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The Impact of Universal Health Insurance on Catastrophic and Out-of-Pocket Health Expenditures in Mexico: a Model with an Endogoenous Treatment Variable

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Abstract

The main goal of Seguro Popular is to improve the financial protection of the uninsured population against excessive health expenditures. Seguro Popular (SP) covers a variety of preventive and curative procedures, as well as medicines, and hospital care for the poorest segment of the Mexican population. Data: This paper estimates the impact of Seguro Popular on catastrophic health expenditures, as well as out-of-pocket health expenditures, from three different sources: National Household Survey of Income and Expenditures (ENIGH 2006); National Health and Nutrition Survey (ENSANUT 2006); and SP Impact Evaluation Survey. Methods: We first estimate naive probit models, and then compare them against bivariate probit models which use instrumental variables that take advantage of the specific SP implementation mechanisms to address the endogeneity of insurance selection choices. Results: No effect on catastrophic health expenditures is observed in the ENIGH sample. However, we find a statistically significant effect on the reduction of household’s expenditures on medicines and outpatient care. On the other hand, Seguro Popular reduces the probability of catastrophic health expenditures using the other two datasets: SP Impact Evaluation Survey, and ENSANUT. We also observe a reduction of the probability of expenditures on medicines and outpatient care among the SP insured families.
HEDG Working Paper 08/12
THE IMPACT OF UNIVERSAL HEALTH INSURANCE ON
CATASTROPHIC AND
OUT-OF-POCKET HEALTH EXPENDITURES IN MEXICO:
A MODEL WITH AN ENDOGENEOUS TREATMENT
VARIABLE
Omar Galárraga
Sandra G. Sosa-Rubí
Aarón Salinas
Sergio Sesma
June 2008
ISSN 1751-1976
http://www.york.ac.uk/res/herc/research/hedg/wp.htm
THE IMPACT OF UNIVERSAL HEALTH INSURANCE ON
CATASTROPHIC AND
OUT-OF-POCKET HEALTH EXPENDITURES IN MEXICO:
A MODEL WITH AN ENDOGENEOUS TREATMENT VARIABLE
Omar Galárraga1,2, Sandra G. Sosa-Rubí1, Aarón Salinas1, Sergio Sesma3
For Submission to:
17th European Workshop on Econometrics and Health Economics
1 June 2008
From the:
1 National Institute of Public Health (INSP), Cuernavaca, Mexico
2 Institute of Business and Economic Research (IBER), University of California, Berkeley, CA.
3 Carso Institute for Health, Mexico City, Mexico.
Correspondence to: Sandra G. Sosa-Rubí, Health Economics Unit, Center for Evaluation and Survey
Research, National Institute of Public Health (INSP), Av. Universidad 655, Cuernavaca, C.P. 62508,
Mexico. E-mail: srubi@insp.mx
2
SUMMARY
Introduction: The main goal of Seguro Popular is to improve the financial protection
of the uninsured population against excessive health expenditures. Seguro Popular (SP)
covers a variety of preventive and curative procedures, as well as medicines, and
hospital care for the poorest segment of the Mexican population.
Data: This paper estimates the impact of Seguro Popular on catastrophic health
expenditures, as well as out-of-pocket health expenditures, from three different sources:
National Household Survey of Income and Expenditures (ENIGH 2006); National
Health and Nutrition Survey (ENSANUT 2006); and SP Impact Evaluation Survey.
Methods: We first estimate naive probit models, and then compare them against
bivariate probit models which use instrumental variables that take advantage of the
specific SP implementation mechanisms to address the endogeneity of insurance
selection choices.
Results: No effect on catastrophic health expenditures is observed in the ENIGH
sample. However, we find a statistically significant effect on the reduction of
household’s expenditures on medicines and outpatient care. On the other hand, Seguro
Popular reduces the probability of catastrophic health expenditures using the other two
datasets: SP Impact Evaluation Survey, and ENSANUT. We also observe a reduction
of the probability of expenditures on medicines and outpatient care among the SP
insured families.
AEA-JEL classification: 012, 038, 054, I18, I38
Key terms: catastrophic health expenditures; health insurance; instrumental variables;
non-linear methods; Mexico
3
1. INTRODUCTION
This paper has two main goals. First, we provide estimates of the treatment effect of
universal health insurance targeted to the poorest families on catastrophic health
expenditures in Mexico using three different data sources. Second, we compare the
results and survey methodologies, and try to explain some of the differences
encountered in the estimation of the treatment effect. We draw on previous analyses of
the issues around catastrophic health expenditures in Mexico (Parker and Wong 1997;
Perez-Rico, Sesma-Vazquez et al. 2005; Sesma-Vazquez, Perez-Rico et al. 2005;
Gakidou, Lozano et al. 2006; Knaul, Arreola-Ornelas et al. 2006), but we add a new
dimension in the literature by using non-linear models with selection correction for the
potentially endogenous treatment variable. To the best of our knowledge, this paper
provides the first non-experimental evidence of a causal effect of Seguro Popular on
catastrophic health expenditures. Previous analyses using non-experimental data
demonstrated strong associations but have not used methods to show causal effects.
The results presented here are relevant in the Mexican context, but they go beyond that.
The issue of the impact of universal health insurance on financial protection is of wide
relevance across Latin America and other regions.
This paper proceeds as follows. In Section 2 we present a brief background of the
Seguro Popular program in Mexico. Section 3 shows the methods used including data
sources and study population. Section 4 presents the results, followed by a discussion.
The paper ends with some conclusions for policy and future research.
4
2. BACKGROUND
The Popular Health Insurance (or “Seguro Popular”) was implemented in Mexico as a
comprehensive health reform effort to provide financial protection in health for the
poorest segment of the population (Frenk, Gonzalez-Pier et al. 2006). Until 2001 health
insurance coverage in Mexico was directed only to employees working in the formal
sector of the economy. Coverage for formal sector workers included the Mexican
Social Insurance System (Instituto Mexicano del Seguro Social, or IMSS), the
Government Workers’ Social Security and Services Institute (Instituto de Seguridad y
Servicios Sociales de los Trabajadores del Estado, or ISSSTE), as well as insurance
programs for employees of such state-run enterprises as PEMEX (petroleum) and
SEDENA (national defence). Participants in the informal sector of the economy had to
attend government-sponsored facilities through the Ministry Health (Secretaría de
Salud, or SSA) or pay out-of-pocket for medical care at private health services. These
private facilities varied considerably in price, quality, and availability. Whilst a modern
network of private health services for the middle and upper classes served those
individuals who had insurance coverage or could pay out-of-pocket (OOP) for their
health care, there was also a lower-priced private health providers of variable quality.
