Diagnosis and Treatment of Pediatric Psoriasis: Current and Future

ArticleinAmerican Journal of Clinical Dermatology 14(3) · May 2013with13 Reads
Impact Factor: 2.73 · DOI: 10.1007/s40257-013-0026-8 · Source: PubMed


    Psoriasis is a common yet complex inflammatory dermatosis that may be seen in infants, children, and adolescents. The clinical presentation and course may be quite variable, and while patients with mild disease are often easily managed, those with recalcitrant or more severe disease often present a therapeutic dilemma given the number of therapies available and the relative lack of data on the efficacy and safety of use of these therapies in children. This review presents the reader with an overview of the current understanding of the pathophysiology, diagnosis, and treatment of pediatric psoriasis, with an emphasis on the available data in the literature that pertains to the use in children of currently available topical and systemic therapies, including topical corticosteroids, vitamin D analogs, phototherapy, systemic immunosuppressive medications, and biologic agents.