by plain films may not translate into patient important
benefit. Nevertheless, low intensity pulsed ultrasono-
graphy may provide important benefits to patients with
fracture through accelerated improvement in function.
Large trials of high methodological quality focusing on
patient important outcomes such as quality of life and
return to function are needed to establish whether this
is the case.
We thank Wolfram Bosenberg for translating web reference 3. JWB is
funded by a new invest igator award from t he Ca nadian Institutes of Health
Research a nd Canadian Chiropractic Research Foundation. MB is
supported in part by a Canada research chair, McMaster U niversity. HJS is
funded by a European Commissio n: the human factor, mo bility and Marie
Curie Actions, scie ntist reintegration grant (IGR 42192).
concept.JWB, JK, and BM collected the data. JWB and GHG did the analysis.
All authors critically revised the manuscript and approved the fina l version.
JWB is the guarantor.
Competi ng interests: JWB, MB, and GHG are currently involved in a
multicentre, randomised controll ed trial that has received pa rtial funding
from Smith and Nephew, the company that manufactures Exogen. GHG
and HJS are members of the GRADE working group.
Ethical approval: Not required.
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