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Journal of Biosafety & Health Education
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Journal of Biosafety & Health Education
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Digital Object Identier: http://dx.doi.org/10.4172/jbhe.1000e108
Volume 1 • Issue 3 • 1000e108
J Biosafety Health Educ
ISSN: JBHE an open access journal
Editorial
Open Access
Biosafety & Health Education
Mondal, J Biosafety Health Educ 2013, 1:3
http://dx.doi.org/10.4172/jbhe.1000e108
Children are the source of hope and inspiration for the society. at
is why they have the right to be brought up in a positive environment.
But there are many children in the world who have become synonymous
with social deprivation at its worst. Children who are working and living
on the streets are found throughout the nation. Street children constitute
a marginalized population in most urban centers of the world. ere are
major diculties in trying to estimate the number of street children
and the magnitude of hardship they experience. In their marginalized
state they constitute a truly “hidden” population who were not covered
by nor nd place in the national census, educational or health data,
largely because they have no xed address [1]. is problem is further
compounded by the fact that they are also a highly mobile population.
However, it is speculated that between 100,000 and 125,000 children
live on the streets and railway stations of India’s major cities, and that
more than half of them have some form of drug addiction.
Street boys living at dierent Indian railway stations of West
Bengal, take care of themselves and each other in an otherwise uncaring
environment and surviving through begging, petty the or hawking
goods on the platforms. Most of the paltry sum they earn is spent on
tobacco or on tube of Glue (locally known as ‘Dendrite’ which is an
industrial contact adhesive and rubber cement brand marketed as
glue sticks, tubes and cans in India and South Asia, mainly in Eastern
India, Bangladesh and Bhutan) that is a particular favorite with those
children. is golden colored industrial glue (oen called as ‘golden
glue’) containing organic solvents is cheap and readily available and
provides faster onset of action and the regular ‘high’ [2,3]. Investigators
believe that the addicts can be exposed to several thousand parts per
million (2,000-30,000 ppm) of organic solvents within a few minutes
[4]. e kids squeeze Glue onto a rag and hu its fumes through the
mouth.
Although these products are not classied as drugs because they
are not intended to be used to achieve intoxication, young children and
adolescents can easily obtain them and are among those most likely
to abuse them [5]. Besides addiction, they’re usually victims of abuse
and harassment, and are extremely vulnerable to tracking, sex trade
and child labor [6]. Inhalant abuse/dependence has been reported from
various parts of the world [7-10]. Drug usage among minors has created
a global generation of addicted and oen abandoned children bere of
family support, education and social skills. ere are epidemiological
reports indicating that chronic exposure to abuse solvents can produce
loss of appetite [5]; however, the mechanisms involved in these eects
are not well understood. It’s sad that kids would come to that.
Our previous reports suggested that tobacco smoking and/or
chewing habit among street boys is associated with increased frequency
of micronucleus and γ-H2AX foci formation in oral mucosa, implying
chromosomal and DNA damage respectively [11]. Additional habit of
sning/hung of industrial glue enhances the severity of genotoxic
changes in buccal epithelial cells of these children. We also observed
marked increase in argyrophilic nuclear organizer region (AgNOR)
in buccal epithelial cells of glue-addicted children, suggesting up-
regulation of ribosome biogenesis in these cells [12]. Taken together,
these studies indicate genetic changes in oral mucosa of street boys
in association with tobacco and glue sning or hung habit. So it
is necessary to campaign biosafety and health education programme
explaining the adverse health eects of inhalant abuse by the young
futures throughout the nation. Genetic markers could provide a useful
means of detecting early mutagenic events for assessing cancer risk
associated with inhalant abuse which is quite prevalent in developed
countries also. In the United States, for example, nearly 20% of young
persons have experimented with inhalants at least once by the time they
are in eighth grade and the mean age of rst-time inhalant abuse is
13 years [13]. More importantly, children who abuse inhalants early in
life are more likely later to use other illicit drugs. us inhalant abuse
intervention programs seem important from the community health
perspective also.
