Meteorological parameters and seasonal variations in pulmonary thromboembolism
Department of Chest, School of Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey. The American journal of emergency medicine
(Impact Factor: 1.27).
11/2008; 26(9):1035-41. DOI: 10.1016/j.ajem.2007.12.010
In recent years, circannual variations in incidence and mortality for venous thromboembolic disease have been demonstrated, with a peak in winter. However, several investigators have observed no seasonal variation in these diseases. The aim of our study was to investigate whether a seasonal variation, in terms of atmospheric pressure, humidity, and temperature, exists for pulmonary thromboembolism.
We retrospectively included 206 patients with a diagnosis of pulmonary embolism (PE) between 1 June 2001 and 31 May 2006.
The highest number of cases in the 5 years concerned occurred in May (29 cases). Although PE occurred most commonly in the spring (72 cases) and autumn (51 cases), the difference was statistically significant (P = .003). There were no case correlations with months and pressure, temperature, or humidity. However, there was a statistically significant positive correlation between case incidence and atmospheric pressure (r = 0.53, P < .0005) and humidity (r = 0.57, P < .0005). In terms of risk factors, seasonal distribution was not statistically significant as regards cases of embolism occurring for surgical or nonsurgical reasons (r = 0.588).
In terms of the relationship between seasons and embolism cases, despite the determination of an insignificant positive correlation, a statistically significant positive correlation was determined between air pressure and humidity and case incidence. There is now a need for further wide-ranging prospective studies including various hematological parameters to clarify the correlation between PE and air pressure.
Available from: Samad SHAMS Vahdati
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ABSTRACT: Pulmonary thromboembolism (PTE) is an important health problem. It is disease with a wide clinical spectrum, from asymptomatic small PTE to life threatening major PTE. In this manuscript, we evaluated studies performed in Turkey to determine national status about PTE. We were examined that published in national or international journals, or abstracts presented in congresses from 1991 to nowadays, excluding reviews or case studies. Among the 75 studies, performed in Turkey, related this topic, the most common complaints in PTE were dyspnea and chest pain. Surgery and immobilization were the most frequent risk factors causing PTE, however cancers were rarely reported as a risk factor. The most common findings of chest radiography were parenchymal infiltration and pleural effusion. While the diagnosis of PTE were mostly based on clinical findings and lung scan findings in the earlier studies, spiral thorax computed tomography became an important tool of diagnosis recently, specially after the years of 2000. Interesting, mortality rates in massive PTE were found lower than the literature. In conclusion, the number of patients with PTE is increased due to developments in the diagnosis of PTE. Our national findings commonly comply with the international literature. However, we think the documentation of current national status in PTE requires more comprehensive studies.
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ABSTRACT: Seasonal variations in the incidence of cardiovascular disease, mainly characterized by a winter peak, have been consistently reported. Some evidence now also exists on potential seasonal variations in the incidence of venous thromboembolism (VTE). Of interest, seasonal variability in the incidence of deep vein thrombosis and fatal and nonfatal pulmonary embolism appears to differ; however, the results of available studies are not unequivocal. This review will briefly summarize current evidence in this area.
Recent studies indicate a seasonal variability in the incidence of VTE, with a pattern that is independent of sex, age, type of event, or underlying risk factors. Usually, these studies found a higher VTE incidence during the winter months and a lower incidence in the summer months. The exact mechanism of this variability is not completely understood, but it may be at least in part explained by changes in coagulation factor levels.
Confirmation of these findings and a better understanding of underlying mechanisms could help physicians to identify patients or periods with increased risk of VTE in order to further improve current prophylactic strategies.
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