By 2002 there was evidence of excessive health-related spending for the poorest rural
families in Mexico, particularly for the care of older adults (over 60 years of age) and
the care of pregnancy (Torres and Knaul 2003; Knaul, Arreola-Ornelas et al. 2005;
Sesma-Vazquez, Perez-Rico et al. 2005). Most of the catastrophic expenditures among
the poor were attributed to outpatient care and medications. This situation is common
among the poorest segments of the population in most developing countries where “a
relatively small payment can mean financial catastrophe to a poor person or household,
forcing them to reduce other basic expenses such as food, shelter, or their children’s
5
education” (Xu, Evans et al. 2007), or even suffer financial catastrophe (Van Damme,
Van Leemput et al. 2004).
The explicit goal of the Seguro Popular program was to financially protect the poorest
families (within the poorest two income deciles) that did not have any health insurance
coverage. Although the campaigns to be enrolled were targeted to the poorest sections
of the population in rural an urban areas, the decision of enrolling to SP was a family’s
voluntary choice (Frenk, Gonzalez-Pier et al. 2006). The program objectives were to
assure:
(i) the protection of poor families against catastrophic health
expenditures and its impoverishing effect; and
(ii) the universal access to adequate secondary and tertiary medical care.
Additionally, on the supply-side, all SP-sponsored health facilities from the public
health providers had to offer a minimum level of health-services quality in order to
belong to the SP-sponsored health facilities network.
The process of health unit accreditation to Seguro Popular was rolled out gradually
during 2001–2005. Five states (Aguascalientes, Campeche, Colima, Jalisco and
Tabasco) were incorporated into the program in 2001 as part of a pilot study. An
additional 15 states were integrated in the program in 2002; four more states were
incorporated in 2003; and the remaining states were incorporated in during 2004 and
2005. By the end of 2005, all 32 of Mexico’s states had been incorporated, and
approximately 4 million families (comprising about 12 million individuals) had signed
up for the voluntary program (SSA 2006a).
6
Overall, through the first quarter of 2007, approximately 5.2 million (44 %) of the
estimated 11.9 million eligible households nationwide had enrolled in the program.
Although the indicators of coverage have widely shown the proven capacity of the SP
programme to enrol a large group of uninsured households, there has been limited
evidence about the medium-term improvements in the financial protection of the
poorest households.
Analyses about the trends and evolution of catastrophic and impoverishing health
spending have shown a decreased incidence of catastrophic spending among the poorest
households, but this trend was not clearly found in the case of the out-of-pocket
expenditures (Knaul, Arreola-Ornelas et al. 2005).
There have been only few studies that have empirically estimated the effect of the health
insurance coverage on the incidence of catastrophic health spending in developing
countries with experimental data (Wagstaff and Yu 2007), and fewer with observational
data (Jowett, Contoyannis et al. 2003).
3. METHODS
3.1 Data Sources and Study Population
We analysed the impact of Seguro Popular on the incidence of catastrophic health
expenditures and out-of-pocket health expenditures among poor households using three
different data sources of household expenditure and insurance enrolment. We used data
from:
7
Encuesta Nacional de Ingreso y Gasto de los Hogares (ENIGH 2006) [National
Household Survey of Income and Expenditures]; and
Encuesta Nacional de Salud y Nutrición (ENSANUT 2005-2006) [National
Health and Nutrition Survey].
Encuesta de Impacto del Seguro Popular [SP Impact Evaluation Survey];
For all surveys, we had strict selection criteria such that we identified households where
all members of the household were enrolled into Seguro Popular (“insured” group); that
is, our “treatment” is that everyone in the household be officially enrolled into the SP
program. Then, we created a comparison group of households with no insurance
coverage at all (“uninsured” group); that is, our controls are households where no
person had any type of health insurance.
The ENIGH 2006 is a cross-sectional dataset with nationally representative data, with a
sample of 20,875 dwellings (INEGI 2006). Its main purpose was to obtain information
about income and expenses of the households. It collected information about
occupational characteristics, socio-demographic characteristics of the members of the
households, infrastructure characteristics of the dwellings and household assets. It also
has information about the access to public programmes by households (including
transfers and subsidies). From the original sample with health expenditure data and
health insurance data, we selected 1,736 SP-insured households and 12,936 uninsured
households.
The ENSANUT 2006 is also a cross-sectional dataset with nationally representative
data, which was collected for 48,304 dwellings (INSP 2006). This dataset contains
8
information about individual’s health, use of health services, socio-economic
characteristics of households, access to health programmes, and biological health
indicators. From the original sample, we took those 45,699 households with health
expenditure data and health insurance data. After this, we end up with the analytical
samples: 4,440 SP-insured households and 16,376 uninsured households.
The SP Impact Evaluation Survey is a panel dataset composed with 36,000 dwellings
for which there was baseline information (August 2005) in 32,506 dwellings, and first-
wave of data collected in mid-2006 with information in 29,836 dwellings (King and et
al 2006; SSA 2006b; King, Gakidou et al. 2007). The data were collected in seven states
in Mexico (Sonora, San Luis Potosi, Jalisco, Estado de Mexico, Guerrero, Morelos and
Oaxaca). Its main purpose was to measure the impact of Seguro Popular among eligible
households (poor households without any coverage of health insurance). The criteria to
select the location of the treatment and control clusters were: i) to include those zones
were the rate of penetration of the programme was very low; ii) to include those places
where the incorporation of the SP programme was being postponed. Note that this data
was experimental in design with a baseline and follow-up rounds of data collection.
However, we are using only the follow-up data, as if it was a cross-section, so that we
can maximize the comparability with the other two data sources. (Details on the
experimental design have been presented elsewhere (King, Gakidou et al. 2007)). From
the 29,836 households with the relevant data (in the first-wave of data follow-up), we
selected the following analytical samples: 7,952 SP-insured households and 21,884
uninsured households.
9
3.2 Variables and Analysis
Based on the literature, the basic econometric specification we used to analyze the
impact of health insurance on catastrophic health expenditures (CHE) was of the form:
Y = X + T + + e1 (1)
T = X + + Z + e2 (2)
where:
Y = catastrophic health expenditure
X = covariate vector
T = household enrolment into Seguro Popular
Z= instrumental variables
We defined expenditure as being catastrophic with a dummy variable equal to the unity
if a household's financial contributions to the health system exceed 30% of income
remaining after subsistence needs ($2 USD per capita) have been met; and zero
otherwise. This definition is the most widely used in the literature (Murray, Knaul et al.
