There is a significant financing gap for businesses seeking between $US250 000 and $US2 million. Filling this gap are the approximately 400 000 business angels scattered across the country who invest approximately $US30-40 billion a year in 50 000 early stage businesses. Increasingly angels are investing together in groups. Angel Healthcare Investors (AHI), LLC is one such angel group comprising investors with backgrounds in the healthcare sector who invest in innovative business start-ups in various healthcare markets. The paper describes AHI's operations, yield rates and portfolio firms. It concludes with a view of current trends in angel investing.