Green tea catechin plus caffeine supplementation to a high-protein diet has no additional effect on body weight maintenance after weight loss

ArticleinAmerican Journal of Clinical Nutrition 89(3):822-30 · June 2009with21 Reads
DOI: 10.3945/ajcn.2008.27043 · Source: PubMed
Abstract
Green tea (epigallocatechin gallate + caffeine) and protein each were shown to improve body weight maintenance after weight loss. We investigated the effect of a green tea-caffeine mixture added to a high-protein (HP) diet on weight maintenance (WM) after body weight loss in moderately obese subjects. A randomized, placebo-controlled, double-blind parallel trial was conducted in 80 overweight and moderately obese subjects [age (mean +/- SD): 44 +/- 2 y; body mass index (BMI; in kg/m(2)): 29.6 +/- 2.0] matched for sex, age, BMI, height, body mass, and with a habitually low caffeine intake. A very-low-energy diet intervention during 4 wk was followed by 3 mo of WM; during the WM period, the subjects received a green tea-caffeine mixture (270 mg epigallocatechin gallate + 150 mg caffeine/d) or placebo, both in addition to an adequate protein (AP) diet (50-60 g protein/d) or an HP diet (100-120 g protein/d). Subjects lost 7.0 +/- 1.6 kg, or 8.2 +/- 2.0%, body weight (P < 0.001). During the WM phase, WM, resting energy expenditure, and fat-free mass (FFM) increased relatively in both the HP groups and in the AP + green tea-caffeine mixture group (P < 0.05), whereas respiratory quotient and body fat mass decreased, all compared with the AP + placebo group. Satiety increased only in both HP groups (P < 0.05). The green tea-caffeine mixture was only effective with the AP diet. The green tea-caffeine mixture, as well as the HP diet, improved WM independently through thermogenesis, fat oxidation, sparing FFM, and, for the HP diet, satiety; a possible synergistic effect failed to appear.
    • "For instance, protein intake interferes with effects of green tea catechin caffeine mixtures in acute242526272829 as well as long term studies [30, 31]. A green tea catechin caffeine intake does not add synergistically to the beneficial effect of a high-protein diet during weight maintenance after weight loss, while protein intake alone as well as consumption of the green tea mixture showed beneficial effects based upon preservation of fat free body mass and sustained energy expenditure despite being in negative energy balance [30]. The inhibitory effect of protein, especially proline-rich caseins, on the effect of green tea catechins due to the formation of protein-polyphenol complexes that reduce the absorption or that produce metabolites without thermogenic actions313233343536 may cause this phenomenon. "
    [Show abstract] [Hide abstract] ABSTRACT: Green tea catechins mixed with caffeine have been proposed as adjuvants for maintaining or enhancing energy expenditure and for increasing fat oxidation, in the context of prevention and treatment of obesity. These catechins-caffeine mixtures seem to counteract the decrease in metabolic rate that occurs during weight loss. Their effects are of particular importance during weight maintenance after weight loss. Other metabolic targets may be fat absorption and the gut microbiota composition, but these effects still need further investigation in combination with weight loss. Limitations for the effects of green tea catechins are moderating factors such as genetic predisposition related to COMT-activity, habitual caffeine intake, and ingestion combined with dietary protein.
    Full-text · Article · Feb 2016
    • "All studies had test period for at least 12-13 weeks except for Tsuchida T et al. [21] that had a test period of 8 weeks. Two WM studies [14, 20] had participants with first weight loss phase for 4 weeks using a very low energy diet, followed by randomization and then an EGCG–caffeine mixture supplementation phase for either 12 or 13 weeks. One study [16] randomly assigned subjects to three different dosage conditions as compared to controls. "
    [Show abstract] [Hide abstract] ABSTRACT: Obesity is the growing health disorder globally and lifestyle changes are at the heart of this problem. It has been found that green tea market is increasing. One of the supposedly many effects of green tea is the weight loss. There is vast literature available related to this subject. The purpose of this study was to elucidate by meta-analysis whether green tea has an effect on body weight. PubMed search was done for the term - Green tea and later limited by English-language, human studies published in last decade and available as full text. Out of the 704 initially retrieved articles 11 were included in the present meta-analysis after considering the exclusion and inclusion criteria of the study. The pooled results of all the studies with the random effect model is -1.26 [-1.87 to -0.65]. It is imperative by this meta-analysis that green tea consumption leads to weight loss. However the substantial heterogeneity (I2 = 81.71%) among the studies warranties larger studies for confirmation and validation of the effect of green tea on weight of an individual.
    Article · Jul 2015 · PLoS ONE
    • "Athletic, healthy women may want to reduce their body weight for personal or professional reasons, such as to achieve a specific weight class or to improve athletic performance through changes in body composition. Caloric restriction through low-calorie diets and very low-calorie diets has been used for rapid weight loss for decades, and the literature supports their effective- ness12345. However, the duration of the low-calorie interventions in these studies varies from 1–3 months, and no studies have investigated rapid weight loss with an intervention lasting less than 1 month, which may be necessary in certain weight class sports. "
    [Show abstract] [Hide abstract] ABSTRACT: Weight loss benefits of multi-ingredient supplements in conjunction with a low-calorie, highprotein diet in young women are unknown. Therefore, the purpose of this study was to investigate the effects of a three-week low-calorie diet with and without supplementation on body composition. Methods Thirty-seven recreationally-trained women (n = 37; age = 27.1 ± 4.2; height = 165.1 ± 6.4; weight = 68.5 ± 10.1; BMI = 25.1 ± 3.4) completed one of the following three-week interventions: no change in diet (CON); a high-protein, low-calorie diet supplemented with a thermogenic, conjugated linoleic acid (CLA), a protein gel, and a multi-vitamin (SUP); or the highprotein diet with isocaloric placebo supplements (PLA). Before and after the three-week intervention, body weight, %Fat via dual X-ray absorptiometry (DXA), segmental fat mass via DXA, %Fat via skinfolds, and skinfold thicknesses at seven sites were measured. Results SUP and PLA significantly decreased body weight (SUP: PRE, 70.47 ± 8.01 kg to POST, 67.51 ± 8.10 kg; PLA: PRE, 67.88 ± 12.28 kg vs. POST, 66.38 ± 11.94 kg; p 0.05) with a greater (p ≤ 0.05) decrease in SUP than PLA or CON. SUP and PLA significantly decreased %Fat according to DXA (SUP: PRE, 34.98 ± 7.05% to POST, 32.99 ± 6.89%; PLA: PRE, 34.22 ± 6.36% vs. POST, 32.69 ± 5.84%; p ≤ 0.05), whereas only SUP significantly decreased% Fat according to skinfolds (SUP: PRE, 27.40 ± 4.09% to POST, 24.08 ± 4.31%;p ≤ 0.05). SUP significantly (p ≤ 0.05) decreased thicknesses at five skinfolds (chest, waist, hip, subscapular, and tricep) compared to PLA, but not at two skinfolds (axilla and thigh). Conclusions The addition of a thermogenic, CLA, protein, and a multi-vitamin to a three-week low-calorie diet improved weight loss, total fat loss and subcutaneous fat loss, compared to diet alone.
    Full-text · Article · Apr 2015
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