2000; Xu, Klavus et al. 2003), but there are other alternatives (Xu, Evans et al. 2003)4.
In the naïve probit models, we assumed that the error terms e1 and e2 were not correlated,
and thus we could directly estimate equation (1), independently of equation (2).
However, considering a potentially endogenous treatment variable, we also used a model
with a bivariate normal distribution for the error terms (Maddala 1994; Wooldridge 2002;
Greene 2003), with the variance normalized to the unity and the correlation coefficient
denoted as , in the following manner:
4 Other criteria that have been used to define catastrophic expenditures is when the household’s financial
contributions to the health system exceed 40% of income and subsistence needs of $1 USD per capita).
10
1
1
,
0
0
~
2
1
ρ
ρ
BVN
e
e (3)
The correlation between e1 and e2 captures the correlation between the likelihood of
having catastrophic health expenditures, and at the same time having enrolled in Seguro
Popular. We hypothesized that >0 because those households which may be more
prone to have high health care expenditures (relative to the level of household income),
would also have more incentives to sign up for Seguro Popular.
To select an appropriate covariate vector we searched the literature (Makinen, Waters et
al. 2000; Kawabata, Xu et al. 2002; Xu, Evans et al. 2003) and found that the main
determinants of CHE seem to relate to poverty, aging, chronic illnesses, low levels of
insurance coverage, urban/rural differences, socio-economic status, types of illnesses,
demographic composition of the household, and characteristics of the household head
(age, sex, education). Health spending would be affected by the family’s
wealth/physical assets, its income or financial assets as well as their insurance coverage.
We have used an asset index as a proxy for household wealth (McKenzie 2004).
Additionally, we have used the deprivation index at the municipality/locality level to
control for general levels of wellbeing at the local level (CONAPO 2005).
Thus, the main explanatory or “treatment” variable (T) to be analysed was enrolment
into Seguro Popular (SP), a public insurance scheme for the poor and otherwise
uncovered population in Mexico. Enrolment into Seguro Popular would be determined
by equation (2) above, which has the same covariate vector X, and a set of instrumental
variables (Z). These set of “instruments” would strongly affect the probability of a
household being part of the SP program, but they would not be correlated with the
11
outcome of interest (catastrophic expenditures in health) through channels other than the
enrolment into SP. The instrumental variables approach has been used in several
studies of CHE (Pradhan and Prescott 2002; Jowett, Contoyannis et al. 2003; Jowett,
Deolalikar et al. 2004; Sepehri, Sarma et al. 2006)
The instrumental variables we used take advantage of the fact that Seguro Popular was
implemented gradually across the different 32 Mexican states. First, we used the year
of incorporation as a proxy for the length of time that a particular state has had Seguro
Popular. For example, if a state was incorporated by 2003, a dummy variable for 2001
would be zero, a dummy for 2002 would also be zero, but the dummy variables for
2003 and 2004 would be equal to the unity. By 2005 all states were incorporated, so
that 2005 serves as the reference year (except in the SP Impact Survey where the
reference year was 2002). The marginal effect of the incorporation dummy measures
the effect incorporation a year earlier on the household SP enrolment probability. This
instrument has been implemented successfully in a similar context (Sosa-Rubi,
Galarraga et al. 2007).
We recognize that the official dates of incorporation (SSA 2006b) may not be
necessarily exact indicators of program availability, because some health centres may
still have been going through accreditation by the end of the year. Thus, we view these
instruments as indicators of likelihood that SP was available to each household in the
survey. This use of year-of-incorporation dummies as instruments follows the spirit of
Duflo’s use of distance from schools as instruments a study of impact of school
construction on educational attainment and wages in Indonesia (Duflo 2001).
12
Second, similar to the first set of instrumental variables, we used the level of penetration
of the program at the locality level to help us determine the probability of enrolment.
The logic was that households living in localities with higher SP penetration or
coverage had higher probabilities of enrolling into the program. We constructed the
variable with a ratio of SP enrolled households over eligible (uninsured households) at
the locality level using the latest round of Census data (INEGI 2005). Households
located in areas where the level of diffusion of Seguro Popular was higher tended to
have higher probability of being enrolled into the SP program. We see this instrumental
variable as an aggregate continuous proxy for program participation at the household
level. We are implicitly assuming that the level of program diffusion or penetration has
a direct impact on the behavioural choices of households; but assuming that there is no
underlying aggregate effect over expenditures, other than through the channel of
insurance choice (Angrist, Imbens et al. 1996; Heckman 1997; Angrist and Krueger
2001).
The regional and temporal variations in incorporation and coverage rates helped us to
identify Seguro Popular household enrolment, independently of the outcomes of
interest: catastrophic health expenditures. Thus, the year-of-incorporation dummies as
well as SP coverage rates (as a continuous variable: 0-100%) were excluded from the
equation (1).
We have encountered no evidence of “policy endogeneity”. That is, there is no reason
to believe that states made harder efforts to enrol earlier because of evidence that
families living there where particularly prone to excessive health expenditures. Neither
do we have evidence that excessive health expenditures at the aggregate level have been
13
correlated with higher levels of program diffusion, penetration or coverage. The rates of
incorporation and program coverage at the state and locality levels were driven
primarily by political considerations (party in power); administrative issues (rate at
which clinics and hospitals where accredited to belong to the SP program) and budget
availability.
In addition to estimating the impact of SP on CHE, we also used the same econometric
framework to estimate the effect of SP on out-of-pocket expenditures. We defined out-
of-pocket expenditures as any positive expenditure related to outpatient care, inpatient
care, and medicines. Thus, we created three dichotomous variables equal to the unity if
there was positive spending, and equal to zero otherwise.
To control for important predictors and enrolment and CHE, in the main results for
ENSANUT we controlled for covariates regarding to indigenous language and
indigenous self-identification, as well as the presence of a chronic illness by someone in
the household. Unfortunately those variables were available neither in the ENIGH nor
in the SP Impact Evaluation Survey. Thus, sensitivity analyses exercises tested all the
models using the same set of covariates for the three surveys.
For all model specifications, we compared the results from “naïve” estimates where the
choice of health insurance use was assumed to be exogenous, to the results we obtained
using instrumental variables. Analyses were conducted using STATA™ (StataCorp
2005), including the probit and biprobit procedures.