References
1. Benegal V, Bhushan K, Seshadri S, Karott M (1998) Drug Abuse Among Street
Children in Bangalore. Monograph Funded by CRY.
2. Basu D, Jhirwal OP, Singh J, Kumar S, Mattoo SK (2004) Inhalant abuse by
adolescents: a new challenge for Indian physicians. Indian J Med Sci 58: 245-
249.
3. Seth R, Kotwal A, Ganguly KK (2005) Street and working children in Delhi,
India, misusing toluene: an ethnographic exploration. Subst Use Misuse 40:
1659-1679.
4. Marjot R, McLeod AA (1989) Chronic non-neurological toxicity from volatile
substance abuse. Hum Toxicol 8: 301-306.
5. Inhalants (2004) National Institute on Drug Abuse, National Institutes of Health,
U.S. Department of Health & Human Services.
6. Gupta SK, Bali S, Jiloha RC (2009) Inhalant abuse: an overlooked problem.
Indian J Psychiatry 51: 160-161.
7. Weir E (2001) Inhalant use and addiction in Canada. CMAJ 164: 397.
8. Ramon MF, Ballesteros S, Martinez-Arrieta R, Torrecilla JM, Cabrera J (2003)
Volatile substance and other drug abuse inhalation in Spain. J Toxicol Clin
Toxicol 41: 931-936.
9. Thiesen FV, Barros HM (2004) Measuring inhalant abuse among homeless
youth in southern Brazil. J Psychoact Drugs 36: 201-205.
*Corresponding author: Nandan Kumar Mondal, Articial Organ Laboratory,
Department of Surgery, University of Maryland School of Medicine, 10 South Pine
Street, Baltimore, Maryland 21201, USA, Tel: 410-706-4549; Fax: 410-706-0311;
E-mail: nkmondal@smail.umaryland.edu
Received
May 12, 2013; Accepted May 16, 2013; Published May 18, 2013
Citation: Mondal NK (2013) Commercial Glue Snifng and Child Health: Indian
Street Children are at a Risk. J Biosafety Health Educ 1: e108. doi:10.4172/
jbhe.1000e108
Copyright: © 2013 Mondal NK. This is an open-access article distributed under
the terms of the Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the original author and
source are credited.
Commercial Glue Sniffing and Child Health: Indian Street Children are at a
Risk
Nandan Kumar Mondal*
Articial Organ Laboratory, Department of Surgery, University of Maryland School of Medicine, USA
Page 2 of 2
J Biosafety Health Educ
ISSN: JBHE an open access journal
10. Wu LT, Pilowsky DJ, Schlenger WE (2004) Inhalant abuse and dependence
among adolescents in the United States. J Am Acad Child Adolesc Psychiatry
43: 1206-1214.
11. Mondal NK, Ghosh S, Ray MR (2011) Micronucleus formation and DNA
damage in buccal epithelial cells of Indian street boys addicted to gasp ‘Golden
glue’. Mutat Res 721: 178-183.
12. Mondal NK, Ghosh S, Ray MR (2011) Quantitative analysis of AgNOR proteins
in buccal epithelial cells of Indian street boys addicted to gasp ‘golden glue’.
Exp Toxicol Pathol 63: 677-681.
13. McGarvey EL, Clavet GJ, Mason W, Waite D (1999) Adolescent inhalant abuse:
environments of use. Am J Drug Alcohol Abuse 25: 731-741.
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Citation: Mondal NK (2013) Commercial Glue Snifng and Child Health: Indian Street Children are at a Risk. J Biosafety Health Educ 1: e108.
doi:10.4172/jbhe.1000e108
Volume 1 • Issue 3 • 1000e108
Citation: Mondal NK (2013) Commercial Glue Snifng and Child Health: Indian
Street Children are at a Risk. J Biosafety Health Educ 1: e108. doi:10.4172/
jbhe.1000e108