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Science against microbial pathogens: photodynamic therapy approaches.
Abstract and Figures
There is an emerging area of research to identify the application of photodynamic therapy (PDT) as a means to kill microbial pathogens. In fact, the first recorded observation in more than 100 years ago of photodynamic processes was inactivation of microorganism. In this volume of the Formatex Microbiology book titled: Science against microbial pathogens: communicating current research and technological advances, this chapter will focus on the use of photosensitizer and light as anti-microbial agent against various microbes in different settings. The mechanism of action of PDT inactivating microorganisms, anti-microbial photosensitizing agents and light sources used for eliminating microorganisms will be covered. The success and challenges of using PDT to eradicate bacteria including antibiotic resistant bacteria will be discussed. Free full-text is available at http://www.formatex.info/microbiology3/book/668-674.pdf
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