14
4. RESULTS
Table 1 shows the description of the dependent and explanatory variables for the three
datasets. The main dependent variable was catastrophic health expenditures which were
more comparable in the ENIGH and ENSANUT surveys, than in the SP Impact Survey,
which showed higher CHE. Similarly, out-of-pocket expenditures were also more
prevalent in the SP Impact Survey dataset.
The characteristics of the household-head we analysed included: age, female-headed,
formal education, indigenous self-identity, speak indigenous language. For these
variables we did not find important differences between SP insured vs. uninsured
households, particularly with the ENSANUT and the SP Impact Survey; differences
between the two groups were more noticeable for the ENIGH survey. For both
uninsured and insured groups the mean of the age of the household-head in ENSANUT,
ENIGH and SP impact survey fluctuated between 44 to 50 years. However, the
percentage of household that were female-headed was considerably higher among the
uninsured in the ENIGH with approximately 29% with respect to 21-22% found in the
ENSANUT and SP Impact Survey. In the three surveys the percentage of female-
headed households among the insured was between 19 and 22%. The number of years
of education for the household head was around 5 to 6 years, although in the ENIGH
this variable was considerable lower among the sample of insured households:
approximately only 3.7 years of schooling.
We also included characteristics of the household such as: the household asset index as
a proxy of family income, household size, and benefits from other social programmes,
particularly the Oportunidades programme. At this level, we considered those variables
15
that denoted the composition of the family: children who were one year old or younger,
and children who were 7 years old or younger, as well as adults 65 years-old or older.
For the specific case of ENSANUT we included additional variables that informed us
about the presence of some chronic health conditions among at least one of the members
of the family (diabetes, hypertension and gastritis). The mean for the household asset
index was generally lower for the SP insured population, indicating lower levels of
family wealth. The mean household size was around 3 to 4 members; although this
indicator was slightly higher among SP insured households, particularly in the SP
Impact Survey dataset (with almost 5 members). Differences in the composition of the
household were notable in the percentage with children 7 years-old or younger. While in
the ENIGH this percentage was around 37% in the insured sample, it was considerable
higher (about 53%) in the insured sample in the SP Impact Survey. The percentage of
families with adults 65 years-old or older varied in the three surveys between 15 to 35%
in both insured and uninsured sub-samples.
Comparing insured and uninsured, we did not find statistically significant differences
between households reporting at least one member of with a chronic condition in the
ENSANUT survey. However, we found differences in the percentage of families who
reported to be beneficiaries of the Oportunidades programme among the different
surveys. Specifically, we found a considerable lower percentage of families from the
ENSANUT survey who reported to be benefited from this programme than the rest of
the surveys. Generally, though, across the surveys, SP insured households seemed to be
consistently more enrolled in Oportunidades.
16
At locality level we incorporated variables that described the rural or urban condition of
the municipalities and the deprivation index (CONAPO 2005). While there was 56 to
53% of SP insured households, and 30 to 34% of the uninsured living in rural localities
reported in the ENIGH and ENSANUT surveys, the SP Impact Survey showed 96% of
the insured, and about 89% of uninsured living in rural areas. Most of the households
from the SP Impact Survey were poor, and lived in rural areas with a high deprivation
index. Insured and uninsured households were much poorer in the SP Impact Survey
than in the other two surveys.
Table 2 reports the effect of SP on CHE results for the ENIGH survey. The first two
columns represent the coefficients and marginal effects for the naïve probit model.
Note that the enrolment into Seguro Popular was not a statistically significant
determinant of catastrophic health expenditures. Having an infant less one year of age
or younger increased the probability of CHE by five percentage points; similarly, the
presence of an older adult (65 years of age or older) also increased that probability by
2.2 percentage points.
The last three columns in Table 2 present the bivariate probit model which corrects for
endogeneity in the selection into SP using instrumental variables. First, note that in the
SP equation, the instrumental variables were significant and of the expected sign. Since
there are no formal tests for instrumental variables in the non-linear context, we
conducted informal checks with linear specifications. In the linear models (with all
three data sources), the IVs were highly relevant. The F test statistics of excluded
instruments were very high; all much higher than the “rule of thumb” of 10 to detect
weak instruments (Bound, Jaeger et al. 1995). (Additional details for the linear models
and formal tests are presented elsewhere: Salud Pública de México, forthcoming).
17
Even though the IVs seemed to be working well (longer time of program exposure at
the state level, and higher coverage at the locality level increased the household
probability of having SP insurance), after we addressed the selection issue, we found no
effect of SP on CHE using the ENIGH sample: the effect was not statistically different
from zero.
Table 3 presents the results from the National Health and Nutrition Survey (ENSANUT
2006). As before, we contrasted naïve versus selection-correction non-linear models.
In the naïve probit model, where we estimated the CHE equation independently, we can
see that SP enrolees had a 2 percentage-point lower probability of incurring CHE. On
the other hand, having small children or older adults in the household made CHE more
likely. Similarly, the presence of someone with chronic health conditions (particularly,
diabetes and hypertension) also increased the likelihood of CHE.
In the bivariate probit model, once we addressed selection bias, the effect of SP on
CHE, was even more protective. Households insured with SP had a probability of CHE
that was 3.6 percentage points lower than uninsured households.
The instruments in the ENSANUT data were also significant and worked well. The
seemingly unusual negative sign of “Incorporation by 2003” can be explained as the
effect with respect to the following year. Furthermore, the aggregated effect (adding the
yearly effects) was positive as expected. Households in states that incorporated earlier
to the SP network had a higher probability of enrolling into SP.
18
Note also in the SP equation of Table 3 that that the estimates for the coefficient of
correlation () were positive and significant, meaning that unobservable factors
associated with the outcome (excessive health expenditures) were also associated with
the treatment variable (SP enrolment). That is, household with SP insurance had
unobserved characteristics that made them more likely to incur into CHE.
Table 4 presents the naïve and selection correction models using the SP Impact
Evaluation Survey. Note that the naïve estimate of the protective effect of SP on CHE
was of about 1.8 percentage points, while the effect grew to a 5.3 percentage-point
difference once we corrected for endogeneity.
Table 4 also shows that both instruments were statistically significant, and of the
hypothesized sign. As the SP coverage increased at the locality level, the probability
households to participate in SP also increased. The year of incorporation dummy also
worked as expected. If the state incorporated into SP by 2001, the household
probability of enrolment was larger than if the state incorporated by 2002 (the reference
year in this sample, given that all seven states included in the SP Evaluation Survey
incorporated to SP by 2002). The coefficient of correlation was also positive and
significant as hypothesized.
