Case report of a sarcoma botryoides of the uterine cervix in fertile age and literature review
Department of Obstetrics and Gynecology, Second University of Naples, Via Palasciano, AORN Sant'Anna e S. Sebastiano, 81100 Caserta, Italy. Archives of Gynecology
(Impact Factor: 1.36).
04/2009; 280(5):863-6. DOI: 10.1007/s00404-009-1022-3
The sarcoma botryoides of the cervix uteri occurs very rarely in fertile women.
Here is a case of a 35-year-old fertile woman, who developed a sarcoma botryoides of the cervix uteri. The diagnosis required clinical examination, ecography, NMR, CT scan and a pathological examination of the surgical sample. Radical surgery and chemotherapy was performed. The patients is still living after more than 1 year after treatment.
Although the combined modality approach has given, if not constant, acceptable outcomes, a larger investigation on all the cases of sarcoma botryoides of the cervix uteri is expected.
Available from: Elif Meseci
- "At this localization, the tumor arises from the cervical mucosal epithelium or the middle tunica, and usually appears as a cervical polyp protruding out the external orifice. The tumor has a fast growth pattern, mainly spreading to the lungs and liver by blood circulation . The etiology and specific risk factors are not known . "
Available from: Glauco Baiocchi
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ABSTRACT: Embryonal rhabdomyosarcoma (RMS) of the female genital tract usually occurs in the vagina during childhood. The uterine cervix as a primary site is rare, but is more frequent until the second decade of life. It usually has a good prognosis and the treatment is based on multidrug chemotherapy, radiotherapy and surgery. RMS accounts for <5% of all adult soft tissue sarcomas. Previous reports that included all primary sites showed a poorer five-year disease specific survival for adults with RMS when compared to the pediatric population. This difference has been attributed to a higher proportion of adverse prognostic clinical and pathological factors, and to inadequate treatment given to adults with RMS. A total of 115 patients with cervical embryonal RMS have previously been described; however, only 10 cases were reported in women older than 40 years. We present a 47-year-old woman treated with radical hysterectomy followed by adjuvant chemotherapy and review the current literature.
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ABSTRACT: Embryonal rhabdomyosarcoma in a form of a polyp of the uterine cervix occurs mainly in young women in their second decade of life. The characteristic microscopic features are: the submucosal cambium layer and the presence of rhabdomyoblasts in the stroma. So far the treatment has not been well defined and ranges from conservative to radical surgery
The presented case is a 22-year old woman with cervical polyp. Polypectomy with D&C was performed in 2005 and the microscopic examination revealed rhabdomyosarcoma botryoides. Detailed examination diagnosed stage 1a of the disease. The patient received 6 cycles of chemotherapy (Vincristine and Actinomycin).
Conservative treatment may be considered in young women with favorable prognostic factors who wish to preserve their fertility Polypectomy followed by chemotherapy is a possible option for such patients.
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