Endometriosis, dysmenorrhoea and diet

ArticleinEuropean journal of obstetrics, gynecology, and reproductive biology 169(2) · May 2013with38 Reads
DOI: 10.1016/j.ejogrb.2013.03.028 · Source: PubMed
Objective: To review the literature on the effects of diet on endometriosis and dysmenorrhoea. Study design: A systematic search for trials investigating a relationship between diet and endometriosis/dysmenorrhoea was undertaken, and 23 studies were included in this review. Results: Data on the relationship between diet and endometriosis were limited to 12 trials, three of which were animal studies, resulting in a total of 74,708 women. One large study (n=70,709) found a relatively strong association between endometriosis and trans-fatty acid consumption, and a lower risk of endometriosis with increased consumption of long-chain omega-3 fatty acids. The latter finding was also supported by smaller studies. No further dietary recommendations for reducing the risk of endometriosis were possible, and results for intake of vegetable, fibre and fruit were equivocal. The relationship between diet and dysmenorrhoea was investigated in 11 trials with different designs, including a total of 1433 women. Intake of fish oil seemed to reduce dysmenorrhoea. Conclusion: The literature on endometriosis and dysmenorrhoea in relation to diet is sparse, yielding equivocal results on specific elements. Overall, however, the literature suggests that specific types of dietary fats are associated with endometriosis and/or dysmenorrhoea, thereby indicating that there may be modifiable risk factors. Further research is recommended on both subjects.
    • "While the mechanisms underlying the adverse effects of skipping a meal are unclear, they may relate to the inadequate intake of certain foods. For example, many studies have reported that low intake of certain polyunsaturated fatty acids (Tokuyama and Nakamoto 2011; Hansen and Knudsen 2013), which have anti-inflammatory effects, may enhance pain. In addition, low intake of dairy products (Abdul-Razzak et al. 2010) and dietary fiber (Nagata et al. 2005) may relieve dysmenorrheal pain. "
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