Table 5 shows the results for the effect of SP on out-of-pocket (OOP) expenditures,
including outpatient care, inpatient care, and medicines. Note that the effect of SP on
outpatient care expenditures was protective for all the samples, but was much stronger
for the SP Impact Survey population. On the other hand, we found a protective effect
against inpatient care expenditures only in the SP Impact Survey population; the effect
19
was not different from zero in the other two datasets. Finally, for out-of-pocket
expenditures related to medicines, we found again that SP reduced the probability of
spending out-of-pocket for medicines for all samples, but the effect was stronger in the
SP Impact Survey.
5. DISCUSSION
The overall larger protective effect of Seguro Popular on catastrophic health
expenditures (CHE) and out-of-pocket expenditures in the SP Impact Evaluation Survey
can be explained as that survey was targeted to a population with lower socio-economic
status. As seen in Table 1, the SP Impact Survey population was poorer, more rural,
and in more marginalized communities. On the other hand, the ENSANUT and ENIGH
surveys are nationally representative samples of the entire Mexican population
(including middle- and high-income households). It is expected then that the effect of
SP on the general population be somewhat diminished.
The ENIGH survey has the advantage of being more accurate in collecting information
about the total household’s expenditure in comparison to the other two surveys.
Although ENSANUT and the SP Impact Evaluation Survey had similar contents,
mainly related to health and use of health services; the first one is representative at
nationally level, whilst the second one was gathered in a few states in Mexico where the
SP programme had a low rate of SP penetration at the time of the development of the
survey. Note that the differences between ENSANUT and ENIGH were not due to the
additional control variables in ENSANUT. In Appendix Tables A1 and A2 we show
that the protective effect of SP on CHE is still present when we do not control for
20
indigenous language and self-identity and the chronic health condition variables in
ENSANUT.
By using the same non-experimental (IV) approach and the same covariates with all
three datasets, we can ascribe the differences in results to the differences in data
collection methods only. Nevertheless, it is still puzzling that no effect is observed
using the ENIGH, but that a significant protective effect of SP against CHE is present in
both ENSANUT and the SP Impact Survey.
On the other hand, note that our results of SP program participation on CHE are similar
to those found by King and collaborators (King and et al 2006; King, Gakidou et al.
2007), when analyzing experimental data with the SP Impact Evaluation Survey. They
found that SP reduces the probability of incurring catastrophic health expenditures by
1.5% (intention to treat analysis) and by 3% using the complier causal average effect
(CACE). These differences with our results are explained from the treatment effect
methodology used, although in both cases the effects were significant.
21
6. CONCLUSION AND LIMITATIONS
The results in this paper show that the universal insurance system for the poor in
Mexico, Seguro Popular, has a protective effect on excessive health expenditures, as
well as out-of-pocket health-related expenditures, particularly for the poorest segments
of the population.
Given these results, the SP program should continue to concentrate in enrolling the
poorest households, in the most marginalized localities, because it is in those
populations where we observe a higher prevalence of excessive health expenditures, but
also where the SP program seems to be more effective for financial protection.
The fact that we have defined our analytical sample for insured households as only
those where all members of households are enrolled in SP, is likely to be under-
estimating the number of families enrolled in SP, and the potential effect of the
programme. In that sense, given the strict criteria to define the analytical sample, we
view the results provided as conservative estimates.
One of the limitations of the definition of catastrophic health expenditures is the fact
that it does not consider all those households that postpone their health care for the lack
of financial resources. We do not address the issue of selection into CHE. Health
expenditure is, by definition, conditional on utilization. Thus, there is another possible
econometric specification to take into account of the endogeneity generated by health
seeking behavior. Such correction requires specific data on non-users (which was not
available to us); just a few papers attempt to correct such inherent endogeneity (Pradhan
and Prescott 2002; Hatt 2006).
22
The present analysis does not include other alternative indicators that can also describe
the effect of the incidence of health expenditures on the household’s financial status
such as the impoverishing expenditures; which are the expenditures do not provoke
family’s bankruptcy but do move the household’s economic status below the poverty
line.
Lastly, at the household level, the cross-sectional surveys do not provide information
about the length of treatment (i.e., how long the households have been enrolled in the
SP programme), which could have an important effect on excessive health expenditures.
ACKNOWLEDGEMENTS
We thank Martha Maria Tellez-Rojo, Gustavo Nigenda, and Miguel Angel González-
Block for inviting us to participate in the 2007 Seguro Popular Program Evaluation
Team, sponsored by the Mexican Ministry of Health. The results presented in this
paper constitute additional work conducted by the authors. The views do not represent
the official position of any of the institutions mentioned. The authors are solely
responsible for the contents.
23
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26
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27
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!&!!"$!% -# -# # -# -#
B#CDD B#CDD B#CDD B#CD B#CD

7$!% # # # # #
B#CDD B#CDD B#CDD B#CDD B#CDD
89! # # -# # #
B#C B#C B#CDD B#C B#C
 
:.9* #
B#CDD
'!4.$!% #
B#C
'!4.$!% #
B#CDD
'!4.$!% #
B#C
'!4.$!% -#
B#CD
 #
B#C
" -# -# -#
B#CDD B#CDD B#CDD
&4"9"  
=";,*//"",!,/99
&
#
$!%,*"/!"*/!,,.94/,
4""!!"40"
E"*/F GD"*/FGDD"*/F
AA
' !"#'(()*+++# ,
=94( ! H94(!
