and
the processing of traumatic experiences can
allow individuals to put their experiences into
words, thus robbing them of their disruptive,
often somatically-based power.
C. Ex p o s u re-based treatments, such as Pro l o n g e d
Ex p o s u re, St r ess Inoculation Tra i n i n g, and C o g-
n i t i v e Processing T h e ra py a re highly effective for
P TSD, but too simplistic for the treatment of
D E S N O S .
D. Those patients who come to see a social as
well as personal dimension of their traumatic
experiences and make them the basis for
social concern and action with others are the
least likely to ever resolve their own problems
and tend to remain symptomatic for years.
78. Which one of the following statements is corre c t ?
A. DESNOS patients treated with antidepres-
sants alone are much more likely to improve
and stay well than those who receive any kind
of psychological therapy, with or without
medication.
B. If at all possible, it is best never to give any
p s ychopharmacologic agents to DESNOS
patients because this is so often misinterpre t e d
by them as another form of victimization.
C. The medications which have been most
extensively studied and found highly effective
in DESNOS are stimulants like methyl-
phenidate.
D. Extrapolating from medication studies in
patients with PTSD, the SSRIs appear to be
the most desirable agents to use to manage
affect dysregulation, reexperiencing, avo i d a n c e ,
h y p e r a rousal, and depression in DESNOS
p a t i e n t s .