28
A
//"
(*//"
//"
//"
(*//"
!*$!% -# -# -# -#
B#CDD B#CDD B#CDD B#CDD

)* # # -# # #
B#CDD B#CDD B#CDD B#CDD B#CDD
+,-!!$!% -# -# -# -# -#
B#C B#C B#CD B#C B#C
+,!$,4/."% -# -# -# -# -#
B#C B#C B#CDD B#CE B#CE
'!*""/-!.$!% # # -# # #
B#C B#C B#CDD B#C B#C
0!*"**$!% -# -# -# -# -#
B#CDD B#CDD B#C B#CDD B#CDD

)""'! # # -# # #
B#C B#C B#CD B#C B#C
!1$!% # # -# # #
B#CDD B#CDD B#CDD B#CDD B#CDD
!1$!% # # # # #
B#C B#C B#CDD B#C B#C
)!"2$!% # # -# # #
B#CDD B#CD B#C B#CDD B#CD
,3!4"$!% # # # # #
B#CD B#CD B#CD B#CD B#CD
,3."$!% # # # # #
B#CE B#CE B#CDD B#CE B#CE
,3*""$!% # # # # #
B#CE B#C B#CE B#CE B#C
+,."5 -# -# -# -# -#
B#CDD B#CDD B#CDD B#CDD B#CDD
!& !!"$!% -# -# # -# -#
B#C B#C B#CDD B#C B#C

7$!% # # -# # #
B#CD B#CD B#CDD B#CDD B#CDD
89! # # -# # #
B#CDD B#CDD B#CDD B#CDD B#CDD

:.9* #
B#CDD
'!4.$!% #
B#CDD
'!4.$!% #
B#C
'!4.$!% -#
B#CDD
'!4.$!% #
B#C
///$% #
B#CDD
" -# -# -#
B#CDD B#CDD B#CDD
&4"9"  
=";,*//"",!,/99
&
#
$!%,*"/!"*/!,,.94/,
4""!!"40"
E"*/F GD"*/FGDD"*/F
-$ %'(()*+++# ,
=94(! H94(!
A A
29
A
//"
(*
//"
//"
//"
(*
//"
!*$!% -# -# -# -#
B#CDD B#CDD B#CDD B#CDD

)* # # -# # #
B#CDD B#CDD B#CE B#CDD B#CDD
+,-!!$!% # # # # #
B#C B#C B#CE B#C B#C
+,!$,4/."% -# -# -# -# -#
B#CDD B#CDD B#C B#CDD B#CDD

)""'! -# -# -# -# -#
B#CDD B#CDD B#CDD B#CDD B#CDD
!1$!% # # # # #
B#CDD B#CDD B#C B#CDD B#CDD
!1$!% -# # # # #
B#C B#C B#CDD B#C B#C
)!"2$!% # # -# # #
B#CDD B#CDD B#C B#CDD B#CDD
+,."5 -# -# # -# -#
B#CDD B#CDD B#CDD B#CDD B#CDD
!&!!"$!% -# -# # # #
B#CD B#CD B#CDD B#C B#C

7$!% # # -# # #
B#CDD B#CDD B#CDD B#CDD B#CDD
89! # # # # #
B#CDD B#CDD B#CDD B#CDD B#CDD
 
:.9* #
B#CDD
'!4.$!% #
B#CD
///$% #
B#CDD
" -# -# -#
B#CDD B#CDD B#CDD
&4"9"  
=";,*//"",!,/99
&
#
$!%,*"/!"*/!,,.94/,
4""!!"40"
E"*/FGD"*/FGDD"*/F
.!*+++#,
=94( !
A
H94(!
A
30
///&&
!"
//"
(*
//"
//"
(*
//"
//"
(*
//"
& -# -# -# -# -# -#
B#CDD B#CDD B#CDD B#CDD B#CDD B#CDD
' -# -# # # -# -#
B#C B#C B#C B#C B#CDD B#CDD
(!" -# -# -# -# -# -#
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... Estos últimos estudios están basados en un experimento específicamente diseñado para realizar la evaluación del SP. En lo que se refiere al gasto catastrófico en salud, algunos autores encuentran evidencia de que el SP tiene el efecto de proteger en contra de pagos catastróficos (Gakidou et al., 2006), sobre todo en el caso de las familias más pobres (Galárraga et al., 2008). Asimismo, otros autores observan que el gasto en salud del hogar y el gasto catastrófico en salud es menor para los hogares afiliados al SP en comparación con los no asegurados (Scott, 2006;Barros, 2009;y Hernández-Torres, 2008). ...
... Por el contrario, otros estudios indican que el SP no ha tenido ningún impacto en el gasto catastrófico en salud. Por ejemplo, Galárraga et al. (2008), usando la ENIGH, encuentran que no hay impacto del SP en el gasto catastrófico en salud, pero establecen que sí existe una reducción en el gasto total en salud del hogar en medicinas y en servicios de salud. Por otro lado, al utilizar la ENSANUT y la Encuesta de Impacto del Seguro Popular, dichos autores observan que estar afiliado al SP reduce la probabilidad de incurrir en gasto catastrófico, en gasto en medicinas y de servicios de salud. ...
Article
This article examines the impact of Seguro Popular (SP) in health services utilization, in the labor market, and in household health expenditures. Benefiting from longitudinal data from the Mexican Family Life Survey, we use propensity score matching techniques to analyze the data by gender and population origin. In general, the SP has not impacted the number of hospitalizations and out-patient consultations, with the exception of urban women. The analysis by institution shows that, in urban populations, the SP has increased external consultations in the health care facilities provided by the Health Ministry. The SP shows a negative impact in the Mexican Institute of Social Security coverage, and in the formal employment of urban women and rural men. At the household level, we do not find any effect on household health expenditures.
... Estos últimos estudios están basados en un experimento específicamente diseñado para realizar la evaluación del SP. En lo que se refiere al gasto catastrófico en salud, algunos autores encuentran evidencia de que el SP tiene el efecto de proteger en los casos en los que se incurre en pagos catastróficos (Gakidou et al., 2006), sobre todo en el caso de las familias más pobres (Galárraga et al., 2008). Asimismo, otros autores observan que el gasto en salud del hogar y el gasto catastrófico en salud es menor para los hogares afiliados al SP en comparación con los no asegurados (Scott, 2006;Barros, 2009;y Hernández-Torres, 2008). ...
... Por el contrario, otros estudios indican que el SP no ha tenido ningún impacto en el gasto catastrófico en salud. Por ejemplo, Galárraga et al. (2008), usando la ENIGH, encuentran que no hay impacto del SP en el gasto catastrófico en salud, pero establecen que sí existe una reducción en el gasto total en salud del hogar en medicinas y en servicios de salud. Por otro lado, al utilizar la ENSANUT y la Encuesta de Impacto del Seguro Popular, dichos autores observan que estar afiliado al SP reduce la probabilidad de incurrir en gasto catastrófico, en gasto en medicinas y de servicios de salud. ...
Article
Full-text available
This article examines the impact of Seguro Popular (SP) in health services utilization, in the labor market, and in household health expenditures. Benefiting from longitudinal data from the Mexican Family Life Survey, we use propensity score matching techniques to analyze the data by gender and population origin. In general, the SP has not impacted the number of hospitalizations and out-patient consultations, with the exception of urban women. The analysis by institution shows that, in urban populations, the SP has increased external consultations in the health care facilities provided by the Health Ministry. The SP shows a negative impact in the Mexican Institute of Social Security coverage, and in the formal employment of urban women and rural men. At the household level, we do not find any effect on household health expenditures.
... Galárraga et al also concluded that households with members suffering from diabetes, hypertension, and gastritis were more likely to be exposed to CHE even with an insurance coverage. 30 It is suggested that adding a patient or a disabled member to a household increased the likelihood of confronting CHE in health services by 3%. 40 The results of these studies are also in agreement with findings of the current research. ...
Article
Full-text available
Introduction: One of the main objectives of health systems is providing financial protection against out-of-pocket (OOP) health expenditures. According to the 2011 report by the World Health Organization in the Eastern Mediterranean Regional Office (EMRO), a huge portion of health service in Iran is paid OOP, which is around 58% of the total health system expenditure. Furthermore, all over the world, around 25 million households (100 million people) are trapped in poverty as a result of paying health service costs. Therefore, this research was aimed at investigating the OOP and exposure of households with catastrophic health expenditures (CHE) following the implementation of a health transformation plan in Tabriz, Iran. Methods: A descriptive-analytic study was conducted on a cross-sectional basis. The sample included 400 households, who were interviewed using the World Health Survey questionnaire, and then OOP payment and exposure of households to CHE were estimated, and the effective factors on OOP payment and the determinants of CHE were analyzed using a regression model. Results: After implementing the health transformation plan, the average share of households' OOP payments, toward their ability to pay was 13.2%. In addition, 11.25% of the households were exposed to CHE in Tabriz. The key determinants of OOP were income, dental services, pharmaceuticals, radiology, and physiotherapy. The factors affecting CHE were income, insurance status, marital status, dental services, pharmacy, physiotherapy, and radiological services. Conclusion: Based on the results of the current study and compared to similar research conducted prior to this plan, it is obvious that the transformation plan was able to achieve its goal in "reducing OOP payments". However, health services such as dental, pharmacy, physiotherapy, and radiology would increase the likelihood of facing OOP payments. These variables should be considered by health policy-makers in order to review and revise the content of recent reform to provide financial protection against OOP for people.
... In terms of measuring fairness in the financial burden of health costs on individuals, a theoretical framework provided by WHO is based on the approach that a health system is fairly financed when all households dedicate the same share of their capacity or ability to pay (effective nonsubsistence income) to receiving the required healthcare services. This index was formally introduced by WHO in its annual report of 2000 (6,7) and was used and developed subsequently by many researchers (8)(9)(10)(11)(12)(13)(14)(15)(16). According to this approach, WHO defined the index of the FFC, formulated as follows: ...
Article
Full-text available
Background Two years after the implementation of the Health Sector Evolution Plan (HSEP), this study evaluated the effects of the plan on health equity indices. Methods The main indices assessed by the study were the Out-of-Pocket (OOP) health expenditures, the Fairness in Financial Contribution (FFC) to the health system index, the index of households’ Catastrophic Health Expenditure (CHE) and the headcount ratio of Impoverishing Health Expenditure (IHE). Results The per capita share of costs for total health services has been decreased. The lowered costs have been more felt in rural areas, generally due to sharp decrease in inpatient costs. Per capita pay for outpatient services is almost constant or has slightly increased. The reform plan has managed to improve households’ Catastrophic Health Expenditure (CHE) index from an average of 2.9% before the implementation of the plan to 2.3% after the plan. The Fairness in Financial Contribution (FFC) to the health system index has worsened from 0.79 to 0.76, and the headcount ratio of Impoverishing Health Expenditure (IHE) index deteriorated after the implementation of plan from 0.34 to 0.50. Conclusion Considerable improvement, in decreasing the burden of catastrophic hospital costs in low income strata which is about 26% relative to the time before the implementation of the plan can be regarded as the main achievement of the plan, whereas the worsening in the headcount ratio of IHE and FFC are the equity bottlenecks of the plan.
... Moreover, Wagstaff and Lindelow (2008) show that in urban China health insurance has in fact increased OOP and catastrophic payments, which they attribute to a combination of increased utilization and behavioural responses by health care providers. Studies in Latin America find evidence of decreased OOP health payments and catastrophic health care spending in Mexico due to the Seguro Popular health insurance for the poor (Galárraga, Sosa-Rubí, Salinas, & Sesma, 2008), and increased health care utilization in Colombia due to subsidized health insurance for the poor (Giedion, 2007;Trujillo, Portillo, & Vernon, 2005) and mandatory contributory based health insurance for the non-poor (Giedion, Alfonso, & Díaz, 2007). For Indonesia, Hidayat, Thabrany, Dong, and Sauerborn (2004) find a positive effect of mandatory formal sector health insurance on utilization of outpatient care in the 1990s. ...
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A first step towards meeting Indonesia's ambition for universal health insurance was made in 2005 with the introduction of the Askeskin programme, a subsidized social health insurance targeted to the informal sector and the poor. This paper investigates targeting and impact of the Askeskin programme using panel data for 8582 households observed in 2005 and 2006, and applying difference-in-differences estimation in combination with propensity score matching. We find that the programme is indeed targeted to the poor and those most vulnerable to catastrophic out-of-pocket health payments. Social health insurance improves access to health care in that it increases utilization of outpatient among the poor, while out-of-pocket spending seems to have increased for Askeskin insured in urban areas.
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Out-of-pocket payments for healthcare not only limit access to healthcare but also negatively affect household welfare. It has been argued that assessment of health system performance with regards to protecting households from financial risk due to out-of-pocket payments should not only address equity concerns that arise with regards to quantifying financial risk but should also identify households that are most vulnerable to that risk. This study assesses the extent and intensity of financial risk due to out-of-pocket payments in Uganda and also identifies households that are most vulnerable to that risk.Results indicate that households in Uganda generally lack financial protection. For instance, 22.8% of all households spend over 10% of their total household consumption expenditure paying out-of-pocket for health care. The mean excess payment above the 10% threshold for those that exceed it is equal to 11% of that threshold. Furthermore, 4.3% Ugandans are impoverished due to out-of-pocket health payments representing a 17.6% rise in poverty headcount (from 24.5% to 28.7%). Households with a member aged above 65 years or a member aged below five years were found to have a higher likelihood of incurring both catastrophic payments and impoverishment. While the utilisation of both public and private health facilities were both associated with a high likelihood of financial risk, this risk was higher among households that used private facilities.There is a need for concerted efforts aimed at reducing the level of out-of-pocket payments for health care in Uganda. This is achievable by adopting mandatory prepayment mechanism to finance health care. Initiatives for reducing out-of-pocket payments should target the most vulnerable households as identified in the study.
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This article proposes a critical but non-systematic review of recent health care system reforms in developing countries. The literature reports mixed results as to whether reforms improve the financial protection of the poor or not. We discuss the reasons for these differences by comparing three representative countries: Mexico, Vietnam, and China. First, the design of the health care system reform, as well as the summary of its evaluation, is briefly described for each country. Then, the discussion is developed along two lines: policy design and evaluation methodology. The review suggests that i) background differences, such as social development, poverty level, and population health should be considered when taking other countries as a model; ii) although demand-side reforms can be improved, more attention should be paid to supply-side reforms; and iii) the findings of empirical evaluation might be biased due to the evaluation design, the choice of outcome, data quality, and evaluation methodology, which should be borne in mind when designing health care system reforms.
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Absence of financial protection in health is a recently diagnosed "disease" of health systems. The most obvious symptom is that families face economic ruin and poverty as a consequence of financing their health care. Mexico was one of the first countries to diagnose the problem, attribute it to lack of financial protection, and propose systemic therapy through health reform. In this article we assess how Mexico turned evidence on catastrophic and impoverishing health spending into a catalyst for institutional renovation through the reform that created Seguro Popular de Salud (Popular Health Insurance). We present 15-year trends on the evolution of catastrophic and impoverishing health spending, including evidence on how the situation is improving. The results of the Mexican experience suggest an important role for the organisation and financing of the health system in reducing impoverishment and protecting households during periods of individual and collective financial crisis.
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The method of instrumental variables was first used in the 1920s to estimate supply and demand elasticities, and later used to correct for measurement error in single-equation models. Recently, instrumental variables have been widely used to reduce bias from omitted variables in estimates of causal relationships such as the effect of schooling on earnings. Intuitively, instrumental variables methods use only a portion of the variability in key variables to estimate the relationships of interest; if the instruments are valid, that portion is unrelated to the omitted variables. We discuss the mechanics of instrumental variables, and the qualities that make for a good instrument, devoting particular attention to instruments that are derived from 'natural experiments.' A key feature of the natural experiments approach is the transparency and refutability of identifying assumptions. We also discuss the use of instrumental variables in randomized experiments.
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We outline a framework for causal inference in settings where assignment to a binary treatment is ignorable, but compliance with the assignment is not perfect so that the receipt of treatment is nonignorable. To address the problems associated with comparing subjects by the ignorable assignment - an "intention-to-treat analysis" - we make use of instrumental variables, which have long been used by economists in the context of regression models with constant treatment effects. We show that the instrumental variables (IV) estimand can be embedded within the Rubin Causal Model (RCM) and that under some simple and easily interpretable assumptions, the IV estimand is the average causal effect for a subgroup of units, the compliers. Without these assumptions, the IV estimand is simply the ratio of intention-to-treat causal estimands with no interpretation as an average causal effect. The advantages of embedding the IV approach in the RCM are that it clarifies the nature of critical assumptions needed for a causal interpretation, and moreover allows us to consider sensitivity of the results to deviations from key assumptions in a straightforward manner. We apply our analysis to estimate the effect of veteran status in the Vietnam era on mortality, using the lottery number that assigned priority for the draft as an instrument, and we use our results to investigate the sensitivity of the conclusions to critical assumptions.
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To document trends in financial protection in the health care system in Mexico between 1992 and 2004, applying a series of indicators that measure catastrophic and impoverishing health spending and the Index of Fairness in Financial Contributions. MATERIALS Y METHODS: This study uses the biannual time series of the Survey of Household Income and Expenditures (ENIGH) spanning the period 1992 to 2004. The methodologies seek to measure the level and distribution of the burden of health care finance on households, and the financial protection offered to them by the health care system. Four indicators are presented: 1) the Index of Fairness in Financial Contributions, 2) the proportion of households with catastrophic health expenditure, 3) the proportion of households with impoverishment due to health spending and 4) the sum of the proportion of households with catastrophic or impoverishing health spending, which is referred to as excessive health spending. The analysis presented in this document is descriptive, leaving for later studies a deeper analysis of causal aspects. The number of families that suffer impoverishment due to health spending increased from 5.2% in 1992, reached a high of 9.9% in 1996, and then gradually declined to 1.8% by 2004. The proportion of households with catastrophic expenses began at 2.8% in 1992, increased to 4.2% in 1998 and then fell to a level of 2.6% in 2004. The improvements from 2000 on are concentrated among the uninsured population, families affiliated to Popular Health Insurance, and households in the poorest two quintiles of the income distribution. The patterns over time in excessive health spending reflect a worsening during periods of economic crisis, post-crisis recovery, and a sustained improvement beginning in the year 2000. The data suggest that part of the reduction in the number of households with excessive health spending is due to the extension of financial protection for Mexican families through the Popular Health Insurance, while another part is associated with a decline in poverty. In addition,this paper documents an important relationship between economic trends and catastrophic and impoverishing health spending, suggesting the importance of financially protecting families through health insurance. Financial protection assists in guaranteeing that when economic crisis--of a country or of a family--coincides with illness, health care payments do not become the cause of a long or permanent period of impoverishment for households.
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Since 2001, Mexico has been designing, legislating, and implementing a major health-system reform. A key component was the creation of Seguro Popular, which is intended to expand insurance coverage over seven years to uninsured people, nearly half the total population at the start of 2001. The reform included five actions: legislation of entitlement per family affiliated which, with full implementation, will increase public spending on health by 0.8-1.0% of gross domestic product; creation of explicit benefits packages; allocation of monies to decentralised state ministries of health in proportion to number of families affiliated; division of federal resources flowing to states into separate funds for personal and non-personal health services; and creation of a fund to protect families against catastrophic health expenditures. Using the WHO health-systems framework, a wide range of datasets to assess the effect of this reform on different dimensions of the health system was used. Key findings include: affiliation is preferentially reaching the poor and the marginalised communities; federal non-social security expenditure in real per-head terms increased by 38% from 2000 to 2005; equity of public-health expenditure across states improved; Seguro Popular affiliates used more inpatient and outpatient services than uninsured people; effective coverage of 11 interventions has improved between 2000 and 2005-06; inequalities in effective coverage across states and wealth deciles has decreased over this period; catastrophic expenditures for Seguro Popular affiliates are lower than for uninsured people even though use of services has increased. We present some lessons for Mexico based on this interim evaluation and explore implications for other countries considering health reforms.